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Efficacy and safety of olaparib in patients with tumors harboring alterations in homologous recombination repair pathway associated genes: Results from the Drug Rediscovery Protocol.2024 Journal of Clinical Oncology conference-abstract Medicine PARP inhibition in cancer therapy Open access
Ilse A.C. Spiekman, Niven Mehra, Laurien Joanna Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, +10 more
3citations -
Genetic protection from type 1 diabetes resulting from accelerated insulin mRNA decay2025 Cell article Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
René van Tienhoven, Denis O’Meally, Tristan A. Scott, Kevin V. Morris, John C. Williams, John S. Kaddis, +2 more
26citations -
ER stress promotes mitochondrial DNA mediated type-1 interferon response in beta-cells and interleukin-8 driven neutrophil chemotaxis2022 Frontiers in Endocrinology article Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
Joost M. Lambooij, Mette C. Dekkers, Frank Otto, Françoise Carlotti, Bruno Guigas, Arnaud Zaldumbide
19citations -
Generation of Regulatory T Cells Against Islet Neoantigen2026 European Journal of Immunology article Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
Nicoline H. M. den Hollander, Chelsea Gootjes, Maurits G. Staal, Antoinette M. Joosten, Tatjana Nikolić, Bart O. Roep, +1 more
0citations -
Post-transcriptional regulatory mechanisms in human islets inferred from cell type-specific eQTLs detected by single-cell RNA-seq2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Twan J. J. de Winter, Miha Sovrovic, Han Sun, James D. Johnson, Patrick Edward MacDonald, Anna L. Gloyn, +3 more
0citations -
Systematic evaluation of clinically used biomaterials to determine their suitability for fabrication of beta cell delivery devices2021 Journal of Immunology and Regenerative Medicine article Medicine Pancreatic function and diabetes Open access
Adam L. Stell, Sami G. Mohammed, Rick H. W. de Vries, Marten A. Engelse, Eelco J.P. de Koning, Mireille M.J.P.E. Sthijns, +2 more
1citations -
Examination of the Igls Criteria for Defining Functional Outcomes of β-cell Replacement Therapy: IPITA Symposium Report2021 The Journal of Clinical Endocrinology & Metabolism article Medicine Pancreatic function and diabetes Open access
Cyril P. Landstra, Axel Andrès, Mikaël Chetboun, Caterina Conte, Yvonne M. Kelly, Thierry Berney, +7 more
34citations -
miRNA-642a-3p protects β cells from glucolipotoxicity2025 Molecular Therapy — Nucleic Acids article Medicine Pancreatic function and diabetes Open access cited by 1 patent
Sandra S. Pinhanços, Joana Moitinho Oliveira, C. Henrique Alves, Cláudia M. Deus, Twan J. J. de Winter, Sofia Viana, +7 more
3citations