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Improved Prediction of CYP2D6 Catalyzed Drug Metabolism by Taking Variant Substrate Specificities and Novel Polymorphic Haplotypes into Account2025 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
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Quantifying Antibody Persistence After a Single Dose of COVID ‐19 Vaccine Ad26. COV2 .S in Humans Using a Mechanistic Modeling and Simulation Approach2022 Clinical Pharmacology & Therapeutics article Medicine SARS-CoV-2 and COVID-19 Research Open access
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Effects of Mexiletine and Lacosamide on Nerve Excitability in Healthy Subjects: A Randomized, Double‐Blind, Placebo‐Controlled, Crossover Study2022 Clinical Pharmacology & Therapeutics article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
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Long‐Read Sequencing Enhances Pharmacogenomic Profiling by Resolving Complex Haplotypes, Novel Star Alleles, and Structural Variants2025 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
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Proof of Concept: First Pediatric [14C]microtracer Study to Create Metabolite Profiles of Midazolam2020 Clinical Pharmacology & Therapeutics article Medicine Pharmaceutical studies and practices Open access
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A Model‐Based Workflow to Benchmark the Clinical Cholestasis Risk of Drugs2021 Clinical Pharmacology & Therapeutics article Medicine Drug Transport and Resistance Mechanisms Open access
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Lower Dose‐Normalized Tacrolimus Exposure in CYP3A5 *6 vs. *3 Loss‐of‐Function Allele Carriers: A Longitudinal Retrospective Real‐World Study in Kidney Transplant Recipients2025 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Amar D. Levens, Dirk Jan A. R. Moes, Yanick Boer, Aiko P. J. de Vries, Dorottya K. de Vries, Danny van der Helm, +5 more
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Therapeutic Orphan No More: Role for Clinical Pharmacology and Translational Science in Developing Therapeutics for Rare and Neglected Diseases2024 Clinical Pharmacology & Therapeutics article Medicine Pharmaceutical studies and practices Open access
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The Changing Face of Oncology Research, Drug Development, and Clinical Practice: Toward Patient‐Focused Precision Therapeutics2020 Clinical Pharmacology & Therapeutics article Mathematics Statistical Methods in Clinical Trials Open access
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Nonlinear Mixed‐Effects Model of Z‐Endoxifen Concentrations in Tamoxifen‐Treated Patients from the CEPAM Cohort2024 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Anna M. Mc Laughlin, Thomas Helland, Fenja Klima, Stijn L.W. Koolen, Ron H. N. van Schaik, Ron H.J. Mathijssen, +16 more
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The Evolution of Drug Regulatory Sciences in the Netherlands: More than a Country Report2024 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmaceutical industry and healthcare Open access
Anna M.G. Pasmooij, Peter G. M. Mol, Jacob Cornelis Bot, Hubert G. M. Leufkens
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TMS and EEG Pharmacodynamic Effects of a Selective Sphingosine‐1‐Phosphate Subtype 1 Receptor Agonist on Cortical Excitability in Healthy Subjects2024 Clinical Pharmacology & Therapeutics article Medicine Epilepsy research and treatment Open access
Catherine M.K.E. de Cuba, Annika A. de Goede, Erica Surya Klaassen, Marije E. Otto, Robert Jan Doll, Jessica J. Kim, +4 more
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Safety, Pharmacokinetics, and Pharmacodynamics of a First‐in‐Class ClC ‐1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial2024 Clinical Pharmacology & Therapeutics article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
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CB1 Receptor Antagonist Selonabant ( ANEB ‐001) Blocks Acute THC Effects in Healthy Volunteers: A Phase II Randomized Controlled Trial2025 Clinical Pharmacology & Therapeutics article Medicine Cannabis and Cannabinoid Research Open access
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