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In uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations
Francesca Piaggio, Michela Croce, Francesco Reggiani, Paola Monti, Cinzia Bernardi, Marianna Ambrosio, +16 more
29citations -
Potential allergenicity of Medicago sativa investigated by a combined IgE ‐binding inhibition, proteomics and in silico approach2020 Journal of the Science of Food and Agriculture article Medicine Food Allergy and Anaphylaxis Research
Marwa Yakhlef, Ivana Giangrieco, Maria Antonietta Ciardiello, Immacolata Fiume, Adriano Mari, Lynda Souiki, +1 more
19citations -
A universal cannabinoid CB1 and CB2 receptor TR-FRET kinetic ligand binding assay2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cannabis and Cannabinoid Research Open access
Leire Borrega Roman, Bradley L. Hoare, Miroslav Kosar, Roman C. Sarott, Kacper J. Patej, Jara Bouma, +15 more
0citations -
Fi-score: a novel approach to characterise protein topology and aid in drug discovery studies2020 Journal of Biomolecular Structure and Dynamics article Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics
Austė Kanapeckaitė, Claudia Beaurivage, MATTHEW J. HANCOCK, Erik Verschueren
3citations -
Hybrid MM/CG Webserver: Automatic Set Up of Molecular Mechanics/Coarse-Grained Simulations for Human G Protein-Coupled Receptor/Ligand Complexes2020 Frontiers in Molecular Biosciences article Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access
Jakob Schneider, Rui Pedro Ribeiro, Mercedes Alfonso‐Prieto, Paolo Carloni, Alejandro Giorgetti
9citations -
Cryo-EM structures reveal how ATP and DNA binding in MutS coordinate the sequential steps of DNA mismatch repair2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Alessandro Borsellini, Vladislav Kunetsky, Peter Friedhoff, Meindert Hugo Lamers
1citations -
Fi-score: a novel approach to characterise protein topology and aid in drug discovery studies2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access
Austė Kanapeckaitė, Claudia Beaurivage, MATTHEW J. HANCOCK, Erik Verschueren
2citations -
DNA polymerase actively and sequentially displaces single-stranded DNA-binding proteins2025 Nature Communications article Physics and Astronomy Force Microscopy Techniques and Applications Open access
Longfu Xu, Shikai Jin, Mia Urem, Seung‐Joo Lee, Meindert Hugo Lamers, Xun Chen, +2 more
3citations -
Temperature-Dependent Enzyme-Ligand Recognition Emerges from the Coupling of Protein Dynamics and Hydration2026 ACS Omega article Biochemistry, Genetics and Molecular Biology Enzyme function and inhibition Open access
Binny A. Rudani, Mona Sarter, Tilo Seydel, Simone Wiegand, Andreas Maximilian Stadler
0citations -
Navigating the complexities of docking tools with nicotinic receptors and acetylcholine binding proteins in the realm of neonicotinoids2024 Ecotoxicology and Environmental Safety article Computer Science Computational Drug Discovery Methods Open access
Zakaria Bouchouireb, Damien Olivier‐Jimenez, Titouan Jaunet‐Lahary, Steeve Hervé Thany, Jean‐Yves Le Questel
14citations -
The effect of cancer-associated mutations on ligand binding and receptor function – A case for the 5-HT2C receptor2024 European Journal of Pharmacology article Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access
Chen‐Lin Feng, Rongfang Liu, Xuesong Wang, Willem Jespers, Marina Gorostiola González, Gerard J. P. van Westen, +2 more
1citations -
Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity2021 Nature Communications article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 12 patents
Cyrielle E. Fougeroux, Louise Goksøyr, Manja Idorn, Vladislav Soroka, Sebenzile K. Myeni, Robert Dagil, +41 more
132citations -
Evolution of an interaction between disordered proteins resulted in increased heterogeneity of the binding transition state2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Elin Karlsson, Cristina Paissoni, Amanda M. Erkelens, Zeinab Amiri‐Tehranizadeh, Frieda A. Sorgenfrei, Eva Andersson, +3 more
0citations -
Genetically-encoded probes to determine nonspecific hydrophobic and electrostatic binding in cells2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Advanced Fluorescence Microscopy Techniques Open access
Weiyan Zuo, Meng‐Ruo Huang, Fabian Schmitz, Arnold J. Boersma
2citations -
Molecular basis of ligand binding and receptor activation at the human A3 adenosine receptor2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling Open access
Liudi Zhang, Jesse I. Mobbs, Felix M. Bennetts, Hariprasad Venugopal, Anh T. N. Nguyen, Arthur Christopoulos, +5 more
1citations -
Material-specific binding peptides empower sustainable innovations in plant health, biocatalysis, medicine and microplastic quantification2024 Chemical Society Reviews review Biochemistry, Genetics and Molecular Biology Biochemical and Structural Characterization Open access
Maochao Mao, Leon Ahrens, Julian Luka, Francisca Contreras, Tetiana Kurkina, Marian Bienstein, +8 more
49citations -
High-throughput competitive binding assay for targeting RNA with small molecules: discovery of new PreQ 1 riboswitch ligands2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access
Sophie E.L. Wintermans, Jana S Hoffmann, Mariska D. Tacoma, Indy Broekhuizen, Bjorn R. van Doodewaerd, Paul P. Geurink, +3 more
1citations -
High-throughput competitive binding assay for targeting RNA tertiary structures with small molecules: application to pseudoknots and G-quadruplexes2025 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access
Sophie E.L. Wintermans, Jana S Hoffmann, Victor van Kuijk, Yelda Durmus, Mariska D. Tacoma, Indy Broekhuizen, +6 more
1citations -
Scaling eukaryotic cell‐free protein synthesis achieved with the versatile and high‐yielding tobacco BY‐2 cell lysate2023 Biotechnology and Bioengineering article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access cited by 1 patent
Mainak Das Gupta, Yannick Flaskamp, Robin Roentgen, Hannes Juergens, Jorge Armero‐Gimenez, Frank Albrecht, +9 more
42citations