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Cutting Edge: Unconventional CD8+ T Cell Recognition of a Naturally Occurring HLA-A*02:01–Restricted 20mer Epitope2022 The Journal of Immunology article Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access
Miranda H. Meeuwsen, Anne K. Wouters, Renate S. Hagedoorn, Michel G.D. Kester, Dennis F.G. Remst, Dirk M. van der Steen, +6 more
3citations -
A minority of T cells recognizing tumor-associated antigens presented in self-HLA can provoke antitumor reactivity2020 Blood article Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 4 patents
Marthe C.J. Roex, Lois Hageman, Sabrina A.J. Veld, Esther van Egmond, Conny Hoogstraten, Christian Stemberger, +4 more
16citations -
Selection of a Single Domain Antibody, Specific for an HLA-Bound Epitope of the Mycobacterial Ag85B Antigen2020 Frontiers in Immunology article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 2 patents
Paola Andrea Ortega-Portilla, Mayra Silva‐Miranda, Alfredo Torres‐Larios, Eduardo Campos-Chávez, Kees L. M. C. Franken, Tom H. M. Ottenhoff, +2 more
8citations -
Magnitude of Off-Target Allo-HLA Reactivity by Third-Party Donor-Derived Virus-Specific T Cells Is Dictated by HLA-Restriction2021 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access cited by 1 patent
Wesley Huisman, Didier A.T. Leboux, Lieve E. van der Maarel, Lois Hageman, Derk Amsen, J.H. Frederik Falkenburg, +1 more
19citations -
Intradermal Naked DNA Vaccination by DNA Tattooing for Mounting Tumor-Specific Immunity in Stage IV Melanoma Patients: A Phase I Clinical Trial2024 Oncology Research and Treatment article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Marnix H. Geukes Foppen, Maartje W. Rohaan, Jessica S.W. Borgers, Daisy Philips, Florry A. Vyth‐Dreese, Jos H. Beijnen, +3 more
6citations -
TEIPP-vaccination in checkpoint-resistant non-small cell lung cancer: a first-in-human phase I/II dose-escalation study2025 Nature Communications article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Mitchell Emmers, Marij J.P. Welters, Michelle V. Dietz, Saskia J A M Santegoets, Sanne Boekesteijn, Anouk Stolk, +12 more
17citations -
HA-1H T-Cell Receptor Gene Transfer to Redirect Virus-Specific T Cells for Treatment of Hematological Malignancies After Allogeneic Stem Cell Transplantation: A Phase 1 Clinical Study
Peter van Balen, Inge Jedema, Marleen M. van Loenen, Renate de Boer, H.M. van Egmond, Renate S. Hagedoorn, +9 more
42citations -
Amino acids at position 5 in the peptide/MHC binding region of a public virus‐specific TCR are completely inter‐changeable without loss of function2022 European Journal of Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Wesley Huisman, Melanie de Gier, Lois Hageman, Alina S. Shomuradova, Didier A.T. Leboux, Derk Amsen, +2 more
3citations -
21P: Primary analysis of safety, efficacy and immunogenicity of the therapeutic cancer vaccine PDC*lung01 with or without pembrolizumab in NSCLC: A multicenter phase I/II study2025 Journal of Thoracic Oncology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
J.F. Vansteenkiste, I. Demedts, K. Cuppens, Elvire Pons Tostivint, E. Wauters, Frank Johannes Borm, +13 more
0citations -
A hot trick for efficient peptide exchange on MHC class I multimers for large-scale detection of antigen-specific T cells2022 Molecular Immunology article Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches
Jolien J. Luimstra, Malgorzata Anna Garstka, Jacques Neefjes, Huib Ovaa
0citations -
MHC Class I Stability is Modulated by Cell Surface Sialylation in Human Dendritic Cells2020 Pharmaceutics article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Zélia Silva, Tiago Ferro, D.S. Almeida, Helena Soares, José Alexandre Ferreira, Fanny M. Deschepper, +5 more
34citations -
T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes2021 Nature Biotechnology article Medicine CAR-T cell therapy research Open access cited by 7 patents
Muhammad Ali, Eirini Giannakopoulou, Yingqian Li, Madeleine Lehander, Stina Virding Culleton, Weiwen Yang, +27 more
36citations -
The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution2020 Nature Communications article Medicine Genetic factors in colorectal cancer Open access cited by 1 patent
Alexej Ballhausen, Moritz Jakob Przybilla, Michael Adrian Jendrusch, Saskia Haupt, Elisabeth Pfaffendorf, Florian Seidler, +24 more
138citations -
Human islet T cells are highly reactive to preproinsulin in type 1 diabetes2021 Proceedings of the National Academy of Sciences article Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access cited by 1 patent
Amanda M. Anderson, Laurie G. Landry, Aimon K. Alkanani, Laura L. Pyle, Alvin C. Powers, Mark A. Atkinson, +4 more
96citations -
Generation of effective and specific human TCRs against tumor/testis antigen NY-ESO-1 in mice with humanized T cell recognition system2024 Frontiers in Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Xiaojing Tina Chen, Matthias Leisegang, Ioannis Gavvovidis, Seth M. Pollack, Felix K.M. Lorenz, Ton N. Schumacher, +2 more
6citations -
Treatment sequence with tebentafusp and immune checkpoint inhibitors in patients with metastatic uveal melanoma and metastatic GNA11/GNAQ mutant melanocytic tumors2025 Leiden Repository (Leiden University) article Medicine Ocular Oncology and Treatments Open access
Florentia; https://orcid.org/0000-0003-4529-3372 Dimitriou, Marlana M. Orloff, Erica C. Koch Hein, P.F. Cheng, Isaac F Hughes, Ester Simeone, +18 more
1citations -
1018P Characterization of liver function tests following tebentafusp in phase III randomized trial comparing tebentafusp with investigator’s choice in first line metastatic uveal melanoma (mUM)
Bartosz Chmielowski, Ellen Kapiteijn, Paolo A. Ascierto, Friedegund Elke Meier, Shaad Essa Abdullah, Patricia Méndez, +1 more
1citations
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