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Enhancing anti-tumor immunity through liposomal oxaliplatin and localized immunotherapy via STING activation2023 Journal of Controlled Release article Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 2 patents
Zili Gu, Timo Schomann, FERRY A. OSSENDORP, Peter ten Dijke, Luis Javier Cruz
86citations -
STING loss attenuates ISG expression without affecting PARP inhibitor sensitivity in Brca1+/− Jak2V617F MPN2026 Scientific Reports article Immunology and Microbiology interferon and immune responses Open access
Mirjam Hanako Sarholz, María Jimena Rodriguez, Tomasz Skórski, Steffen Koschmieder, Julian Baumeister
0citations -
Sequential STING and CD40 agonism drives massive expansion of tumor-specific T cells in liposomal peptide vaccines2025 Cellular and Molecular Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Dmitrij Ostroumov, Naomi Benne, Fernando Lozano Vigario, Oscar Escalona-Rayo, Ksenia Dodz, Sarah Sauer, +5 more
9citations -
Gram-positive bacteria secrete RNA aptamers to activate human STING for IL-1β release2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Inflammasome and immune disorders Open access
Shivalee N. Duduskar, Mohamed Ghait, Martin Westermann, Huijuan Guo, Anuradha Ramoji, Christoph Sponholz, +11 more
0citations -
Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing2022 The Journal of Experimental Medicine article Medicine Vasculitis and related conditions Open access cited by 2 patents
Nina Kessler, Susanne F. Viehmann, Calvin Krollmann, Karola Mai, Katharina M. Kirschner, Hella Luksch, +21 more
56citations -
Reversibility of Endoplasmic Reticulum Stress Markers During Long-Term Glucose Starvation in Astrocytes2024 Journal of Molecular Neuroscience article Biochemistry, Genetics and Molecular Biology Endoplasmic Reticulum Stress and Disease Open access
Clara Voelz, Lena Schaack, Vanessa Kogel, Cordian Beyer, Jochen Seitz, Stefanie Trinh
1citations -
Rare longevity-associated variants, including a reduced-function mutation in cGAS, identified in multigenerational long-lived families2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Pasquale C. Putter, Di Guan, Thies Gehrmann, Daniel Kolbe, Jiping Yang, HyeRim Han, +13 more
2citations -
ASP2998, a trophoblast cell-surface antigen 2 (TROP2)–targeted immunostimulatory antibody-drug conjugate with dual payloads, in patients with locally advanced unresectable or metastatic solid tumors: A phase 1b/2 study.
Guru Sonpavde, Martin Gutierrez, Anumeha Gupta, Shigehiro Koganemaru, Geraldine O’Sullivan Coyne, Jeffery Scott Russell, +8 more
0citations -
Salvianic Acid A-Loaded Layered Double Hydroxide Nanosheets Boost T-Cell Infiltration through Tumor Vascular Normalization for Enhanced Immunotherapy2026 ACS Biomaterials Science & Engineering article Engineering Nanoplatforms for cancer theranostics
Yuxi Xiang, Junyu Tan, Yunyun Wu, Chang YU, Daqing Xia, Jing Zhu, +2 more
0citations -
CD4+ T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors2024 Cellular and Molecular Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Xin Lei, Daniël de Groot, Marij J.P. Welters, Tom de Wit, Ellen Schrama, Hans van Eenennaam, +10 more
65citations -
Niraparib exhibits a synergistic anti-tumor effect with PD-L1 blockade by inducing an immune response in ovarian cancer2021 Journal of Translational Medicine article Medicine PARP inhibition in cancer therapy Open access cited by 1 patent
Jinyu Meng, Jin Peng, Jie Feng, Jochen Maurer, Xiao Li, Yan Li, +11 more
63citations -
Exploiting Synthetic Lethality between Germline BRCA1 Haploinsufficiency and PARP Inhibition in JAK2V617F-Positive Myeloproliferative Neoplasms2023 International Journal of Molecular Sciences article Medicine PARP inhibition in cancer therapy Open access
Max Bermes, María Jimena Rodriguez, Marcelo A. S. Toledo, Sabrina Ernst, Gerhard Müller‐Newen, Tim H. Brümmendorf, +3 more
7citations -
Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Vasculitis and related conditions Open access
Nina Kessler, Susanne F. Viehmann, Calvin Krollmann, Karola Mai, Katharina M. Kirschner, Hella Luksch, +20 more
7citations -
Immunostimulatory Profile of Cancer Cell Death by the AdV-Lumc007-Derived Oncolytic Virus ‘GoraVir’ in Cultured Pancreatic Cancer Cells2023 Viruses article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Selas T. F. Bots, Sanne L. Landman, Martijn J. W. E. Rabelink, Diana J.M. van den Wollenberg, Rob C. Hoeben
6citations