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Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL2024 The Journal of Experimental Medicine article Medicine Lymphoma Diagnosis and Treatment Open access
Janneke A. Eken, Marvyn T. Koning, Kristýna Kupcová, Julieta Sepúlveda-Yáñez, Ruben A. L. de Groen, Edwin Quinten, +10 more
19citations -
N-linked Fc glycosylation is not required for IgG-B-cell receptor function in a GC-derived B-cell line2024 Nature Communications article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Theresa Kissel, Veerle F. A. M. Derksen, Arthur E. H. Bentlage, Carolien A. M. Koeleman, Lise Hafkenscheid, Diane van der Woude, +3 more
11citations -
Disease activity and anti-topoisomerase I antibody positivity are associated with elevated serum B cell activating factor levels and a B cell subset-wide reduction of BAFF-receptor expression in SSc
A M Alzahrani, Stefan F. H. Neys, Wieke M. van Oostveen, Saad Ahmed, E W N Levarht, Rudi W. Hendriks, +5 more
0citations -
Autonomous B-cell receptor signaling and genetic aberrations in chronic lymphocytic leukemia-phenotype monoclonal B lymphocytosis in siblings of patients with chronic lymphocytic leukemia
Edwin Quinten, Julieta Sepúlveda-Yáñez, Marvyn T. Koning, Janneke A. Eken, Dietmar Pfeifer, Valeri Nteleah, +15 more
11citations -
Site-specific profiling of structure and function of Igµ B cell receptor glycans2026 Nature Communications article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Miles D. Holborough-Kerkvliet, Lise Hafkenscheid, Sanne Kroos, Roxane Biersteker, Ojas Singh, Elisa Fadda, +5 more
1citations -
Chemokine–receptor-guided B-cell immunity in cardiovascular disease2025 Basic Research in Cardiology article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Anaïs Yerly, Emiel P. C. van der Vorst, Marc Schindewolf, Drosos Kotelis, Heidi Noels, Yvonne Döring
9citations -
Benchmarking computational methods for B-cell receptor reconstruction from single-cell RNA-seq data2022 NAR Genomics and Bioinformatics article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Tommaso Andreani, Linda M. Slot, Samuel Gabillard, Carsten Strübing, Yaligara Veeranagouda, Aleida M. Bakker, +5 more
14citations -
Aberrant intra‐epithelial lymphocytes cause enterocyte cell death in refractory celiac disease by CD103 ‐β7‐receptor‐mediated granzyme‐B degranulation which can be restored by etrolizumab2026 Clinical & Translational Immunology article Medicine Celiac Disease Research and Management Open access
Daan A R Castelijn, Jolanda MW van de Water, Laura R. de Baaij, Bridget S McGlinchy, Michelle van Leeuwen, Sander P.J. Joosten, +13 more
1citations -
Gut T cell–independent IgA responses to commensal bacteria require engagement of the TACI receptor on B cells2020 Science Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Emilie K. Grasset, Alejo Chorny, Sandra Casas-Recasens, Cindy Gutzeit, Gerold Bongers, Irene Thomsen, +19 more
86citations -
Templated insertions at VD and DJ junctions create unique B‐cell receptors in the healthy B‐cell repertoire2020 European Journal of Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Marvyn T. Koning, Esther M. Vletter, Rik Rademaker, Rochelle D. Vergroesen, I. Trollmann, Paul W.H.I. Parren, +5 more
4citations -
Light chain skewing in autoantibodies and B-cell receptors of the citrullinated antigen-binding B-cell response in rheumatoid arthritis2021 PLoS ONE article Medicine Rheumatoid Arthritis Research and Therapies Open access cited by 1 patent
Linda M. Slot, Rochelle D. Vergroesen, Priscilla F. Kerkman, Ellen Magadalena Staudinger, Sanne Reijm, Hugo J. van Dooren, +4 more
9citations -
Emerging Immune Cell Biomarkers in Primary Membranous Nephropathy: Immune Cell Profiling During Anti-CD20 B Cell-Targeted Therapy2026 International Journal of Molecular Sciences article Medicine Renal Diseases and Glomerulopathies Open access
Christos Georgopoulos, Eleni Stamellou, Αnila Duni, Lefkothea Dova, George Vartholomatos, Ekaterini C. Siomou, +2 more
0citations -
Variable domain glycosylation as a marker and modulator of immune responses: Insights into autoimmunity and B-cell malignancies2025 Seminars in Immunology article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Roxane Biersteker, Manfred Wuhrer, Tom W. J. Huizinga, René E. M. Toes, Lise Hafkenscheid
5citations -
Effect of Antigen Valency on Autoreactive B-Cell Targeting2023 Molecular Pharmaceutics article Medicine Rheumatoid Arthritis Research and Therapies Open access
Margot J. van Weijsten, Kevin R. Venrooij, Lianne P. W. M. Lelieveldt, Theresa Kissel, Erik van Buijtenen, Floris J. van Dalen, +3 more
4citations -
Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation2022 Science Advances article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Theresa Kissel, Changrong Ge, Lise Hafkenscheid, Joanneke C. Kwekkeboom, Linda M. Slot, Marco Cavallari, +18 more
77citations -
Dual dynamics of persistence and recruitment characterise the ACPA-expressing B cell response in rheumatoid arthritis2026 Annals of the Rheumatic Diseases article Medicine Rheumatoid Arthritis Research and Therapies Open access
Renee van de Wetering, Shachi Mujumdar, Linda M. Slot, Arieke S. B. Kampstra, Sanne Kroos, Rian Schopmeijer, +5 more
1citations