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Inflammation altered correlation between CYP2C19 genotype and CYP2C19 activity in patients receiving voriconazole2024 Clinical and Translational Science article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sylvia D. Klomp, Anette Veringa, Jan‐Willem C. Alffenaar, Mark G. J. de Boer, Lambert F. R. Span, Henk‐Jan Guchelaar, +1 more
15citations -
The impact of CYP2C19 genotype on phenoconversion by concomitant medication2023 Frontiers in Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Laura M. de Jong, Soukayna Boussallami, Martin A. Giera, Maarten E. Tushuizen, Menno Hoekstra, Lukas J.A.C. Hawinkels, +3 more
31citations -
Subtherapeutic bupropion and hydroxybupropion serum concentrations in a patient with CYP2C19*1/*17 genotype suggesting a rapid metabolizer status2020 The Pharmacogenomics Journal article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism
Arnim Johannes Gaebler, Katharina Luise Schneider, Julia Stingl, Michael Paulzen
3citations -
Feasibility of Community Pharmacist-Initiated and Point-of-Care CYP2C19 Genotype-Guided De-Escalation of Oral P2Y12 Inhibitors2023 Genes article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Amar D. Levens, Melina C. den Haan, J. Wouter Jukema, Mette Heringa, Wilbert B. van den Hout, Dirk Jan A. R. Moes, +1 more
11citations -
Clopidogrel in noncarriers of CYP2C19 loss-of-function alleles versus ticagrelor in elderly patients with acute coronary syndrome: A pre-specified sub analysis from the POPular Genetics and POPular Age trials CYP2C19 alleles in elderly patients2021 International Journal of Cardiology article Medicine Antiplatelet Therapy and Cardiovascular Diseases Open access
Daniel M.F. Claassens, Marieke E. Gimbel, Thomas O. Bergmeijer, Gerrit J.A. Vos, Renicus Suffridus Hermanides, Pim van der Harst, +19 more
9citations -
Combined effect of CYP2C19 and CYP2D6 genotypes on escitalopram serum concentration and its metabolic ratio in a European patient population2024 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Pari Faraj, Tore Haslemo, Jenny Phung Tran, Julia Stingl, Espen Molden, Kristine Hole
7citations -
The role of the poor metabolizer genotype CYP2D6 and CYP1A2 phenotype in the pharmacokinetics of duloxetine and venlafaxine—A case report2020 Basic & Clinical Pharmacology & Toxicology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism
Isabel Scharrer, Daniele Nolan, Markus R. Baumgartner, Michael Paulzen, Georgios Schoretsanitis, Franziskos Xepapadakos
6citations -
From gene to dose: Long-read sequencing and *-allele tools to refine phenotype predictions of CYP2C192023 Frontiers in Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Lonneke J. Graansma, Qinglian Zhai, Loes Busscher, Roberta Menafra, Redmar R. van den Berg, Susan L. Kloet, +1 more
17citations -
Genotype-Guided Antiplatelet Therapy2024 Journal of the American College of Cardiology article Medicine Antiplatelet Therapy and Cardiovascular Diseases Open access
Wout W. A. van den Broek, Brenden S. Ingraham, Naveen L. Pereira, Craig R. Lee, Larisa H. Cavallari, Jesse Joachim Swen, +2 more
21citations -
Effect of CYP2C19 genotypes on tamoxifen metabolism and early-breast cancer relapse2021 Scientific Reports article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Anabel Sanchez‐Spitman, Jesse Joachim Swen, Vincent Olaf Dezentjé, Dirk Jan A. R. Moes, Hans A. J. Gelderblom, Henk‐Jan Guchelaar
15citations -
Long‐Read Sequencing Enhances Pharmacogenomic Profiling by Resolving Complex Haplotypes, Novel Star Alleles, and Structural Variants2025 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism
Sumudu Rangika Samarasinghe, Andrea Gaedigk, Jesse Joachim Swen, Henk‐Jan Guchelaar, Shivashankar Hiriyur Nagaraj
3citations -
Development of a dosing algorithm integrating pharmacogenetic markers and inflammation for individualization of initial voriconazole maintenance doses2026 Antimicrobial Agents and Chemotherapy article Medicine Antifungal resistance and susceptibility Open access
Elodie Gautier‐Veyret, Othilie Giannoni, Marc Manceau, Capucine Arrivé, Sylvia D. Klomp, Matthieu Roustit, +15 more
0citations -
Editorial: Innovations in pharmacogenomics: embracing diversity and clinical application2026 Frontiers in Pharmacology editorial Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Maaike van der Lee, Sarah Cargnin, Elena Peruzzi, Claudia Pisanu, Rossana Roncato
0citations -
Policy and Practice Review: A First Guideline on the Use of Pharmacogenetics in Clinical Psychiatric Practice2021 Frontiers in Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Roos van Westrhenen, Ron H. N. van Schaik, Teun van Gelder, Tom K. Birkenhäger, Pieter Roberto Bakker, Elisa J. F. Houwink, +3 more
43citations -
Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing2020 Clinical Pharmacokinetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Anyue Yin, Madeleine H. T. Ettaieb, Jesse Joachim Swen, Liselotte van Deun, Thomas M. A. Kerkhofs, R.J.H.M. van der Straaten, +11 more
13citations -
Association of Polymorphic Cytochrome P450 Enzyme Pathways with Falls in Multimedicated Older Adults2024 Journal of the American Medical Directors Association article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Katja Susanne Just, Laura M. Pott, Catharina Scholl, Michael Steffens, Michael Dieter Denkinger, Dietrich Rothenbacher, +2 more
4citations -
Inflammation‐driven variability in drug metabolism: Insights from voriconazole treatment of HSCT recipients2026 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sylvia D. Klomp, Martijn L. Manson, Henk‐Jan Guchelaar, Stefan Böhringer, Esther H.M. van Egmond, Peter A. von dem Borne, +1 more
2citations -
The pharmacogenomic landscape of an Indigenous Australian population2023 Frontiers in Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sumudu Rangika Samarasinghe, Wendy E. Hoy, Sudhir Jadhao, Brendan John McMorran, Henk‐Jan Guchelaar, Shivashankar Hiriyur Nagaraj
14citations