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Interventional gene targeting of the cell cycle regulator Cyclin E1 during hepatocarcinogenesis attenuates cancer progression with limited proliferation, stemness traits and micro-metastasis2020 Zeitschrift für Gastroenterologie conference-paper Medicine Hepatocellular Carcinoma Treatment and Prognosis
Marlene Sophia Kohlhepp, Antje Mohs, Christian Penners, Daniela Lambertz, Frank Tacke, Christian Trautwein, +1 more
0citations -
Generation of human induced pluripotent stem cell line LUMCi027-A and its isogenic gene-corrected line from a patient affected by arrhythmogenic cardiomyopathy and carrying the c.2013delC PKP2 mutation2020 Zenodo (CERN European Organization for Nuclear Research) dataset Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Viviana Meraviglia, Christiaan H. Arendzen, Merve Tok, Angela Serena Maione, Elena Sommariva, Milena Bellin
0citations -
Generation of patient-derived and gene-corrected hiPSC lines from Hereditary Hemorrhagic Telangiectasia type 2 patients with ACVRL1 c.1042delG mutation
Kendy Eduardo Urdaneta, Francijna E. van den Hil, Marga J. Bouma, Herak Manjikian, Christine L. Mummery, Christian M.A.H. Freund, +2 more
0citations -
Generation of human induced pluripotent stem cell line LUMCi027-A and its isogenic gene-corrected line from a patient affected by arrhythmogenic cardiomyopathy and carrying the c.2013delC PKP2 mutation2020 Zenodo (CERN European Organization for Nuclear Research) dataset Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Viviana Meraviglia, Christiaan H. Arendzen, Merve Tok, Angela Serena Maione, Elena Sommariva, Milena Bellin
0citations -
OA10 Systematic review and independent validation of genetic factors of radiographic outcome in rheumatoid arthritis identifies a genome-wide association with CARD92025 Lara D. Veeken conference-abstract Medicine Rheumatoid Arthritis Research and Therapies Open access
Seema Sharma, Ryan Malcolm Hum, Nisha Nair, Lysette Marshall, John Bowes, Alex J. MacGregor, +6 more
0citations -
Transcriptome analysis of conditionally immortalized atrial myocytes: identification of a novel atrium-enriched protein involved in sarcomere assembly and maintenance2021 European Heart Journal article Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Pim R.R. van Gorp, Juan Zhang, J Liu, Roula Tsonaka, Hailiang Mei, S O Dekker, +6 more
0citations -
High-Resolution Spatial Profiling Unveils Cellular Heterogeneity in Murine Atherosclerosis2025 Thrombosis and Haemostasis article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Jan M. Wrobel, Paul Kießling, Emilia Scheidereit, Christoph Kuppe, Venetia Bazioti, Dorothee Atzler, +1 more
2citations -
Selection on Phalanx Development in the Evolution of the Bird Wing2021 Molecular Biology and Evolution article Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access
M. Bakker, Wessel van der Vos, Kaylah de Jager, Wing Yu Chung, Donald A. Fowler, Esther Dondorp, +10 more
11citations -
Plasma cells are not restricted to the CD27+ phenotype: characterization of CD27-CD43+ antibody-secreting cells2023 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Kris Covens, Bert Verbinnen, Britt G. de Jong, Leen Moens, Greet Wuyts, Geert R. Verheyen, +11 more
4citations -
Tissue‐specific methylomic responses to a lifestyle intervention in older adults associate with metabolic and physiological health improvements2024 Aging Cell article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Lucy Sinke, Marian Beekman, Yotam Raz, Thies Gehrmann, Ioannis Moustakas, Alexis Boulinguiez, +11 more
3citations -
WWP2 confers risk to osteoarthritis by affecting cartilage matrix deposition via hypoxia associated genes2022 Osteoarthritis and Cartilage article Medicine Osteoarthritis Treatment and Mechanisms Open access
Margo Tuerlings, George M. C. Janssen, Marcella van Hoolwerff, Alejandro Rodríguez Ruiz, Evelyn Houtman, H. Eka D. Suchiman, +6 more
17citations -
WWP2 osteoarthritis risk allele rs1052429-A confers risk by affecting cartilage matrix deposition via hypoxia associated genes2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Osteoarthritis Treatment and Mechanisms Open access
Margo Tuerlings, George M. C. Janssen, Ilja Boone, Marcella van Hoolwerff, Alejandro Rodríguez Ruiz, Evelyn Houtman, +7 more
1citations -
O-300 Characterization of the transcriptional changes of human endometrium across the window of implantation during natural cycles reveals consistent dynamics2025 Human Reproduction conference-abstract Immunology and Microbiology Reproductive System and Pregnancy Open access
Irene Miguel-Escalada, Berta Gayete-Mor, Lucía Álvarez-González, Marta Trullenque, Anna Blázquez, J J Guillén-Quílez, +7 more
0citations -
Analysis of cancer-associated glycosyltransferases reveals novel targets of non-small cell lung cancer pathogenesis2025 Frontiers in Oncology article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Chang Liu, Thomas van Ee, Jurriaan Janssen, Ernesto Rodríguez, Yongsoo Kim, Teodora Radonic, +4 more
4citations -
Evaluating the Role of AMB-05X in Modulating Key Fibrotic Markers in Human Precision-cut Lung Slices2025 American Journal of Respiratory and Critical Care Medicine conference-abstract Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Christina Hesse, Valerie Beneke, Lena Willmer, Jan Fiedler, Danny David Jonigk, Patrick Zardo, +1 more
0citations