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Uncoupling DNA damage from chromatin damage to detoxify doxorubicin2020 Proceedings of the National Academy of Sciences article Biochemistry, Genetics and Molecular Biology Cancer therapeutics and mechanisms Open access
Xiaohang Qiao, Sabina Y. van der Zanden, Dennis P. A. Wander, Daniel Borràs, Ji‐Ying Song, Xiaoyang Li, +21 more
177citations -
Unscheduled DNA Synthesis at Sites of Local UV-induced DNA Damage to Quantify Global Genome Nucleotide Excision Repair Activity in Human Cells2023 BIO-PROTOCOL article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Paula J. van der Meer, Diana van den Heuvel, Martijn S. Luijsterburg
12citations -
Nucleotide excision repair leaves a mark on chromatin: DNA damage detection in nucleosomes2021 Cellular and Molecular Life Sciences article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Katja Apelt, Hannes Lans, Orlando D. Schärer, Martijn S. Luijsterburg
43citations -
The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II2020 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Yana van der Weegen, Hadar Golan-Berman, Tycho E.T. Mevissen, Katja Apelt, Román González‐Prieto, Joachim Goedhart, +6 more
185citations -
XPC–PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair2022 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Charlotte Blessing, Katja Apelt, Diana van den Heuvel, Claudia Gonzalez-Leal, Magdalena B. Rother, Melanie van der Woude, +16 more
28citations -
CIP2A interacts with TopBP1 and is selectively essential for DNA damage-induced basal-like breast cancer tumorigenesis2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Anni Laine, Srikar Goud Nagelli, Caroline C. Farrington, Umar Butt, Anna N. Cvrljevic, Julia P. Vainonen, +17 more
2citations -
In Vitro Three‐Dimensional Liver Models for Nanomaterial DNA Damage Assessment2021 Small article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Samantha V. Llewellyn, Marije Niemeijer, Penny E. H. Nymark, Martijn J. Moné, Bob van de Water, Gillian E. Conway, +2 more
49citations -
Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities2026 Angewandte Chemie International Edition article Medicine Microbial Natural Products and Biosynthesis Open access
Rongbin Wang, Heli Tirkkonen, Sabina Y. van der Zanden, Larissa Ponomareva, Isaline Fagon, Leslie Fève, +10 more
0citations -
PAF1C restores transcription after DNA damage independently of promoting histone mark deposition2026 EMBO Reports article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Janne J. M. van Schie, Bram A F J de Groot, Diana van den Heuvel, Martijn S. Luijsterburg
2citations -
SENP6 regulates localization and nuclear condensation of DNA damage response proteins by group deSUMOylation2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Laura A. Claessens, Matty Verlaan–de Vries, Ilona J. de Graaf, Alfred C.O. Vertegaal
35citations -
Chemo-Phosphoproteomic Profiling with ATR Inhibitors Berzosertib and Gartisertib Uncovers New Biomarkers and DNA Damage Response Regulators2024 Molecular & Cellular Proteomics article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Rathan S Jadav, Florian Weiland, Sylvie M. Noordermeer, Thomas D. Carroll, Yuandi Gao, Jianming Wang, +11 more
8citations -
Poly-(ADP-ribose) serves as a scaffold for the methyltransferase METTL3/14 complex in the DNA damage response2025 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Claudia Gonzalez-Leal, Jin Cai, Bram A F J de Groot, Andreas Wegerer, Julia Preißer, Martijn S. Luijsterburg, +1 more
5citations -
PAF1C-driven restoration of RNAPII elongation after DNA damage occurs independently of transcription-associated histone mark deposition2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genomics and Chromatin Dynamics Open access
Janne J. M. van Schie, Bram A F J de Groot, Martijn S. Luijsterburg
0citations -
The translocated virulence protein VirD5 causes DNA damage and mutation during Agrobacterium -mediated transformation of yeast2022 Science Advances article Biochemistry, Genetics and Molecular Biology Fungal and yeast genetics research Open access
Xiaorong Zhang, Marjolein J. G. Hooykaas, Gerard Paul H. van Heusden, Paul J. J. Hooykaas
8citations -
Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells2025 Molecular Oncology article Biochemistry, Genetics and Molecular Biology Chromatin Remodeling and Cancer Open access
R. Schlosser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, +6 more
2citations -
Spatio-temporal transcriptomic analysis reveals distinct nephrotoxicity, DNA damage, and regeneration response after cisplatin2025 Cell Biology and Toxicology article Medicine Chemotherapy-induced organ toxicity mitigation Open access
Lukas S. Wijaya, Steven J. Kunnen, Panuwat Trairatphisan, Ciaran P. Fisher, Meredith E. Crosby, Kai Schaefer, +11 more
11citations -
Towards an advanced testing strategy for genotoxicity using image-based 2D and 3D HepG2 DNA damage response fluorescent protein reporters2021 Mutagenesis article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Bas ter Braak, Marije Niemeijer, Liesanne Wolters, Sylvia E. Le Dévédec, Peter Bouwman, Bob van de Water
6citations -
Computational modelling identifies primary mediators of crosstalk between DNA damage and oxidative stress responses2025 PLoS Computational Biology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Elsje J Burgers, Raju P. Sharma, Carl Joshua Eugenio, Muriel M. Heldring, Lukas S. Wijaya, Bob van de Water, +1 more
3citations