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Strand-specific single-cell methylomics reveals distinct modes of DNA demethylation dynamics during early mammalian development2021 Nature Communications article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Maya Sen, Dylan Mooijman, Alex Chialastri, Jean-Charles Boisset, Mina Popovic, Björn Heindryckx, +3 more
30citations -
Association Between the Magnitude of Intravenous Busulfan Exposure and Development of Hepatic Veno-Occlusive Disease in Children and Young Adults Undergoing Myeloablative Allogeneic Hematopoietic Cell Transplantation39citations
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Current challenges in cell and gene therapy: a joint view from the European Committee of the International Society for Cell & Gene Therapy (ISCT) and the European Society for Blood and Marrow Transplantation (EBMT)
Fermin M. Sanchez-Guijo, Joaquim Vives, Annalisa Ruggeri, Christian Chabannon, Selim Corbacioglu, Harry Dolstra, +12 more
30citations -
YAP1 Contributes to The Development of Contractile Force and Sarcomere Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Vladimír Vinarský, Stefania Pagliari, Cristina Mazzotti, Katerina Jirakova, Zuzana Garlíková, Enrico Di Iuri, +9 more
1citations -
ECM-transmitted shear stress induces apoptotic cell extrusion in early breast gland development2022 Frontiers in Cell and Developmental Biology article Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Florian Friedland, Srivalliputtur Sarath Babu, Ronald Springer, Yannick Herfs, J. Gehlen, H.-J. Krause, +3 more
9citations -
Preclinical Development of Autologous Hematopoietic Stem Cell-Based Gene Therapy for Immune Deficiencies: A Journey from Mouse Cage to Bed Side2020 Pharmaceutics article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Laura García-Pérez, Anita Ordas, Kirsten Canté-Barrett, Pauline Meij, Karin Pike‐Overzet, Arjan C. Lankester, +1 more
10citations -
Development of a high-throughput in vitro screening method for the assessment of cell-damaging activities of snake venoms2023 PLoS neglected tropical diseases article Biochemistry, Genetics and Molecular Biology Venomous Animal Envenomation and Studies Open access
Mátyás A. Bittenbinder, Liliana Capinha, Daniel Da Costa Pereira, Julien Slagboom, Bas van de Velde, Nicholas R. Casewell, +3 more
11citations -
A scalable tumor-vasculature-on-chip for CAR T cell trafficking and efficacy studies2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Engineering 3D Printing in Biomedical Research Open access
Luuk de Haan, Aleksandra Olczyk, Thomas Olivier, Joris Wesselius, Johnny Suijker, Claudia Al-Mardini, +3 more
1citations -
Quantitative modeling of tumor dynamics and development of drug resistance in non‐small cell lung cancer patients treated with erlotinib2024 CPT Pharmacometrics & Systems Pharmacology article Medicine Lung Cancer Treatments and Mutations Open access
Anyue Yin, G. Veerman, J. G. Coen van Hasselt, Christi M. J. Steendam, Hendrikus Jan Dubbink, Henk‐Jan Guchelaar, +4 more
6citations -
Development and Portability of a Text Mining Algorithm for Capturing Disease Progression in Electronic Health Records of Patients With Stage IV Non–Small Cell Lung Cancer2024 JCO Clinical Cancer Informatics article Computer Science Machine Learning in Healthcare Open access
Marjon V. Verschueren, Hanieh Abedian Kalkhoran, Maarten J. Deenen, Ben E.E.M. van den Borne, J. Zwaveling, Loes E. Visser, +3 more
2citations -
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development2021 Atherosclerosis article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Ana Quiles‐Jiménez, Ida Gregersen, Filip M. Segers, Tonje Skarpengland, Penelope Kroustallaki, Kuan Yang, +24 more
19citations -
Development of DuoMYC: a synthetic cell penetrant miniprotein that efficiently inhibits the oncogenic transcription factor MYC2024 Angewandte Chemie International Edition article Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Brecht D. Ellenbroek, Jan Pascal Kahler, Damiano Arella, Cherina Lin, Willem Jespers, Eliane Ann-Katrin Züger, +2 more
10citations -
Development of DuoMYC: a synthetic cell penetrant miniprotein that efficiently inhibits the oncogenic transcription factor MYC2024 Angewandte Chemie article Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Brecht D. Ellenbroek, Jan Pascal Kahler, Damiano Arella, Cherina Lin, Willem Jespers, Eliane Ann-Katrin Züger, +2 more
0citations -
Development and validation of a supervised deep learning algorithm for automated whole‐slide programmed death‐ligand 1 tumour proportion score assessment in non‐small cell lung cancer
Liesbeth M. Hondelink, Melek Hüyük, Pieter E. Postmus, Vincent T.H.B.M. Smit, Sami Blom, Jan H. von der Thüsen, +1 more
49citations -
Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Alexandra de la Porte, Julia Schröder, Moritz Thomas, Johanna Geuder, Michael Sterr, Leslie E. Sanderson, +5 more
1citations -
Generation of three induced pluripotent stem cell clones from a functional single ventricle patient carrying the BRAF c.1897 T > C variant2025 Stem Cell Research article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Elizaveta Polyakova, Marco C. DeRuiter, Emile Nühn, Monique R.M. Jongbloed
0citations -
Age Distribution of Multiple Functionally Relevant Subsets of CD4+ T Cells in Human Blood Using a Standardized and Validated 14-Color EuroFlow Immune Monitoring Tube2020 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Vitor Botafogo, Martín Pérez‐Andrés, María Jara‐Acevedo, Paloma Bárcena, Georgiana Emilia Grigore, Alejandro Hernández-Delgado, +16 more
60citations -
Single-Cell Roadmap of Early Hemato-Endothelial Development: Functions of Atf3, Zfp711 and Bcl6b2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Hematopoietic Stem Cell Transplantation Open access
Rıdvan Çeti̇n, Giulia Picco, Jente van Staalduinen, Eric M. Bindels, Remco Michiel Hoogenboezem, Gregory van Beek, +7 more
0citations -
Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID2020 Molecular Therapy — Methods & Clinical Development article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 3 patents
Laura García-Pérez, Marja C.J.A. van Eggermond, Lieke van Roon, Sandra A. Vloemans, Martijn Cordes, Axel Schambach, +16 more
58citations -
Endogenous auxin maintains embryonic cell identity and promotes somatic embryo development in Arabidopsis2022 The Plant Journal article Agricultural and Biological Sciences Plant Molecular Biology Research Open access
Cheryl Philipsen, Arezoo Rahimi, Annisa Ratna Nurillah, Kim Boutilier, Remko Offringa
60citations