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Preclinical Evaluation of Trabectedin in Combination With Targeted Inhibitors for Treatment of Metastatic Uveal Melanoma2022 Investigative Ophthalmology & Visual Science article Medicine Ocular Oncology and Treatments Open access
Kseniya Glinkina, Fariba Némati, Amina F.A.S. Teunisse, Maria Chiara Gelmi, Muriel J. Kuipers, Samar Alsafadi, +3 more
6citations -
Heritable transgenic schistosomes as a living platform for SARS-CoV-2 neutralizing antibody secretion2026 Nature Communications article Immunology and Microbiology Parasites and Host Interactions Open access
Wannaporn Ittiprasert, Michael J. Smout, Victoria H. Mann, Matthew Moyle, Sean Kinahan, Daniel N. Ackerman, +20 more
0citations -
Combination of AFP vaccine and immune checkpoint inhibitors slows hepatocellular carcinoma progression in preclinical models2023 Journal of Clinical Investigation article Medicine Cancer Immunotherapy and Biomarkers Open access
Xinjun Lu, Jiejie Xu, Benjamin L. Green, Honghua Zhang, Guofei Cui, Yi Zhang, +10 more
40citations -
Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma2022 Nature Communications article Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access
Karin D. Prummel, Helena Lucia Crowell, Susan Nieuwenhuize, Eline Constance Brombacher, Stephan Daetwyler, Charlotte Soneson, +17 more
39citations -
Long-Lived Human Lymphatic Endothelial Cells to Study Lymphatic Biology and Lymphatic Vessel/Tumor Coculture in a 3D Microfluidic Model2021 ACS Biomaterials Science & Engineering article Medicine Lymphatic System and Diseases Open access
Nicola C. Frenkel, Susanna Poghosyan, Carmen Rubio Alarcon, Silvia Bonilla García, Karla C. S. Queiroz, Lotte van den Bent, +5 more
38citations -
Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood–brain barrier impairment2023 Acta Neuropathologica Communications article Neuroscience Barrier Structure and Function Studies Open access
Narek Manukjan, Daria Majcher, Peter J. A. Leenders, Florian Caiment, Marcel van Herwijnen, Hubert J.M. Smeets, +11 more
31citations -
Autophagic flux inhibition enhances cytotoxicity of the receptor tyrosine kinase inhibitor ponatinib2020 Journal of Experimental & Clinical Cancer Research article Medicine Autophagy in Disease and Therapy Open access cited by 1 patent
Diana Corallo, Fabio Pastorino, Marcella Pantile, Elena Mariotto, Federico Caicci, Giampietro Viola, +3 more
27citations -
SELENOP modifies sporadic colorectal carcinogenesis and WNT signaling activity through LRP5/6 interactions2023 Journal of Clinical Investigation article Biochemistry, Genetics and Molecular Biology Wnt/β-catenin signaling in development and cancer Open access
Jennifer M. Pilat, Rachel E. Brown, Zhengyi Chen, Nathaniel J. Berle, Adrian P. Othon, Mary Kay Washington, +11 more
26citations -
Pulmonary ductal coarctation and left pulmonary artery interruption; pathology and role of neural crest and second heart field during development2020 PLoS ONE article Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Adriana C. Gittenberger–de Groot, Joshua Craiger Peterson, Lambertus J. Wisse, Arno A.W. Roest, Robert E. Poelmann, Regina Bökenkamp, +5 more
15citations -
Purinergic receptor P2X7 regulates interleukin-1α mediated inflammation in chronic kidney disease in a reactive oxygen species-dependent manner2024 Kidney International article Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling Open access
Janina Frisch, Priska Jost, Tamim Sarakpi, Simina‐Ramona Selejan, Ellen Becker, A.B. Sellier, +10 more
15citations -
Efficient Viral Transduction in Fetal and Adult Human Inner Ear Explants with AAV9-PHP.B Vectors2022 Biomolecules article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Edward S. A. van Beelen, Wouter H. van der Valk, Thijs O. Verhagen, John C.M.J. de Groot, Margot A. Madison, Wijs Shadmanfar, +5 more
12citations -
Type I interferon, induced by adenovirus or adenoviral vector infection, regulates the cytokine response to LPS in a macrophage type-specific manner2024 Journal of Innate Immunity article Immunology and Microbiology Immune Response and Inflammation Open access
Mareike D. Maler, Sophie Zwick, Carsten Kallfass, Peggy Engelhard, Hexin Shi, Laura Hellig, +14 more
2citations -
Defining Precystic vs. Cystic Alterations in Pkd1 Renal Mutants2024 Journal of the American Society of Nephrology article Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases
Daniel Spies, Sara Clerici, Marco Chiaravalli, Gangqi Wang, Laura Cassina, Ton J. Rabelink, +1 more
0citations -
Glucose transport dependency defines a therapeutic vulnerability in JAK2V617F-driven myeloproliferative neoplasms2026 Cell Communication and Signaling article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Patrick Weiand, Nicolas Chatain, Marcelo A. S. Toledo, Julia Moellmann, Tabea Pirker, Siddharth Gupta, +7 more
0citations -
Cellular Senescence Is Associated with Disease Progression in ADPKD2025 Journal of the American Society of Nephrology article Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases
Annegien T. Kenter, Sidrah Maryam, Dorien J.M. Peters, Rafael Kramann, Sikander Hayat, Ewout Jasper Hoorn
0citations -
Effects of flow and polycystin‐1 dysfunction on ATP release in the inner medullary collecting duct of the kidney2022 The FASEB Journal article Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases
Wouter H. van Megen, Charlotte R. M. M. van Waes, Dorien J.M. Peters, Jenny van der Wijst, Joost G.J. Hoenderop
0citations