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IL-6 signaling in macrophages is required for immunotherapy-driven regression of tumors2021 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immune cells in cancer Open access
Elham Beyranvand Nejad, Camilla Labrie, Marit J van Elsas, Jan Willem Kleinovink, Hans‐Willi Mittrücker, Kees L. M. C. Franken, +5 more
47citations -
Impairment of carbonic anhydrase IX ectodomain cleavage reinforces tumorigenic and metastatic phenotype of cancer cells2020 British Journal of Cancer article Biochemistry, Genetics and Molecular Biology Enzyme function and inhibition Open access
Ivana Kajanová, Miriam Zaťovičová, Lenka Jelenska, Olga Sedlakova, Monika Baráthová, Lucia Csáderová, +11 more
22citations -
Nintedanib Targets KIT D816V Neoplastic Cells Derived from Induced Pluripotent Stem cells of Systemic Mastocytosis2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Mast cells and histamine Open access
Marcelo A. S. Toledo, Malrun Gatz, Stephanie Sontag, Karoline Veronika Gleixner, Gregor Eisenwort, Kristina Feldberg, +21 more
4citations -
Lifestyle score is associated with cellular immune profiles in healthy Tanzanian adults2024 Brain Behavior & Immunity - Health article Immunology and Microbiology Immune responses and vaccinations Open access
Jeremia Jackson Pyuza, Marloes M.A.R. van Dorst, Koen A. Stam, Linda J. Wammes, Marion H. König, Vesla I. Kullaya, +11 more
2citations -
Abstract A129: Bispecific antibody Ubamatamab induces personalized anti-tumor immune responses in an ex vivo platform for ovarian cancer2025 Molecular Cancer Therapeutics conference-abstract Medicine Ovarian cancer diagnosis and treatment
Esmee Koedoot, Felix M. Behr, Timothy J. P. Sijsenaar, Léa Le Large, Cor Doede de Kroon, Anne M. van Altena, +6 more
0citations -
Cellular context shapes the transcriptomic impact of somatic variants2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer Genomics and Diagnostics Open access
Peisen Sun, Peng Jia, Chuyuan Lou, Xiaona Li, Miaojing Li, Ruifen Zhang, +23 more
0citations -
Protamine expression in somatic cells condenses chromatin and disrupts transcription without altering DNA methylation2025 Epigenetics & Chromatin article Biochemistry, Genetics and Molecular Biology Genomics and Chromatin Dynamics Open access
Deepika Puri, Alexandra Bott, Monica Varona Baranda, Esra Dursun Torlak, Gina Esther Merges, Hubert Schorle, +1 more
0citations -
Spectrum of histiocytic neoplasms associated with diverse haematological malignancies bearing the same oncogenic mutation2020 The Journal of Pathology Clinical Research article Medicine Histiocytic Disorders and Treatments Open access
Paul Geraeds Kemps, Konnie M. Hebeda, Steven T. Pals, Robert M. Verdijk, King Hong Lam, Annette H. Bruggink, +9 more
56citations -
Mining a human transcriptome database for chemical modulators of NRF22020 PLoS ONE article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
John P. Rooney, Brian N. Chorley, Steven W. Hiemstra, Steven Wink, Xuting Wang, Douglas A. Bell, +2 more
54citations -
Reactivation of BMP signaling by suboptimal concentrations of MEK inhibitor and FK506 reduces organ-specific breast cancer metastasis2020 Cancer Letters article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Jiang Ren, Yanhong Wang, Thomas M. B. Ware, Josephine Iaria, Peter ten Dijke, Hong‐Jian Zhu
41citations -
ST3GAL5‐catalyzed gangliosides inhibit TGF‐β‐induced epithelial‐mesenchymal transition via TβRI degradation2022 The EMBO Journal article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Jing Zhang, Gerard van der Zon, Jin Ma, Hailiang Mei, Birol Cabukusta, Cedrick Agaser, +4 more
39citations -
Pyroptosis-inducing active caspase-1 as a genetic adjuvant in anti-cancer DNA vaccination2022 Vaccine article Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 1 patent
Tsolère Arakelian, Koen Oosterhuis, Elena Tondini, Mandy Los, Jana Vree, Mariska van Geldorp, +7 more
29citations -
A new model of Notch signalling: Control of Notch receptor cis-inhibition via Notch ligand dimers2023 PLoS Computational Biology article Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access cited by 2 patents
Daipeng Chen, Zary Forghany, Xinxin Liu, Haijiang Wang, Roeland M. H. Merks, David A. Baker
20citations -
Cucurbitacin E and I target the JAK/STAT pathway and induce apoptosis in Sézary cells2020 Biochemistry and Biophysics Reports article Medicine Cutaneous lymphoproliferative disorders research Open access
Isabella J. Brouwer, Jacoba J. Out‐Luiting, Maarten H. Vermeer, Cornelis P. Tensen
14citations -
Highly Specific Miniaturized Fluorescent Monoacylglycerol Lipase Probes Enable Translational Research2025 Journal of the American Chemical Society article Medicine Cannabis and Cannabinoid Research Open access
Axel Hentsch, Mónica Guberman, Silke Radetzki, Mirjam C. W. Huizenga, Yingfang He, Jörg Contzen, +18 more
13citations