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A randomized embedded multifactorial adaptive platform for extra corporeal membrane oxygenation (REMAP ECMO) – design and rationale of the left ventricular unloading trial domain
Myrthe P. J. van Steenwijk, Joost van Rosmalen, Carlos V. Elzo Kraemer, Dirk Wilhelm Donker, Jeannine A. J. M. Hermens, Adriaan O. Kraaijeveld, +20 more
5citations -
A randomized controlled trial comparing conservative versus surgical treatment in patients with foot drop due to peroneal nerve entrapment: results of an internal feasibility pilot study
Christophe Oosterbos, Sofie Rummens, Kris Bogaerts, Anaïs Van Hoylandt, Sophie Hoornaert, Frank J. M. Weyns, +6 more
3citations -
Personalized Decision Making on Genomic Testing in Early Breast Cancer: Expanding the MINDACT Trial with Decision-Analytic Modeling2021 Medical Decision Making article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Ewout Willem Steyerberg, Liesbeth C. de Wreede, David V. Klaveren, Patrick M. Bossuyt
4citations -
Impact of changing open-label drug prescription policies on consent rates in a neonatal trial: a quasinatural experiment2026 Archives of Disease in Childhood Fetal & Neonatal article Medicine Ethics in Clinical Research Open access
Kelly K. Storm, Robert B. Flint, Wes Onland, Sylvia A Obermann-Borst, Jarinda A. Poppe, Debbie H. G. M. Nuytemans, +23 more
0citations -
Fosfomycin Vs Ciprofloxacin as Oral Step-Down Treatment for Escherichia coli Febrile Urinary Tract Infections in Women: A Randomized, Placebo-Controlled, Double-Blind, Multicenter Trial
Sander Kuiper, Cees van Nieuwkoop, Robert Jan Hassing, Suzan P. van Mens, Akke K. van der Bij, Suzanne E. Geerlings, +18 more
24citations -
Regurgitant volume to LA volume ratio in patients with secondary MR: the COAPT trial2023 European Heart Journal - Cardiovascular Imaging article Medicine Cardiac Valve Diseases and Treatments Open access
Augustin Coisne, Andrea Scotti, Juan F. Granada, Paul Arthur Grayburn, Michael J. Mack, David J. Cohen, +9 more
6citations -
Ten-Year Outcome of Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer: The Randomized Controlled CROSS Trial2021 Journal of Clinical Oncology article Medicine Esophageal Cancer Research and Treatment Open access
Ben M. Eyck, J. Jan B. van Lanschot, Maarten C.C.M. Hulshof, Berend J. van der Wilk, Joël Shapiro, Pieter van Hagen, +24 more
822citations -
Efficacy, Safety, and Quality of Life of Pegcetacoplan in Japanese Patients with Paroxysmal Nocturnal Hemoglobinuria Treated within the Phase 3 PEGASUS Trial2024 Acta Haematologica article Immunology and Microbiology Complement system in diseases Open access
Hisakazu Nishimori, Hideyuki Nakazawa, Shinobu Tamura, Toshiki Uchida, Kensuke Usuki, Johan Szamosi, +3 more
4citations -
Radiotherapy or Surgery of the Axilla After a Positive Sentinel Node in Breast Cancer: 10-Year Results of the Randomized Controlled EORTC 10981-22023 AMAROS Trial2022 Journal of Clinical Oncology article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Sanne A. L. Bartels, Mila Donker, Coralie Poncet, Nicolas Sauvé, Marieke Evelien Straver, Cornelis J.�H. van de Velde, +20 more
392citations -
Does paracetamol improve quality of life, discomfort, pain and neuropsychiatric symptoms in persons with advanced dementia living in long-term care facilities? A randomised double-blind placebo-controlled crossover (Q-PID) trial
Paulien H. van Dam, Wilco P. Achterberg, Bettina Sandgathe Husebo, Monique A. A. Caljouw
10citations -
Pulmonary Vein Systolic Flow Reversal and Outcomes in Patients From the Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (COAPT) Trial
Chandrashekar Bohra, Federico M. Asch, Stamatios Lerakis, Stephen Henry Little, Björn Redfors, Zhipeng Zhou, +10 more
2citations -
#1920 Effects of sparsentan after maximized angiotensin receptor blocker (ARB) treatment in patients with IgA nephropathy (IgAN) in the PROTECT trial2025 Nephrology Dialysis Transplantation article Medicine Renal Diseases and Glomerulopathies Open access
Jürgen Floege, Dana V. Rizk, Priscila Preciado, Brad H. Rovin, Rob Geletka, Alex Mercer, +3 more
0citations -
Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial2020 New England Journal of Medicine article Medicine Lung Cancer Diagnosis and Treatment Open access cited by 7 patents
Harry J. de Koning, Carlijn M. van der Aalst, Pim A. de Jong, Ernst T. Scholten, Kristiaan Nackaerts, Marjolein A. Heuvelmans, +18 more
3,687citations -
Primary cutaneous lymphoma: recommendations for clinical trial design and staging update from the ISCL, USCLC, and EORTC2021 Blood article Medicine Cutaneous lymphoproliferative disorders research Open access cited by 1 patent
Elise A. Olsen, Sean J Whittaker, Rein Willemze, Lauren C. Pinter‐Brown, Francine M. Foss, Larisa J. Geskin, +28 more
184citations -
Low dose, add-on prednisolone in patients with rheumatoid arthritis aged 65+: the pragmatic randomised, double-blind placebo-controlled GLORIA trial2022 Annals of the Rheumatic Diseases article Medicine Rheumatoid Arthritis Research and Therapies Open access
Maarten Boers, Linda M. Hartman, Daniela Opriș-Belinski, Reinhard Bos, Marc R. Kok, José António Pereira da Silva, +14 more
166citations -
QR‐421a RNA therapy in retinitis pigmentosa due to mutations in USH2A: Stellar trial Phase[AP1] 1b/2 interim results2022 Acta Ophthalmologica article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders
Isabelle S. Audo, David G. Birch, Thiran Jayasundera, Isabelle Meunier, Rachel M. Huckfeldt, Robert K. Koenekoop, +6 more
12citations -
The potential benefit of statin prescription based on prediction of treatment responsiveness in older individuals: an application to the PROSPER randomized controlled trial2023 European Journal of Preventive Cardiology article Medicine Lipoproteins and Cardiovascular Health Open access
Tri‐Long Nguyen, Stella Trompet, John Brodersen, Jeroen Hoogland, Thomas P. A. Debray, Naveed A. Sattar, +2 more
4citations -
Integration of proteomic aging clocks in a phase 2a clinical trial supports simultaneous geroprotective assessment2026 Nature Biotechnology article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Alex A. Zhavoronkov, Fedor Galkin, Shan Chen, Feng Ren, Alex Aliper, Mikhail O. Durymanov, +13 more
4citations