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Inflammation altered correlation between CYP2C19 genotype and CYP2C19 activity in patients receiving voriconazole2024 Clinical and Translational Science article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sylvia D. Klomp, Anette Veringa, Jan‐Willem C. Alffenaar, Mark G. J. de Boer, Lambert F. R. Span, Henk‐Jan Guchelaar, +1 more
15citations -
Clopidogrel in noncarriers of CYP2C19 loss-of-function alleles versus ticagrelor in elderly patients with acute coronary syndrome: A pre-specified sub analysis from the POPular Genetics and POPular Age trials CYP2C19 alleles in elderly patients2021 International Journal of Cardiology article Medicine Antiplatelet Therapy and Cardiovascular Diseases Open access
Daniel M.F. Claassens, Marieke E. Gimbel, Thomas O. Bergmeijer, Gerrit J.A. Vos, Renicus Suffridus Hermanides, Pim van der Harst, +19 more
9citations -
Effect of CYP2C19 genotypes on tamoxifen metabolism and early-breast cancer relapse2021 Scientific Reports article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Anabel Sanchez‐Spitman, Jesse Joachim Swen, Vincent Olaf Dezentjé, Dirk Jan A. R. Moes, Hans A. J. Gelderblom, Henk‐Jan Guchelaar
15citations -
Subtherapeutic bupropion and hydroxybupropion serum concentrations in a patient with CYP2C19*1/*17 genotype suggesting a rapid metabolizer status2020 The Pharmacogenomics Journal article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism
Arnim Johannes Gaebler, Katharina Luise Schneider, Julia Stingl, Michael Paulzen
3citations -
The impact of CYP2C19 genotype on phenoconversion by concomitant medication2023 Frontiers in Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Laura M. de Jong, Soukayna Boussallami, Martin A. Giera, Maarten E. Tushuizen, Menno Hoekstra, Lukas J.A.C. Hawinkels, +3 more
31citations -
Combined effect of CYP2C19 and CYP2D6 genotypes on escitalopram serum concentration and its metabolic ratio in a European patient population2024 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Pari Faraj, Tore Haslemo, Jenny Phung Tran, Julia Stingl, Espen Molden, Kristine Hole
7citations -
Evaluation of a pantoprazole and 4‐desmethylpantoprazole‐sulfate metabolic ratio as a novel CYP2C19 phenotyping method2026 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Julian Peter Müller, Vladimir N. Belov, Sabrina Yamoune, Bob Miller, Mohammed Hasoumi, Jolanta Tupiec, +4 more
1citations -
Feasibility of Community Pharmacist-Initiated and Point-of-Care CYP2C19 Genotype-Guided De-Escalation of Oral P2Y12 Inhibitors2023 Genes article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Amar D. Levens, Melina C. den Haan, J. Wouter Jukema, Mette Heringa, Wilbert B. van den Hout, Dirk Jan A. R. Moes, +1 more
11citations -
From gene to dose: Long-read sequencing and *-allele tools to refine phenotype predictions of CYP2C192023 Frontiers in Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Lonneke J. Graansma, Qinglian Zhai, Loes Busscher, Roberta Menafra, Redmar R. van den Berg, Susan L. Kloet, +1 more
17citations -
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2C19 and CYP2D6 and SSRIs2021 European Journal of Human Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
J. Brouwer, Marga Nijenhuis, Bianca Soree, Henk‐Jan Guchelaar, Jesse Joachim Swen, Ron H. N. van Schaik, +9 more
135citations -
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6, CYP2C19 and non-SSRI/non-TCA antidepressants2024 European Journal of Human Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Lianne Beunk, Marga Nijenhuis, Bianca Soree, Nienke J. de Boer‐Veger, Anne‐Marie Buunk, Henk‐Jan Guchelaar, +8 more
24citations -
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene–drug interaction between CYP2D6 and CYP2C19 and tricyclic antidepressants2026 European Journal of Human Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Kristian Kleine Schaars, Marga Nijenhuis, Bianca Soree, Nienke J. de Boer‐Veger, Anne‐Marie Buunk, Henk‐Jan Guchelaar, +8 more
8citations -
Stereoselective Determination of Omeprazole and 5‐Hydroxy‐Omeprazole in Dried Blood Spots for CYP2C19 Activity Assessment2026 Basic & Clinical Pharmacology & Toxicology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Toon Hectors, Kenza Abouir, Emmanuel Varesio, Martijn L. Manson, Youssef Daali, Caroline Flora Samer
0citations -
Association of Polymorphic Cytochrome P450 Enzyme Pathways with Falls in Multimedicated Older Adults2024 Journal of the American Medical Directors Association article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Katja Susanne Just, Laura M. Pott, Catharina Scholl, Michael Steffens, Michael Dieter Denkinger, Dietrich Rothenbacher, +2 more
4citations -
Inflammation‐driven variability in drug metabolism: Insights from voriconazole treatment of HSCT recipients2026 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sylvia D. Klomp, Martijn L. Manson, Henk‐Jan Guchelaar, Stefan Böhringer, Esther H.M. van Egmond, Peter A. von dem Borne, +1 more
2citations -
Adverse Drug Reactions in the Emergency Department: Is There a Role for Pharmacogenomic Profiles at Risk?—Results from the ADRED Study2020 Journal of Clinical Medicine article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Katja Susanne Just, Harald Dormann, Marlen Schurig, Miriam Böhme, Jochen Fracowiak, Michael Steffens, +5 more
19citations