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IL-7 and IL-15 Levels Reflect the Degree of T Cell Depletion during Lymphopenia and Are Associated with an Expansion of Effector Memory T Cells after Pediatric Hematopoietic Stem Cell Transplantation
Katrine Kielsen, Lisa V. E. Oostenbrink, Erik G. J. von Asmuth, Anja M. Jansen-Hoogendijk, Monique M. van Ostaijen-ten Dam, Marianne Ifversen, +8 more
16citations -
Prospective Open-Label Phase II Trial of Individualized Anti-Thymocyte Globulin for Improved T-Cell Reconstitution after Pediatric Allogeneic Hematopoietic Cell Transplantation: The Parachute-Study2020 Transplantation and Cellular Therapy article Medicine Hematopoietic Stem Cell Transplantation Open access
Rick Admiraal, Stefan Nierkens, Robbert G. M. Bredius, Marc Bierings, Ineke van Vliet, Marta Lopez Yurda, +4 more
10citations -
HA-1H T-Cell Receptor Gene Transfer to Redirect Virus-Specific T Cells for Treatment of Hematological Malignancies After Allogeneic Stem Cell Transplantation: A Phase 1 Clinical Study
Peter van Balen, Inge Jedema, Marleen M. van Loenen, Renate de Boer, H.M. van Egmond, Renate S. Hagedoorn, +9 more
42citations -
A Bispecific γδ T-cell Engager Targeting EGFR Activates a Potent Vγ9Vδ2 T cell–Mediated Immune Response against EGFR-Expressing Tumors2023 Cancer Immunology Research article Medicine Cancer Immunotherapy and Biomarkers Open access cited by 1 patent
Lisa A. King, Elisa C. Toffoli, Myrthe Veth, Victoria Iglesias‐Guimarais, Manon C. Slot, Derk Amsen, +11 more
42citations -
A library of cancer testis specific T cell receptors for T cell receptor gene therapy2022 Molecular Therapy — Oncolytics article Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 2 patents
Marije A. J. de Rooij, Dennis F.G. Remst, Dirk M. van der Steen, Anne K. Wouters, Renate S. Hagedoorn, Michel G.D. Kester, +7 more
19citations -
Public T-Cell Receptors (TCRs) Revisited by Analysis of the Magnitude of Identical and Highly-Similar TCRs in Virus-Specific T-Cell Repertoires of Healthy Individuals2022 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Wesley Huisman, Lois Hageman, Didier A.T. Leboux, Alexandra A. Khmelevskaya, Grigory Aleksandrovich Efimov, Marthe C.J. Roex, +3 more
35citations -
CD3 aptamers promote expansion and persistence of tumor-reactive T cells for adoptive T cell therapy in cancer2024 Molecular Therapy — Nucleic Acids article Medicine CAR-T cell therapy research Open access cited by 3 patents
Ashwathi Puravankara Menon, Helena Villanueva, Daniel Meraviglia-Crivelli, Hisse M. van Santen, Joschka Hellmeier, Angelina Zheleva, +9 more
7citations -
Human CD34+-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8+ T cell and NK cell responses in vitro and in vivo2023 Cellular and Molecular Life Sciences article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Jesper van Eck van der Sluijs, Diede van Ens, Jolanda Brummelman, Daan Heister, Aastha Sareen, Lisa Truijen, +9 more
4citations -
Dendritic cell vaccination and CD40-agonist combination therapy licenses T cell-dependent antitumor immunity in a pancreatic carcinoma murine model2020 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Sai Ping Lau, Nadine van Montfoort, Priscilla Kinderman, Melanie M. Lukkes, Larissa Klaase, Menno van Nimwegen, +15 more
65citations -
DNA-demethylation by DAC induces MAGE expression and MAGE-specific T cell reactivity against tumors but also healthy cell subsets2025 Molecular Therapy Oncology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Marije A. J. de Rooij, Miranda H. Meeuwsen, Anne K. Wouters, Dennis F.G. Remst, Renate S. Hagedoorn, Dirk M. van der Steen, +4 more
0citations -
Generation of effective and specific human TCRs against tumor/testis antigen NY-ESO-1 in mice with humanized T cell recognition system2024 Frontiers in Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Xiaojing Tina Chen, Matthias Leisegang, Ioannis Gavvovidis, Seth M. Pollack, Felix K.M. Lorenz, Ton N. Schumacher, +2 more
6citations -
Priming of Allo-HLA-DP-Specific Reactivity from the Naïve T Cell Compartment Is Not Exclusively Mediated by Professional Antigen-Presenting Cells2020 Transplantation and Cellular Therapy article Medicine Hematopoietic Stem Cell Transplantation Open access
Aicha Laghmouchi, Conny Hoogstraten, J.H. Frederik Falkenburg, Inge Jedema
1citations -
CD4+ T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors2024 Cellular and Molecular Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Xin Lei, Daniël de Groot, Marij J.P. Welters, Tom de Wit, Ellen Schrama, Hans van Eenennaam, +10 more
65citations -
Preferential HLA-B27 Allorecognition Displayed by Multiple Cross-Reactive Antiviral CD8+ T Cell Receptors2020 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Louise C. Rowntree, Heleen van den Heuvel, Jessica D. Sun, Lloyd J. A. D'Orsogna, Thi H. O. Nguyen, Frans H.J. Claas, +4 more
13citations