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Chronic progressive demyelination induces a microglial state with lysosomal dysfunction2026 Nature Neuroscience article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access
Stefan A. Berghoff, Lena Spieth, Simona Vitale, Lennart Schlaphoff, Martin Zirngibl, Niklas Junker, +26 more
0citations -
PHGDH heterogeneity potentiates cancer cell dissemination and metastasis2022 Nature article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Matteo Rossi, Patricia Altea‐Manzano, Margherita Demicco, Ginevra Doglioni, Laura Bornes, Marina Fukano, +45 more
223citations -
Disentangling the genetic basis of rhizosphere microbiome assembly in tomato2022 Nature Communications article Agricultural and Biological Sciences Plant-Microbe Interactions and Immunity Open access
Ben O. Oyserman, Stalin Sarango Flores, Thom Griffioen, Xinya Pan, Elmar van der Wijk, Lotte J. U. Pronk, +12 more
165citations -
ACSL4-dependent ferroptosis does not represent a tumor-suppressive mechanism but ACSL4 rather promotes liver cancer progression2022 Cell Death and Disease article Medicine Ferroptosis and cancer prognosis Open access cited by 1 patent
Julia Grube, Marius Maximilian Woitok, Antje Mohs, Stephanie Erschfeld, Celina Lynen, Christian Trautwein, +1 more
98citations -
Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042)2021 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Phosphodiesterase function and regulation Open access cited by 3 patents
Michael G. Hahn, Thomas F. J. Lampe, Sherif El Sheikh, Nils Griebenow, Elisabeth Woltering, Karl‐Heinz Schlemmer, +20 more
67citations -
Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy2021 Scientific Reports article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Esmee Koedoot, Liesanne Wolters, Marcel Smid, Peter Stoilov, Gerhard A. Burger, Bram Herpers, +5 more
60citations -
Lesch-Nyhan disease causes impaired energy metabolism and reduced developmental potential in midbrain dopaminergic cells2021 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Biochemical and Molecular Research Open access
Vincent McCarty, Huashan Peng, Malvin Jefri, Nuwan C. Hettige, Lilit Antonyan, Liam Crapper, +17 more
49citations -
MiMIR: R-shiny application to infer risk factors and endpoints from Nightingale Health’s 1H-NMR metabolomics data2022 Bioinformatics article Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Daniele Bizzarri, Marcel J. T. Reinders, Marian Beekman, P. Eline Slagboom, Erik B. van den Akker
17citations -
Spatio-temporal transcriptomic analysis reveals distinct nephrotoxicity, DNA damage, and regeneration response after cisplatin2025 Cell Biology and Toxicology article Medicine Chemotherapy-induced organ toxicity mitigation Open access cited by 1 patent
Lukas S. Wijaya, Steven J. Kunnen, Panuwat Trairatphisan, Ciaran P. Fisher, Meredith E. Crosby, Kai Schaefer, +11 more
12citations -
FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver Disease Diagnosis and Treatment Open access
Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M. Lambooij, Hendrik J.P. van der Zande, Enchen Zhou, +12 more
8citations -
Disentangling the genetic basis of rhizosphere microbiome assembly in tomato2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Agricultural and Biological Sciences Plant-Microbe Interactions and Immunity Open access
Ben O. Oyserman, Stalin Sarango Flores, Thom Griffioen, Xinya Pan, Elmar van der Wijk, Lotte J. U. Pronk, +10 more
7citations -
Carriage of rare APOB variants predisposes to severe steatotic liver disease and hepatocellular carcinoma2026 Journal of Clinical Investigation review Medicine Liver Disease Diagnosis and Treatment Open access
Matteo Mureddu, Serena Pelusi, Oveis Jamialahmadi, Marijana Vujković, Lorenzo Miano, Hadi Eidgah Torghabehei, +29 more
5citations -
ERS International Congress, Madrid, 2019: highlights from the Basic and Translational Science Assembly2020 ERJ Open Research article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Niki D. J. Ubags, Jonathan R. Baker, Agnes Wilhelmina Boots, Rita Costa, Natalia El-Merhie, Aurélie Fabre, +7 more
4citations -
Personalisation of the Dutch combined lifestyle intervention SLIMMER improves participant retention and weight loss in people at risk for cardiometabolic disease2025 Scientific Reports article Medicine Diabetes, Cardiovascular Risks, and Lipoproteins Open access
Johanneke E. Oosterman, Dagmar Josine Smid, Regina J. M. Kamstra, Iris M. de Hoogh, Arjan Huizing, Martien P. M. Caspers, +6 more
3citations