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Lower Dose‐Normalized Tacrolimus Exposure in CYP3A5 *6 vs. *3 Loss‐of‐Function Allele Carriers: A Longitudinal Retrospective Real‐World Study in Kidney Transplant Recipients2025 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Amar D. Levens, Dirk Jan A. R. Moes, Yanick Boer, Aiko P. J. de Vries, Dorottya K. de Vries, Danny van der Helm, +5 more
5citations -
The Clinical Impact of the C0/D Ratio and the CYP3A5 Genotype on Outcome in Tacrolimus Treated Kidney Transplant Recipients2020 Frontiers in Pharmacology article Medicine Renal Transplantation Outcomes and Treatments Open access
Teun van Gelder, Soufian Meziyerh, Jesse Joachim Swen, Aiko P. J. de Vries, Dirk Jan A. R. Moes
72citations -
Comparison of the Impact of Pharmacogenetic Variability on the PK of Slow Release and Immediate Release Tacrolimus Formulations2020 Genes article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Teun van Gelder, Oumaima Etsouli, Dirk Jan A. R. Moes, Jesse Joachim Swen
9citations -
A Population Pharmacokinetic Model and Dosing Algorithm to Guide the Tacrolimus Starting and Follow-Up Dose in Living and Deceased Donor Kidney Transplant Recipients2025 Clinical Pharmacokinetics article Medicine Renal Transplantation Outcomes and Treatments Open access
Marith I. Francke, Sebastiaan D. T. Sassen, Núria Lloberas, Helena Colom, Laure Elens, Serge Moudio, +5 more
8citations -
Mapping the Pharmacogenetic Landscape in a Ugandan Population: Implications for Personalized Medicine in an Underrepresented Population2024 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sumudu Rangika Samarasinghe, Seung‐been Lee, Manuel Corpas, Segun Fatumo, Henk‐Jan Guchelaar, Shivashankar Hiriyur Nagaraj
8citations -
Editorial: Innovations in pharmacogenomics: embracing diversity and clinical application2026 Frontiers in Pharmacology editorial Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Maaike van der Lee, Sarah Cargnin, Elena Peruzzi, Claudia Pisanu, Rossana Roncato
0citations -
Avoiding Tacrolimus Underexposure and Overexposure with a Dosing Algorithm for Renal Transplant Recipients: A Single Arm Prospective Intervention Trial2021 Clinical Pharmacology & Therapeutics article Medicine Renal Transplantation Outcomes and Treatments Open access
Marith I. Francke, Louise M. Andrews, Hoang Lan Le, Jacqueline van de Wetering, Marian C. Clahsen‐van Groningen, Teun van Gelder, +4 more
44citations -
Population pharmacokinetics and genetics of oral meltdose tacrolimus (Envarsus) in stable adult liver transplant recipients2021 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Lisa C. Martial, Maaike Biewenga, Bastian N. Ruijter, Ron J. Keizer, Jesse Joachim Swen, Bart van Hoek, +1 more
19citations -
Towards precision dosing of aripiprazole in children and adolescents with autism spectrum disorder: Linking blood levels to weight gain and effectiveness2023 British Journal of Clinical Pharmacology article Medicine Pharmaceutical studies and practices Open access
Rebecca A. Hermans, Sebastiaan D. T. Sassen, Sanne Maartje Kloosterboer, Catrien G. Reichart, Mirjam E. J. Kouijzer, Matthias M. J. de Kroon, +8 more
8citations -
685P Genome-wide association meta-analysis identifies novel variants that correlate with efficacy outcomes in sunitinib-treated patients with metastatic renal cell carcinoma
Meta H.M. Diekstra, Jesse Joachim Swen, L. van der Zanden, Epic Boven, Ron H.J. Mathijssen, Arna Óskarsdóttir, +13 more
0citations -
Physiologically based pharmacokinetic modeling of tacrolimus for food–drug and CYP3A drug–drug–gene interaction predictions2023 CPT Pharmacometrics & Systems Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Helena Leonie Hanae Loer, Denise Feick, Simeon Rüdesheim, Dominik Selzer, Matthias Georg Schwab, Donato Teutonico, +5 more
22citations -
Concomitant use of isavuconazole and CYP3A4/5 inducers: Where pharmacogenetics meets pharmacokinetics2021 Mycoses article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Ruth Van Daele, Yves A. Debaveye, Robin Vos, Pascal Van Bleyenbergh, Roger J. M. Brüggemann, Erwin Dreesen, +5 more
11citations -
Extended-Release Tacrolimus Versus LifeCycle Pharma Tacrolimus in Kidney Transplant Recipients: A Switch Study2026 Therapeutic Drug Monitoring article Medicine Renal Transplantation Outcomes and Treatments Open access
Emma H. van Schijndel, Theodora Standaar, Marloes van der Meer‐Vos, Liffert Vogt, Ron A. A. Mathôt, Jesse Joachim Swen, +4 more
0citations -
Risperidone plasma concentrations are associated with side effects and effectiveness in children and adolescents with autism spectrum disorder2020 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sanne Maartje Kloosterboer, Brenda C. M. de Winter, Catrien G. Reichart, Mirjam E. J. Kouijzer, Matthias M. J. de Kroon, Emma van Daalen, +11 more
80citations -
Ontogeny of Small Intestinal Drug Transporters and Metabolizing Enzymes Based on Targeted Quantitative Proteomics2021 Drug Metabolism and Disposition article Medicine Drug Transport and Resistance Mechanisms Open access
Márton Kiss, Richard J. Mbasu, Johan Nicolaï, Karin Barnouin, Apoorva Kotian, Miriam G. Mooij, +6 more
45citations -
Model-Based Tacrolimus Follow-up Dosing in Adult Renal Transplant Recipients: A Simulation Trial2022 Therapeutic Drug Monitoring article Medicine Renal Transplantation Outcomes and Treatments Open access
Marith I. Francke, Dennis Alexander Hesselink, Louise M. Andrews, Teun van Gelder, Ron J. Keizer, Brenda C. M. de Winter
13citations -
Genome-Wide Meta-Analysis Identifies Variants in DSCAM and PDLIM3 That Correlate with Efficacy Outcomes in Metastatic Renal Cell Carcinoma Patients Treated with Sunitinib
Meta H.M. Diekstra, Jesse Joachim Swen, Loes F.M. van der Zanden, Sita H. H. M. Vermeulen, Epie Boven, Ron H.J. Mathijssen, +20 more
7citations -
Effect of CYP3A4 Methylation on Tacrolimus Pharmacokinetics2025 Therapeutic Drug Monitoring article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Karel K. M. Koudijs, Oumaima Etsouli, Costanza Ludovica Vallerga, Dirk Jan A. R. Moes, Bastian N. Ruijter, Jesse Joachim Swen, +2 more
2citations -
Design and performance of a long-read sequencing panel for pharmacogenomics2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Maaike van der Lee, Loes Busscher, Roberta Menafra, Qinglian Zhai, Redmar R. van den Berg, Sarah B. Kingan, +6 more
2citations
22 results