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Comparison of the Effectiveness and Safety of the Oral Selective Inhibitor of Nuclear Export, Selinexor, in Diffuse Large B Cell Lymphoma Subtypes2021 Clinical Lymphoma Myeloma & Leukemia article Medicine Lymphoma Diagnosis and Treatment Open access
Olivier Casasnovas, George Follows, Josée M. Zijlstra, Joost S.P. Vermaat, Nagesh Kalakonda, Sylvain Choquet, +26 more
9citations -
Outcomes of paediatric patients with B-cell acute lymphocytic leukaemia with ABL-class fusion in the pre-tyrosine-kinase inhibitor era: a multicentre, retrospective, cohort study
Monique L. den Boer, Gunnar Cario, Anthony V. Moorman, Judith M. Boer, Hester A. de Groot‐Kruseman, Marta F. Fiocco, +18 more
71citations -
Selinexor in patients with relapsed or refractory diffuse large B-cell lymphoma (SADAL): a single-arm, multinational, multicentre, open-label, phase 2 trial2020 The Lancet Haematology article Medicine Lymphoma Diagnosis and Treatment Open access cited by 2 patents
Nagesh Kalakonda, Marie Maerevoet, Federica Cavallo, George Follows, Andre Henri Goy, Joost S.P. Vermaat, +30 more
345citations -
Selinexor Efficacy and Safety Are Independent of Renal Function in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL): A Post-Hoc Analysis from the Pivotal Phase 2b Sadal Study
Michael W. Schuster, Miguel Ángel Canales, Jason R. Westin, Josée M. Zijlstra, George Follows, Reem Karmali, +32 more
3citations -
MDS-278 Substantial Increases in Paroxysmal Nocturnal Hemoglobinuria (PNH) Red Blood Cell Clone Size With Oral Iptacopan Monotherapy Confirms Control of Hemolysis in Complement Inhibitor-Naive PNH Patients2023 Clinical Lymphoma Myeloma & Leukemia conference-abstract Immunology and Microbiology Complement system in diseases Open access
Régis Peffault de Latour, Bing Han, Jaroslaw Pawel Maciejewski, Yasutaka Ueda, Rong Fu, Li Zhang, +15 more
1citations -
Fatty acid metabolism in aggressive B-cell lymphoma is inhibited by tetraspanin CD372022 Nature Communications article Biochemistry, Genetics and Molecular Biology Cancer, Lipids, and Metabolism Open access
Rens Peeters, Jorge Cuenca‐Escalona, Esther A. Zaal, Anna T. Hoekstra, Anouk C. G. Balvert, Marcos Vidal-Manrique, +10 more
38citations -
Effect of Age on the Efficacy and Safety of Single Agent Oral Selinexor in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL): A Post-Hoc Analysis of the Sadal Pivotal Study
Michael W. Schuster, Miguel Ángel Canales, Jason R. Westin, Josée M. Zijlstra, George Follows, Reem Karmali, +32 more
3citations -
Rationale for and Design of Papilio-1: A Phase 1/2, Multicenter, Open-Label Study to Evaluate the Feasibility, Safety, and Efficacy of Point-of-Care-Manufactured Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor T Cells (GLPG5301) in Relapsed/Refractory Multiple Myeloma
Niels W.C.J. van de Donk, Sébastien Anguille, Jo Caers, Marte C. Liefaard, Christian J. Jacques, Anna D.D. van Muyden
1citations -
Safety, pharmacokinetics (PK), pharmacodynamics (PD) and preliminary efficacy of AZD2936, a bispecific antibody targeting PD-1 and TIGIT, in checkpoint inhibitor (CPI)-experienced advanced/metastatic non-small-cell lung cancer (NSCLC): First report of ARTEMIDE-01.2023 Journal of Clinical Oncology conference-abstract Medicine Cancer Immunotherapy and Biomarkers Open access
Kristoffer Staal Rohrberg, Mariana Brandão, Eduardo Castañón Álvarez, Enriqueta Felip, Eelke Hiddo Gort, T. Jeroen N. Hiltermann, +14 more
22citations -
Serum levels of soluble B and T lymphocyte attenuator predict overall survival in patients undergoing immune checkpoint inhibitor therapy for solid malignancies2021 International Journal of Cancer article Medicine Cancer Immunotherapy and Biomarkers Open access
Joao Gorgulho, Christoph Roderburg, Felix Heymann, Maximilian Franz Schulze-Hagen, Fabian Beier, Mihael Vucur, +6 more
33citations -
P774: SUBSTANTIAL INCREASES IN PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) RED BLOOD CELL CLONE SIZE WITH ORAL IPTACOPAN MONOTHERAPY CONFIRMS CONTROL OF HEMOLYSIS IN COMPLEMENT INHIBITOR-NAÏVE PNH PATIENTS
Régis Peffault de Latour, Bing Han, Jaroslaw Pawel Maciejewski, Yutaka Ueda, Rong Fu, Li Zhang, +15 more
3citations -
Huib32: A Potent and Selective USP32 Inhibitor Modulating Endosomal Processes and Advancing Cell-Permeable USP32 Probes2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Stephan Scherpe, Vito Pol, Raymond Kooij, Adán Pinto-Fernández, Rayman T.N. Tjokrodirijo, Darragh Patrick O'Brien, +6 more
1citations -
Oral Monotherapy with Iptacopan, a Proximal Complement Inhibitor of Factor B, Has Superior Efficacy to Intravenous Terminal Complement Inhibition with Standard of Care Eculizumab or Ravulizumab and Favorable Safety in Patients with Paroxysmal Nocturnal Hemoglobinuria and Residual Anemia: Results from the Randomized, Active-Comparator-Controlled, Open-Label, Multicenter, Phase III Apply-PNH Study
Régis Peffault de Latour, Alexander Roeth, Austin Gladston Kulasekararaj, Phillip Scheinberg, Yasutaka Ueda, Carlos M. de Castro, +15 more
23citations -
Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Antitumor Activity of the Cyclin-Dependent Kinase-9 (CDK9) Inhibitor AZD4573 in Relapsed/Refractory Hematological Malignancies: A Phase 1 First-in-Human Study
Tim H. Brümmendorf, Patrick G. Medd, Raphael Koch, Stephan Stilgenbauer, Shringi Sharma, Yun He, +4 more
8citations -
Peripheral Blood Immune Cell Composition After Autologous MSC Infusion in Kidney Transplantation Recipients2023 Transplant International article Medicine Renal Transplantation Outcomes and Treatments Open access
Sanne H. Hendriks, Sebastiaan Heidt, Axel Ronald Schulz, Johan Willem de Fijter, Marlies E. J. Reinders, Frits Koning, +1 more
9citations