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Hotspot DNA Methyltransferase 3A (DNMT3A) and Isocitrate Dehydrogenase 1 and 2 (IDH1/2) Mutations in Acute Myeloid Leukemia and Their Relevance as Targets for Immunotherapy
Nadine E. Struckman, Rob C. M. de Jong, M. Willy Honders, Sophie-Anne I. Smith, Dyantha I. van der Lee, Georgia Koutsoumpli, +5 more
7citations -
Mutated DNMT3A creates a public HLADQ- binding neoantigen on acute myeloid leukemia2025 Frontiers in Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Dyantha I. van der Lee, Eva M. Argiro, Sebastiaan N. J. Laan, M. Willy Honders, Rob C. M. de Jong, Nadine Struckman, +2 more
3citations -
Hematopoietic differentiation persists in human iPSCs defective in de novo DNA methylation2022 BMC Biology article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access cited by 2 patents
Olivia Cypris, Julia Franzen, Joana Frobel, Philipp Glück, Chao‐Chung Kuo, Stephani Schmitz, +3 more
10citations -
Epigenomics Nutritional Insights of Crocus sativus L.: Computational Analysis of Bioactive Molecules Targeting DNA Methyltransferases and Histone Deacetylases2025 International Journal of Molecular Sciences article Medicine Saffron Plant Research Studies Open access
Alessia Piergentili, Paolo Roberto Saraceni, Olivia Costantina Demurtas, Barbara Benassi, Caterina Arcangeli
0citations -
Clonal Hematopoiesis–Associated Gene Mutations in a Clinical Cohort of 448 Patients With Ovarian Cancer2021 JNCI Journal of the National Cancer Institute article Medicine Acute Myeloid Leukemia Research Open access
Konstantin Weber‐Lassalle, Corinna Ernst, Alexander Reuß, Kathrin Möllenhoff, Klaus Baumann, Christian Jackisch, +16 more
38citations -
A human somatic cell culture system for modelling gene silencing by transcriptional interference2020 Heliyon article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access cited by 1 patent
Theresa Kühnel, Helena Heinz, Nadja Utz, Tanja Božić, Bernhard Horsthemke, Laura Steenpaß
5citations -
NSD1 governs H3K36me2-mediated DNA methylation and drives endo-mesodermal differentiation of human iPSCs2026 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Anna Hansknecht, Martina Mankarious, Monica Varona Baranda, Esra Dursun Torlak, Wolfgang Wagner, Kira Zeevaert, +1 more
0citations -
A perspective on causality assessment in epigenetic research on neurodegenerative disorders2022 Neural Regeneration Research article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Philippos Koulousakis, Assia Tiane, Niels Hellings, Jos Prickaerts, Daniël van den Hove, Tim Vanmierlo
8citations -
Genetic and Epigenetic Changes at Secondary Resistance after Continued Treatment in the Randomized Phase II Study of All-Trans Retinoic Acid (ATRA) and/or Valproic Acid (VPA) Added to Decitabine (DAC) in Newly Diagnosed Elderly AML Patients (DECIDER Trial)
Inga Hund, Maria Elena Hess, Julia Stomper, Gabriele Greve, Jan Mitschke, Christoph Niemöller, +13 more
0citations
17 results