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Cholesterol modulates type I/II TGF-β receptor complexes and alters the balance between Smad and Akt signaling in hepatocytes2024 Communications Biology article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Roohi Chaudhary, Laureen S. Goodman, Sai Wang, Anastasia Asimakopoulos, Ralf Weiskirchen, Steven Dooley, +2 more
12citations -
Chidamide increases the sensitivity of refractory or relapsed acute myeloid leukemia cells to anthracyclines via regulation of the HDAC3 -AKT-P21-CDK2 signaling pathway2020 Journal of Experimental & Clinical Cancer Research article Medicine Acute Myeloid Leukemia Research Open access
Hao Wang, Yu-chen Liu, Cheng-ying Zhu, Fei Yan, Meng-zhen Wang, Xiaosu Chen, +7 more
60citations -
Cholesterol modulates type I-type II TGF-β receptor complexes and alters the balance between Smad and Akt signaling in hepatocytes2023 Research Square preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Roohi Chaudhary, Laureen S. Goodman, Sai Wang, Anastasia Asimakopoulo, Ralf Weiskirchen, Steven Dooley, +2 more
0citations -
Glycogen synthase kinase-3 inhibition and insulin enhance proliferation and inhibit maturation of human iPSC-derived cardiomyocytes via TCF and FOXO signaling2024 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Qianliang Yuan, Devin Verbueken, Rafeeh Dinani, Rosa Kim, Eric Schoger, Chloé D. Morsink, +8 more
7citations -
Leucine Reconstitutes Phagocytosis-Induced Cell Death in E. coli-Infected Neonatal Monocytes—Effects on Energy Metabolism and mTOR Signaling2021 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Cell death mechanisms and regulation Open access
Stephan Dreschers, Kim Ohl, Julia Möllmann, Klaus Tenbrock, Thorsten W Orlikowsky
5citations -
RNF12 is regulated by AKT phosphorylation and promotes TGF-β driven breast cancer metastasis2022 Cell Death and Disease article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Yongsheng Huang, Sijia Liu, Mengjie Shan, Sophie C. Hagenaars, Wilma E. Mesker, Danielle Cohen, +9 more
20citations -
2,8-Dihydroxyadenine-induced nephropathy causes hexosylceramide accumulation with increased mTOR signaling, reduced levels of protective SirT3 expression and impaired renal mitochondrial function2023 Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease article Medicine Chronic Kidney Disease and Diabetes Open access
Julia Moellmann, Katja Krueger, Dickson W.L. Wong, Barbara M. Klinkhammer, Eva Miriam Buhl, Jonas Dehairs, +7 more
19citations -
Increased Phosphorylation of Intracellular Signaling Molecules Indicates Continuous Activation of Human Autoreactive B‐Cells2025 European Journal of Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Sanne Kroos, Nienke J. Blomberg, Joanneke C. Kwekkeboom, Rudi W. Hendriks, Odilia B. J. Corneth, René E. M. Toes, +1 more
4citations -
High concentrations of Porphyromonas gingivalis-LPS downregulate Tlr4 and modulate phosphorylation of ERK and AKT in murine cementoblasts2022 Annals of Anatomy - Anatomischer Anzeiger article Dentistry Oral microbiology and periodontitis research
Corinna Marie Schön, Rogerio Bastos Craveiro, Christian Niederau, Georg Conrads, Holger Jahr, Thomas Pufe, +1 more
6citations -
Impact of age on liver damage, inflammation, and molecular signaling pathways in response to femoral fracture and hemorrhage2023 Frontiers in Immunology article Medicine Trauma, Hemostasis, Coagulopathy, Resuscitation Open access
Fanshuai Meng, Yuzhuo Zhou, Alessa Wagner, Jasmin Maria Bülow, Kernt Köhler, Claudia Neunaber, +2 more
12citations -
Inhibition of murine colorectal cancer metastasis by targeting M2-TAM through STAT3/NF-kB/AKT signaling using macrophage 1-derived extracellular vesicles loaded with oxaliplatin, retinoic acid, and Libidibia ferrea2023 Biomedicine & Pharmacotherapy article Biochemistry, Genetics and Molecular Biology Extracellular vesicles in disease Open access
Thaís Gomes de Carvalho, Pablo Lara, Carla Jorquera‐Cordero, Cícero Flávio Soares Aragão, Artur de Santana Oliveira, Vinícius Barreto Garcia, +5 more
50citations -
Integrative analysis of multi-omics data reveals importance of collagen and the PI3K AKT signalling pathway in CAKUT2024 Scientific Reports article Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Jumamurat R. Bayjanov, Cenna Doornbos, Ozan Özışık, Woosub Shin, Núria Queralt-Rosiñach, Daphne Wijnbergen, +9 more
2citations -
Downregulation of miR‐193a/b‐3p during HPV‐induced cervical carcinogenesis contributes to anchorage‐independent growth through PI3K–AKT pathway regulators2023 Journal of Medical Virology article Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Mengfei Xu, Angelina Huseinovic, Annelieke Jaspers, Lushun Yuan, Renske D.M. Steenbergen
15citations -
Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies2020 Molecular Systems Biology article Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Federica Eduati, Patricia Jaaks, Jessica Wappler, Thorsten Cramer, Christoph A. Merten, Mathew J. Garnett, +1 more
79citations