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A proteomic map of B cell activation and its shaping by mTORC1, MYC and iron2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Olivia James, Linda V. Sinclair, Nadejda Lefter, Andrew J.M. Howden
1citations -
Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation2022 Science Advances article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Theresa Kissel, Changrong Ge, Lise Hafkenscheid, Joanneke C. Kwekkeboom, Linda M. Slot, Marco Cavallari, +18 more
77citations -
FcγRIIB regulates autoantibody responses by limiting marginal zone B cell activation2022 Journal of Clinical Investigation article Medicine Systemic Lupus Erythematosus Research Open access
Ashley N. Barlev, Susan Malkiel, Izumi Kurata-Sato, Annemarie L Dorjée, Jolien Suurmond, Betty Diamond
30citations -
Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation2023 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Aldo Spanjaard, Maria Stratigopoulou, Daniël de Groot, Muhammad Assad Aslam, Paul C.M. van den Berk, Chantal Stappenbelt, +7 more
2citations -
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL2024 The Journal of Experimental Medicine article Medicine Lymphoma Diagnosis and Treatment Open access
Janneke A. Eken, Marvyn T. Koning, Kristýna Kupcová, Julieta Sepúlveda-Yáñez, Ruben A. L. de Groen, Edwin Quinten, +10 more
19citations -
Increased Phosphorylation of Intracellular Signaling Molecules Indicates Continuous Activation of Human Autoreactive B‐Cells2025 European Journal of Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Sanne Kroos, Nienke J. Blomberg, Joanneke C. Kwekkeboom, Rudi W. Hendriks, Odilia B. J. Corneth, René E. M. Toes, +1 more
4citations -
Cell-Specific Role of Platelet-Derived Growth Factor Subunit B (PDGF-B) in Kidney Fibrosis2024 Journal of the American Society of Nephrology article Medicine Chronic Kidney Disease and Diabetes
Barbara M. Klinkhammer, Eva Miriam Buhl, Tim Caspers, Dickson W.L. Wong, Michaël Goedertier, David Laurin Hölscher, +2 more
0citations -
Effect of Antigen Valency on Autoreactive B-Cell Targeting2023 Molecular Pharmaceutics article Medicine Rheumatoid Arthritis Research and Therapies Open access
Margot J. van Weijsten, Kevin R. Venrooij, Lianne P. W. M. Lelieveldt, Theresa Kissel, Erik van Buijtenen, Floris J. van Dalen, +3 more
4citations -
DuoBody-CD3xCD20 induces potent T-cell-mediated killing of malignant B cells in preclinical models and provides opportunities for subcutaneous dosing2020 EBioMedicine article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 59 patents
Patrick J. Engelberts, Ida H. Hiemstra, Bart de Jong, Danita H. Schuurhuis, Joyce I. Meesters, Irati Beltrán Hernández, +10 more
181citations -
Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells2024 Science Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Julian Staniek, Geoffroy Andrieux, Melanie Boerries, Iga Janowska, Manuel Fuentes, Paula Díez, +37 more
25citations -
Potential Pathogenic Impact of Cow’s Milk Consumption and Bovine Milk-Derived Exosomal MicroRNAs in Diffuse Large B-Cell Lymphoma2023 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Bodo Clemens Melnik, Rudolf Stadler, Ralf Weiskirchen, Claus Leitzmann, Gerd Schmitz
17citations -
Research-based flow cytometry assays for pathogenic assessment in the human B-cell biology of gene variants revealed in the diagnosis of inborn errors of immunity: a Bruton’s tyrosine kinase case-study2023 Frontiers in Immunology article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access
Lucía del Pino Molina, Yolanda Soto Serrano, Keren Reche Yebra, J. Marty Lobo, B. González Martínez, María Bravo García‐Morato, +3 more
4citations -
Combinatorial multimer staining and spectral flow cytometry facilitate quantification and characterization of polysaccharide-specific B cell immunity2023 Communications Biology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Dennis Hoving, Alexandre H. C. Marques, Wesley Huisman, Beckley A. Nosoh, Alicia C. de Kroon, Oscar R. J. van Hengel, +9 more
3citations