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Development of a Bioreactor-Coupled Flow-Cell Setup for 3D In Situ Nanotomography of Mg Alloy Biodegradation2023 ACS Applied Materials & Interfaces article Materials Science Magnesium Alloys: Properties and Applications Open access
Jan Reimers, Huu Chánh Trinh, Björn Wiese, Sebastian Meyer, Jens Brehling, Silja Flenner, +10 more
10citations -
Single-cell transcriptomics in bone marrow delineates CD56dimGranzymeK+ subset as intermediate stage in NK cell differentiation2022 Frontiers in Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Janine E. Melsen, Monique M. van Ostaijen-ten Dam, Dorenda J. A. Schoorl, Pieter J. Schol, Daphne A. L. van den Homberg, Arjan C. Lankester, +2 more
17citations -
Ex vivo-generated lymphoid progenitors encompass both T cell and innate lymphoid cell fates2025 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Pierre Gaudeaux, Juliette Paillet, Monah Abou Alezz, Ranjita Devi Moirangthem, Sara Cascione, Marta Martin Corredera, +17 more
0citations -
Reconstitution of the cellular niche requirements for primordial germ cell-like cell progression in humans2026 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Yolanda W. Chang, Marjolein Trimp, Talia van der Helm, Ioannis Moustakas, Albert Blanch-Asensio, Arend W. Overeem, +1 more
5citations -
Light chain skewing in autoantibodies and B-cell receptors of the citrullinated antigen-binding B-cell response in rheumatoid arthritis2021 PLoS ONE article Medicine Rheumatoid Arthritis Research and Therapies Open access cited by 1 patent
Linda M. Slot, Rochelle D. Vergroesen, Priscilla F. Kerkman, Ellen Magadalena Staudinger, Sanne Reijm, Hugo J. van Dooren, +4 more
9citations -
Current challenges in cell and gene therapy: a joint view from the European Committee of the International Society for Cell & Gene Therapy (ISCT) and the European Society for Blood and Marrow Transplantation (EBMT)
Fermin M. Sanchez-Guijo, Joaquim Vives, Annalisa Ruggeri, Christian Chabannon, Selim Corbacioglu, Harry Dolstra, +12 more
30citations -
Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing2021 npj Regenerative Medicine article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Anika Schumacher, Maarten B. Rookmaaker, Jaap A. Joles, Rafael Kramann, Tri Quang Nguyen, Martijn van Griensven, +1 more
60citations -
Reconstitution of human fetal ovaries reveals niche requirements for primordial germ cell-like cell progression2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Yolanda W. Chang, Marjolein Trimp, Talia van der Helm, Albert Blanch-Asensio, Arend W. Overeem, Susana M. Chuva de Sousa Lopes
2citations -
ABO: A 3D stroma-supported culture platform enabling full human B-lymphopoiesis for disease modeling and gene therapy development2026 Cell Reports Medicine article Immunology and Microbiology T-cell and B-cell Immunology Open access
Merijn Braams, Martijn Cordes, Sandra A. Vloemans, Bas de Mooij, Sandra de Bruin-Versteeg, Ashley Wachtmeester, +5 more
0citations -
Faculty Opinions recommendation of Single-cell transcriptomics uncovers an instructive T-cell receptor role in adult γδ T-cell lineage commitment.0citations
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Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID2020 Molecular Therapy — Methods & Clinical Development article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 3 patents
Laura García-Pérez, Marja C.J.A. van Eggermond, Lieke van Roon, Sandra A. Vloemans, Martijn Cordes, Axel Schambach, +16 more
58citations -
Comparative analysis of mouse and human preimplantation development following POU5F1 CRISPR/Cas9 targeting reveals interspecies differences2021 Human Reproduction article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Panagiotis Stamatiadis, Annekatrien Boel, Gwenny Cosemans, Mina Popovic, Bieke Bekaert, Ramesh Reddy Guggilla, +8 more
21citations -
Single-cell RNA sequencing analysis of the human fetal epicardium reveals several new genes involved in regulation of epicardial activation2024 Cardiovascular Research article Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Anke M. Smits, T J Streef, Els Groeneveld, Tessa van Herwaarden, Marie‐José Goumans
0citations -
RFX3 is essential for the development and maturation of human pancreatic islets derived from pluripotent stem cells2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Pancreatic function and diabetes Open access
Bushra Memon, Noura Aldous, Ahmed K. Elsayed, Sadaf Ijaz, Sikander Hayat, Essam Mohamed Abdelalim
0citations -
Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4)2022 Human Molecular Genetics article Biochemistry, Genetics and Molecular Biology Genomics and Chromatin Dynamics Open access
Malvin Jefri, Xin Zhang, Patrick S. Stumpf, Li Zhang, Huashan Peng, Nuwan C. Hettige, +12 more
12citations -
The Hippo pathway component Wwc2 is a key regulator of embryonic development and angiogenesis in mice2021 Cell Death and Disease article Biochemistry, Genetics and Molecular Biology Hippo pathway signaling and YAP/TAZ Open access
Anke Hermann, Guangming Wu, Pavel I. Nedvetsky, Viktoria Constanze Brücher, Charlotte Egbring, Jakob Bonse, +8 more
35citations -
The Changing Face of Oncology Research, Drug Development, and Clinical Practice: Toward Patient‐Focused Precision Therapeutics2020 Clinical Pharmacology & Therapeutics article Mathematics Statistical Methods in Clinical Trials Open access
Karthik Venkatakrishnan, Piet H. van der Graaf, Sarah A. Holstein
4citations