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CRISPR/Cas9 mediated CXCL4 knockout in human iPS cells of polycythemia vera patient with JAK2 V617F mutation2021 Stem Cell Research article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Janik Boehnke, Salim Atakhanov, Marcelo A. S. Toledo, Herdit M. Schüler, Stephanie Sontag, Nicolas Chatain, +4 more
2citations -
CRISPR/Cas9 editing in conditionally immortalized HoxB8 cells for studying gene regulation in mouse dendritic cells2021 European Journal of Immunology article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Huaming Xu, Thomas A. Look, Sujeethkumar Prithiviraj, Daniel Lennartz, Manuel Delgado Cáceres, Katrin Götz, +5 more
13citations -
Construction of an Aspergillus oryzae triple amylase deletion mutant as a chassis to evaluate industrially relevant amylases using multiplex CRISPR/Cas9 editing technology5citations
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Automated CRISPR/Cas9-based genome editing of human pluripotent stem cells using the StemCellFactory2024 Frontiers in Bioengineering and Biotechnology article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Bastian Nießing, Yannik Breitkreuz, Andreas Elanzew, Marcelo A. S. Toledo, P. Vajs, M. Nolden, +9 more
8citations -
Guidelines for mouse and human DC generation2022 European Journal of Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 2 patents
Manfred Bernhard Lutz, Shafaqat Ali, Cindy Audiger, Stella E. Autenrieth, Luciana Berod, Venetia Bigley, +20 more
59citations -
Drosophila melanogaster as a versatile model organism to study genetic epilepsies: An overview2023 Frontiers in Molecular Neuroscience article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Florian P. Fischer, Robin A. Karge, Yvonne G. Weber, Henner Koch, Stefan Wolking, Aaron Voigt
49citations -
AutoBioTech─A Versatile Biofoundry for Automated Strain Engineering2024 ACS Synthetic Biology article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Tobias Michael Rosch, Julia Tenhaef, Till Redeker, Dominic Kösters, Niels Hollmann, Karin Krumbach, +5 more
36citations -
A comprehensive overview of CRISPR/Cas 9 technology and application thereof in drug discovery2022 Journal of Cellular Biochemistry article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Amit Khurana, Nilofer Sayed, Vishakha Singh, Isha Khurana, Prince Allawadhi, Pushkar Singh Rawat, +4 more
22citations -
Enhancing stability of recombinant CHO cells by CRISPR/Cas9-mediated site-specific integration into regions with distinct histone modifications2022 Frontiers in Bioengineering and Biotechnology article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access cited by 4 patents
Oliver Hertel, Anne Neuß, Tobias Busche, David Brandt, Jörn Kalinowski, Janina Bahnemann, +1 more
20citations -
Revolutionizing liver fibrosis research: the promise of 3D organoid models in understanding and treating chronic liver disease2025 Expert Review of Gastroenterology & Hepatology article Medicine Liver physiology and pathology Open access
Umashanker Navik, Sumeet Kumar Singh, Amit Khurana, Ralf Weiskirchen
7citations -
The pain target NaV1.7 is expressed late during human iPS cell differentiation into sensory neurons as determined in high-resolution imaging2024 Pflügers Archiv - European Journal of Physiology article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Yi Liu, Rachna Balaji, Marcelo A. S. Toledo, Sabrina Ernst, Petra A. I. Hautvast, Aylin Bilge Kesdoğan, +4 more
4citations -
Development of a telomere vector‐based approach to overcome limitations caused by lethal phenotypes in the study of essential genes in Magnaporthe oryzae2024 Molecular Plant Pathology article Biochemistry, Genetics and Molecular Biology Plant Pathogens and Fungal Diseases Open access
Louisa Wirtz, Florencia Casanova, Ulrich Schaffrath, Alex Wegner
3citations -
The pain target NaV1.7 is expressed late during human iPS cell differentiation into sensory neurons as determined in high resolution imaging2023 Research Square preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Yi Liu, Rachna Balaji, Marcelo A. S. Toledo, Sabrina Ernst, Petra A. I. Hautvast, Martin Zenke, +2 more
0citations -
Human Induced Pluripotent Stem Cell-Derived Kidney Organoids to Model Idiopathic and Congenital Nephrotic Syndrome2021 Journal of the American Society of Nephrology conference-abstract Biochemistry, Genetics and Molecular Biology Renal and related cancers
Jitske Jansen, Bartholomeus T. van den Berge, Martijn van den Broek, Brigith K. Willemsen, Christoph Kuppe, Gianluca V. Di Giovanni, +10 more
0citations -
CRISPR-Induced Knockout of Ubiquitin Ligase Cullin 3 in Human Proximal Tubule Cells2021 Journal of the American Society of Nephrology conference-abstract Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways
Turgay Saritas, Lu Chen, Susanne Maria Ziegler, Nazanin Kabgani, Christoph Kuppe, Jürgen Floege, +2 more
0citations