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Viral clearance, pharmacokinetics and tolerability of ensovibep in patients with mild to moderate COVID‐19: A phase 2a, open‐label, single‐dose escalation study2022 British Journal of Clinical Pharmacology article Medicine SARS-CoV-2 and COVID-19 Research Open access
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General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children2022 British Journal of Clinical Pharmacology article Medicine Pharmaceutical studies and practices Open access
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Population pharmacokinetics of roxadustat in Japanese dialysis‐dependent chronic kidney disease patients with anaemia2021 British Journal of Clinical Pharmacology article Medicine Erythropoietin and Anemia Treatment Open access
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Do dimethyl fumarate and nicotinic acid elicit common, potentially HCA2‐mediated adverse reactions? A combined epidemiological‐experimental approach2021 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacovigilance and Adverse Drug Reactions Open access
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Hypokalaemia in patients treated with intravenous flucloxacillin: Incidence and risk factors2022 British Journal of Clinical Pharmacology article Medicine Potassium and Related Disorders Open access
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Population pharmacokinetics and exposure–response analyses of daratumumab plus pomalidomide/dexamethasone in relapsed or refractory multiple myeloma2022 British Journal of Clinical Pharmacology article Medicine Multiple Myeloma Research and Treatments Open access
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Contribution of common and rare genetic variants in CEP72 on vincristine‐induced peripheral neuropathy in brain tumour patients2022 British Journal of Clinical Pharmacology article Medicine Cancer Treatment and Pharmacology Open access
Marije J. Klumpers, Annouk C. A. M. Brand, Marina Hakobjan, Giovanna Gattuso, Elisabetta Schiavello, Monica Terenziani, +5 more
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Effect of hydroxychloroquine on the cardiac ventricular repolarization: A randomized clinical trial2021 British Journal of Clinical Pharmacology article Medicine Cardiac electrophysiology and arrhythmias Open access
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Impact of enantiomer‐specific changes in pharmacokinetics between infants and adults on the target concentration of racemic ketorolac: A pooled analysis2020 British Journal of Clinical Pharmacology article Medicine Pharmaceutical studies and practices Open access
Michael E. Cloesmeijer, Michiel Joost van Esdonk, Anne M Lynn, Anne Smits, Dick Tibboel, Youssef Daali, +3 more
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Towards precision dosing of aripiprazole in children and adolescents with autism spectrum disorder: Linking blood levels to weight gain and effectiveness2023 British Journal of Clinical Pharmacology article Medicine Pharmaceutical studies and practices Open access
Rebecca A. Hermans, Sebastiaan D. T. Sassen, Sanne Maartje Kloosterboer, Catrien G. Reichart, Mirjam E. J. Kouijzer, Matthias M. J. de Kroon, +8 more
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Safety, pharmacokinetics and pharmacodynamics of HTL0009936, a selective muscarinic M1‐acetylcholine receptor agonist: A randomized cross‐over trial2021 British Journal of Clinical Pharmacology article Medicine Cholinesterase and Neurodegenerative Diseases Open access
Samantha Prins, Jan Liptrot, Ellen P. Hart, Erica Surya Klaassen, Giles A. Brown, Alastair Brown, +8 more
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Combined effect of CYP2C19 and CYP2D6 genotypes on escitalopram serum concentration and its metabolic ratio in a European patient population2024 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Pari Faraj, Tore Haslemo, Jenny Phung Tran, Julia Stingl, Espen Molden, Kristine Hole
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Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research2024 British Journal of Clinical Pharmacology article Biochemistry, Genetics and Molecular Biology High Altitude and Hypoxia Open access
Titiaan E. Post, Cayla Denney, Adam F. Cohen, Jens Jordan, Ulrich Limper
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Question‐based development of high‐risk medical devices: A proposal for a structured design and review process2023 British Journal of Clinical Pharmacology article Health Professions Healthcare Regulation Open access
Nicholas A. White, Timo J. C. Oude Vrielink, Koen E.A. van der Bogt, Adam F. Cohen, Joris I. Rotmans, Tim Horeman
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Why we should sample sparsely and aim for a higher target: Lessons from model‐based therapeutic drug monitoring of vancomycin in intensive care patients2020 British Journal of Clinical Pharmacology article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Tingjie Guo, Reinier M. van Hest, Lucas M. Fleuren, Luca F. Roggeveen, Rob J. Bosman, Peter H. J. van der Voort, +4 more
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Dosing of factor VIII concentrate by ideal body weight is more accurate in overweight and obese haemophilia A patients2020 British Journal of Clinical Pharmacology article Medicine Hemophilia Treatment and Research Open access
Iris van Moort, Tim Preijers, Hendrika C. A. M. Hazendonk, Roger E. G. Schutgens, Britta A. P. Laros‐van Gorkom, Laurens Nieuwenhuizen, +6 more
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A phase 1 trial of AP30663, a K Ca 2 channel inhibitor in development for conversion of atrial fibrillation2023 British Journal of Clinical Pharmacology article Medicine Cardiac electrophysiology and arrhythmias Open access
Christina Yfanti, Birgitte Vestbjerg, Juliëtte van 't Westende, Nils G. Edvardsson, Laia Meseguer Monfort, MORTEN SALLING OLESEN, +11 more
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A first step towards best practice recommendations for the design and statistical analyses of pragmatic clinical trials: A modified Delphi approach2022 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Victoria Palin, Tjeerd Pieter van Staa, Stephanie Steels, Andrea B. Troxel, Rolf H. H. Groenwold, Thomas MacLennan MacDonald, +7 more
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Population pharmacokinetics of vancomycin in term neonates with perinatal asphyxia treated with therapeutic hypothermia2024 British Journal of Clinical Pharmacology article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Marlotte A. A. van der Veer, Timo Robert de Haan, Linda G. W. Franken, Reinier M. van Hest, Floris Groenendaal, Peter H. Dijk, +10 more
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Self‐management support with the Respiratory Adherence Care Enhancer instrument in asthma and chronic obstructive pulmonary disease: An implementation trial2024 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacy and Medical Practices Open access
Claire D. Visser, Lisanne L. M. Antonisse, Floor M. Alleda, Privender K. Saini, Esther Kuipers, Henk‐Jan Guchelaar, +1 more
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Randomized placebo‐controlled crossover study to assess tolerability and pharmacodynamics of zagociguat, a soluble guanylyl cyclase stimulator, in healthy elderly2023 British Journal of Clinical Pharmacology article Neuroscience Neurological Disorders and Treatments Open access
Sebastiaan J. W. van Kraaij, Laura G. J. M. Borghans, Erica Surya Klaassen, Pim Gal, Jeroen van der Grond, Ken Tripp, +3 more
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A crossover study evaluating the sex‐dependent and sensitizing effects of sleep deprivation using a nociceptive test battery in healthy subjects2022 British Journal of Clinical Pharmacology article Medicine Pain Mechanisms and Treatments Open access
Hemme J. Hijma, Ingrid W. Koopmans, Erica Surya Klaassen, Robert Jan Doll, Rob G. J. A. Zuiker, Geert Jan Groeneveld
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Validation of a perioperative population factor VIII pharmacokinetic model with a large cohort of pediatric hemophilia a patients2021 British Journal of Clinical Pharmacology article Medicine Hemophilia Treatment and Research Open access
Tim Preijers, Ri J. Liesner, Hendrika C. A. M. Hazendonk, Pratima Chowdary, Mariette H E Driessens, Dan P. Hart, +7 more
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