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Lower Dose‐Normalized Tacrolimus Exposure in CYP3A5 *6 vs. *3 Loss‐of‐Function Allele Carriers: A Longitudinal Retrospective Real‐World Study in Kidney Transplant Recipients2025 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Amar D. Levens, Dirk Jan A. R. Moes, Yanick Boer, Aiko P. J. de Vries, Dorottya K. de Vries, Danny van der Helm, +5 more
5citations -
A Phase I, Randomized, Multi‐Dose Study to Evaluate the Enteric Selectivity and Safety of JAK Inhibitor, Lorpucitinib, in Healthy Participants2023 Clinical Pharmacology & Therapeutics article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Xuewen Ma, Gary V. Borzillo, M. Kothe, Madhu Sanga, Gerald Chu, James Greger, +2 more
1citations -
Treating socket discharge and discomfort: a crossover randomised trial of vitamin A ointment, low-dose steroid eyedrops and artificial tears2026 British Journal of Ophthalmology article Biochemistry, Genetics and Molecular Biology Ocular Disorders and Treatments Open access
Arthur Yu Xiang Liu, Stijn W. van der Meeren, Adriaan D. Coumou, Rachel Kalmann, Dyonne T. Hartong
0citations -
Long-Term Outcomes of Increased Versus Conventional Adalimumab Dose Interval for Patients With Crohn’s Disease in Stable Remission: 3-Year Follow-Up of the Randomized Controlled LADI Trial2025 Gastroenterology article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Lisa M.A. van Lierop, C. Janneke van der Woude, Frank Hoentjen, Annemarie Charlotte de Vries, Alexander G L Bodelier, Maurice W. M. D. Lutgens, +5 more
0citations -
Dealing with Corticosteroid and High-Dose Cyclosporine Therapy in a Pyoderma Gangrenosum Patient Contracting a COVID-19 Infection2022 Journal of Personalized Medicine article Medicine Autoimmune and Inflammatory Disorders Open access
Marcella Ricardis May, Albert Rübben, Andrea Lennertz, Luk Vanstreels, Marike M. Leijs
2citations -
Tolerogenic dendritic cells pulsed with islet antigen induce long-term reduction in T-cell autoreactivity in type 1 diabetes patients2022 Frontiers in Immunology article Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
Tatjana Nikolić, Jessica S. Suwandi, Joris Wesselius, Sandra Laban, Antoinette M. Joosten, Petra Sonneveld, +5 more
51citations -
P191 Efficacy and improvement in patient-reported outcomes at weeks 16 and 52 in ixekizumab treated biological naïve patients with radiographic axial spondyloarthritis achieving clinically important pain at night reduction at week 16: results from COAST-V trial
Sofía Ramiro, Cédric Lukas, Michael John Nissen, Yves Schymura, Khai Jing Ng, Gabriel Doridot, +3 more
0citations -
Real‐world study on fluoropyrimidine‐related toxicity outcomes in cancer patients with select DPYD variant alleles that received DPYD genotype‐guided dosing2025 International Journal of Cancer article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sofía L. J. Peeters, Didier Meulendijks, Zerina Kadric, Sara Ibrovic, Geert‐Jan Creemers, Vanja Milosevic, +7 more
6citations -
Functionality of a next generation biosynthetic bacterial 6-phytase in enhancing phosphorus availability to broilers fed a corn-soybean meal-based diet2020 Animal Feed Science and Technology article Agricultural and Biological Sciences Phytase and its Applications Open access
Yueming Dersjant-Li, Gregory S. Archer, Austin M. Stiewert, A.A. Brown, Eric B. Sobotik, Austin Jasek, +12 more
37citations -
Enhancing synchrotron radiation micro-CT images using deep learning: an application of Noise2Inverse on bone imaging2025 Journal of Synchrotron Radiation article Computer Science Image and Signal Denoising Methods Open access
Yoshihiro Obata, Dilworth Y. Parkinson, Daniël M. Pelt, Claire Acevedo
4citations -
Population Pharmacokinetics of Trimethoprim/Sulfamethoxazole: Dosage Optimization for Patients with Renal Insufficiency or Receiving Continuous Renal Replacement Therapy2024 Clinical Pharmacology & Therapeutics article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Emiel Leegwater, Lauren Baidjoe, Erik B. Wilms, Leo G. Visser, Daan Johannes Touw, Brenda C. M. de Winter, +6 more
12citations -
PFS24 as a prognostic milestone in patients with newly diagnosed primary CNS lymphoma2025 Journal of Hematology & Oncology article Medicine CNS Lymphoma Diagnosis and Treatment Open access
Vanja Zeremski, Tobias Ronny Haage, Hanno Maximilian Witte, Louisa Adolph, Sina Alexandra Beer, Gerhard Behre, +10 more
1citations -
Pharmacokinetics of 5-Fluorouracil in Patients Treated With Capecitabine Carrying the c.1236G>A DPYD Variant Allele2026 JCO Precision Oncology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Niels Heersche, Jonathan Emanuel Knikman, Maarten J. Deenen, Hilde Rosing, Ron H. N. van Schaik, Jos H. Beijnen, +7 more
1citations -
Role of Systemic Glucocorticoids in Reducing IgA and Galactose-Deficient IgA1 Levels in IgA Nephropathy2025 Clinical Journal of the American Society of Nephrology article Medicine Renal Diseases and Glomerulopathies Open access
Jincan Zan, Jingyi Li, Muh Geot Wong, Dana Kim, Sufang Shi, Helen Monaghan, +3 more
8citations -
Survival of patients with colorectal or pancreatic cancer who received UGT1A1 genotype-guided dosing of irinotecan in the Netherlands (2017–2024): a retrospective, multicentre cohort study2026 The Lancet Regional Health - Europe article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sofía L. J. Peeters, Niels Heersche, Doortje T.M.M. Böhm, Stefan Böhringer, Roselien Guiljam, Emma C. Hulshof, +17 more
2citations -
CYP3A4*22 Genotype-Guided Dosing of Kinase Inhibitors in Cancer Patients2023 Clinical Pharmacokinetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Ruben A.G. van Eerden, Nikki S. IJzerman, Milan van Meekeren, Esther Oomen‐de Hoop, Niels A.D. Guchelaar, Andrea M. W. Visser, +10 more
10citations -
The effect of renal impairment and obesity on anti-Xa peak and trough levels in patients receiving therapeutic doses of nadroparin: a comparison with control patients2023 European Journal of Clinical Pharmacology article Medicine Venous Thromboembolism Diagnosis and Management Open access
Logan E. Mast, Mariska Y. M. Peeters, Maaike Söhne, C. M. Hackeng, Catherijne A. J. Knibbe, Marcel P. H. van den Broek
1citations -
UGT1A1 genotype-guided dosing of irinotecan: A prospective safety and cost analysis in poor metaboliser patients2022 European Journal of Cancer article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Emma C. Hulshof, Mirjam de With, Femke M. de Man, Geert‐Jan Creemers, Birgit A. L. M. Deiman, Jesse Joachim Swen, +15 more
57citations