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Early Alterations of RNA Binding Protein (RBP) Homeostasis and ER Stress-Mediated Autophagy Contributes to Progressive Retinal Degeneration in the rd10 Mouse Model of Retinitis Pigmentosa (RP)2023 Cells article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Alfred Yamoah, Priyanka Tripathi, Haihong Guo, Leonie Scheve, Peter Walter, Sandra Johnen, +3 more
12citations -
Multimodal profiling of chordoma immunity reveals distinct immune contextures2024 Journal for ImmunoTherapy of Cancer article Medicine Bone Tumor Diagnosis and Treatments Open access
Siddh van Oost, Debora M. Meijer, Marieke E. Ijsselsteijn, Jessica P Roelands, Brendy E. van den Akker, Ruud van der Breggen, +8 more
21citations -
DNA Methyltransferase 1 (DNMT1) Acts on Neurodegeneration by Modulating Proteostasis-Relevant Intracellular Processes2020 International Journal of Molecular Sciences article Neuroscience Genetic Neurodegenerative Diseases Open access
Cathrin Bayer, Georg Pitschelatow, Nina Hannemann, Jenice Linde, Julia Reichard, Daniel Pensold, +1 more
21citations -
Tub-010, a Novel Antibody-Drug-Conjugate with Reduced Nonspecific Toxicity Profile Based on Tub-Tag Technology Widens the Therapeutic Window for the Treatment of CD30+ Malignancies
Marcus Gerlach, Saskia Schmitt, Philipp Cyprys, Marc‐André Kasper, Isabelle Mai, Maarten H. Vermeer, +5 more
3citations -
Developing HDAC4-Selective Protein Degraders To Investigate the Role of HDAC4 in Huntington’s Disease Pathology2022 Journal of Medicinal Chemistry article Neuroscience Genetic Neurodegenerative Diseases Open access
Natsuko Macabuag, William Esmieu, Perla Breccia, Rebecca E. Jarvis, Wesley Blackaby, Ovadia Lazari, +19 more
34citations -
Immunological Evaluation In Vitro of Nanoparticulate Impurities Isolated From Pharmaceutical-Grade Sucrose2020 Journal of Pharmaceutical Sciences article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access
Adam Grabarek, Myriam Nabhan, Isabelle Turbica, Andrea Hawe, Marc J. Pallardy, Wim Jiskoot
5citations -
scAGG: Sample-level embedding and classification of Alzheimer's disease from single-nucleus data2025 Computational and Structural Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Timo Verlaan, Gerard A. Bouland, Ahmed Essam Mahfouz, Marcel J. T. Reinders
3citations -
An evolutionarily conserved mechanism controls reversible amyloids of pyruvate kinase via pH-sensing regions2024 Developmental Cell article Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Gea Cereghetti, Vera Maria Kissling, Lisa Maria Koch, Alexandra Arm, Claudia C. Schmidt, Yannik Thüringer, +17 more
21citations