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The PBPK LeiCNS-PK3.0 framework predicts Nirmatrelvir (but not Remdesivir or Molnupiravir) to achieve effective concentrations against SARS-CoV-2 in human brain cells2022 European Journal of Pharmaceutical Sciences article Medicine SARS-CoV-2 and COVID-19 Research Open access
Mohammed A. A. Saleh, Makoto Hirasawa, Ming Sun, Berfin Gülave, Jeroen Elassaiss‐Schaap, Elizabeth C. M. de Lange
10citations -
MicroRNAs modulate SARS ‐ CoV ‐2 infection of primary human hepatocytes by regulating the entry factors ACE2 and TMPRSS22024 Liver International article Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Rajendra Khanal, Natalie Heinen, Alexandra Bogomolova, Toni Luise Meister, Simon T. Herrmann, Saskia Westhoven, +11 more
4citations -
Probing nano-QSAR to assess the interactions between carbon nanoparticles and a SARS-CoV-2 RNA fragment2021 Ecotoxicology and Environmental Safety article Engineering Graphene and Nanomaterials Applications Open access
Fan Zhang, Zhuang Wang, Martina G. Vijver, Willie J.G.M. Peijnenburg
25citations -
Voclosporin and the Antiviral Effect Against SARS-CoV-2 in Immunocompromised Kidney Patients2023 Kidney International Reports article Medicine COVID-19 Clinical Research Studies Open access cited by 1 patent
Eline J. Arends, Soufian Meziyerh, Dirk Jan A. R. Moes, Sylvia W.A. Kamerling, Sandra van der Kooy, Natacha S. Ogando, +9 more
1citations -
Compounds derived from Humulus lupulus inhibit SARS-CoV-2 papain-like protease and virus replication2023 Phytomedicine article Pharmacology, Toxicology and Pharmaceutics Hops Chemistry and Applications Open access
Anna-Maria Herzog, Katharina Göbel, Luigi Marongiu, Natalia Ruétalo, Marta Campos Alonso, Christian Leischner, +8 more
14citations -
Abstract S05-01: Profound CD8 T-cell responses towards SARS-CoV-2 OFR1ab in COVID-19 patients2020 Clinical Cancer Research conference-abstract Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches
Anastasia Gangaev, Steven L. C. Ketelaars, Sanne Patiwael, Anna Dopler, Olga I. Isaeva, Kelly Hoefakker, +13 more
1citations -
A blueprint for high affinity SARS-CoV-2 Mpro inhibitors from activity-based compound library screening guided by analysis of protein dynamics2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access
Jonas Goßen, Simone Albani, Anton Hanke, Benjamin Philipp Joseph, Cathrine C. Bergh, Maria Kuzikov, +14 more
5citations -
Antiviral Effects of Voclosporin on SARS-CoV-2 in Immunocompromised Kidney Patients2022 Journal of the American Society of Nephrology article Medicine COVID-19 Clinical Research Studies
Eline J. Arends, Soufian Meziyerh, Dirk Jan A. R. Moes, Sylvia W.A. Kamerling, Sandra W. van der Kooij, Natacha S. Ogando, +8 more
1citations -
OC 05.1 Impact of Low Molecular Weight Heparin (LMWH) on SARS-CoV2 Infection: HEPARIN-SARS-CoV2 Clinical Trial2023 Research and Practice in Thrombosis and Haemostasis article Medicine COVID-19 Clinical Research Studies Open access
Remedios Otero, Demetrio González-Vergara, Isabel Socorro Caparrós-Miranda, E. Mendoza-Zambrano, Alberto García‐Ortega, Consolación Rodríguez‐Matute, +3 more
0citations -
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids2021 Cell stem cell article Medicine COVID-19 Clinical Research Studies Open access cited by 1 patent
Jitske Jansen, Katharina C. Reimer, James Shiniti Nagai, Finny S. Varghese, Gijs J. Overheul, Marit A. de Beer, +90 more
257citations -
Health Outcomes and Cost-effectiveness of Monoclonal SARS-CoV-2 Antibodies as Pre-exposure Prophylaxis2023 JAMA Network Open article Economics, Econometrics and Finance Health Systems, Economic Evaluations, Quality of Life Open access
Stephanie Popping, Brooke E Nichols, Brent Appelman, Jason J. Biemond, Magda Vergouwe, Frits Richard Rosendaal, +30 more
14citations -
Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design2021 Nature Reviews Molecular Cell Biology review Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 2 patents
Brandon F. Malone, Nadya Urakova, Eric J. Snijder, Elizabeth A. Campbell
538citations -
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages2021 Science Translational Medicine article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 2 patents
Willianne Hoepel, Hung‐Jen Chen, Chiara Elisabeth Geyer, Sona Allahverdiyeva, Xue Daphne Manz, Steven W. de Taeye, +30 more
283citations -
Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity2021 Nature Communications article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 12 patents
Cyrielle E. Fougeroux, Louise Goksøyr, Manja Idorn, Vladislav Soroka, Sebenzile K. Myeni, Robert Dagil, +41 more
132citations -
mRNA vaccines against SARS-CoV-2 induce comparably low long-term IgG Fc galactosylation and sialylation levels but increasing long-term IgG4 responses compared to an adenovirus-based vaccine
Jana Sophia Buhre, Tamás Pongrácz, Inga Künsting, Anne Sophie Lixenfeld, Wenjun Wang, Jan Nouta, +14 more
91citations -
SARS-CoV-2-neutralising monoclonal antibodies for treatment of COVID-192021 Cochrane Database of Systematic Reviews article Medicine SARS-CoV-2 and COVID-19 Research cited by 11 patents
Nina Kreuzberger, Caroline Hirsch, Khai Li Chai, Vanessa Piechotta, Sarah J Valk, Lise J Estcourt, +8 more
66citations -
Potent Inhibition of SARS-CoV-2 nsp14 N 7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues2022 Journal of Medicinal Chemistry article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 1 patent
Rostom Ahmed‐Belkacem, Marcel Hausdorff, Adrien Delpal, Priscila Sutto‐Ortiz, Agathe M. G. Colmant, Franck Touret, +7 more
60citations