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Combined inhibition of the complement component C5 and the TLR-coreceptor CD14 alters the posttraumatic response in fracture hematoma in a porcine polytrauma model2025 Innovative Surgical Sciences article Immunology and Microbiology Immune Response and Inflammation Open access
Klemens Horst, Ümit Mert, Johannes Greven, Felix Bläsius, Tom Eirik Mollnes, Markus Stefan Huber-Lang, +3 more
0citations -
SPRAYDYE: a phase I/II randomised pilot study to assess the safety and feasibility of topically applied AKRO-6qcICG, a cathepsin-activatable fluorescent imaging agent, for real-time intraoperative resection margin assessment in breast-conserving surgery
Cedric M. W. Pesch, Daan G. J. Linders, Taryn L. March, Martin Pool, A. Rob P.M. Valentijn, Denise E. Hilling, +11 more
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PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling2020 Circulation Research article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Urszula Rykaczewska, Bianca E Suur, Samuel Röhl, Anton Razuvaev, Mariette Lengquist, Maria Sabater‐Lleal, +23 more
66citations -
The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway2021 Cell Reports article Biochemistry, Genetics and Molecular Biology Cellular transport and secretion Open access
Tom Cremer, Marlieke L.M. Jongsma, Fredrik Trulsson, Alfred C.O. Vertegaal, Jacques Neefjes, Ilana Berlin
47citations -
ST3GAL5‐catalyzed gangliosides inhibit TGF‐β‐induced epithelial‐mesenchymal transition via TβRI degradation2022 The EMBO Journal article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Jing Zhang, Gerard van der Zon, Jin Ma, Hailiang Mei, Birol Cabukusta, Cedrick Agaser, +4 more
39citations -
GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice2021 International Journal of Molecular Sciences article Medicine Lysosomal Storage Disorders Research Open access
Martijn J. C. van der Lienden, Jan Aten, André R. A. Marques, Ingeborg S. E. Waas, Per W. B. Larsen, Nike Claessen, +4 more
36citations -
Eosinophils and Purinergic Signaling in Health and Disease2020 Frontiers in Immunology article Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling Open access
Davide Ferrari, Marta Vuerich, Fabio Casciano, Maria Serena Longhi, Elisabetta Melloni, Paola Secchiero, +4 more
28citations -
C2orf69 mutations disrupt mitochondrial function and cause a multisystem human disorder with recurring autoinflammation2021 Journal of Clinical Investigation article Biochemistry, Genetics and Molecular Biology Mitochondrial Function and Pathology Open access
Eva Lausberg, Sebastian Gießelmann, Joseph P. Dewulf, Elsa Wiame, Anja Holz, Ramona Salvarinova, +27 more
23citations -
Opposing USP19 splice variants in TGF-β signaling and TGF-β-induced epithelial–mesenchymal transition of breast cancer cells2023 Cellular and Molecular Life Sciences article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Jing Zhang, Maarten van Dinther, Midory Thorikay, Babak Mousavi Gourabi, Boudewijn P. T. Kruithof, Peter ten Dijke
20citations -
Targeting Sphingosine-1-Phosphate Signaling to Prevent the Progression of Aortic Valve Disease2024 Circulation article Biochemistry, Genetics and Molecular Biology Sphingolipid Metabolism and Signaling
Marcel Benkhoff, Maike Barcik, Philipp Mourikis, Jana Dahlmanns, Paulina Kahmann, Philipp Wollnitzke, +28 more
15citations -
Highly Specific Miniaturized Fluorescent Monoacylglycerol Lipase Probes Enable Translational Research2025 Journal of the American Chemical Society article Medicine Cannabis and Cannabinoid Research Open access
Axel Hentsch, Mónica Guberman, Silke Radetzki, Mirjam C. W. Huizenga, Yingfang He, Jörg Contzen, +18 more
12citations -
T Cell Responses to Dystrophin in a Natural History Study of Duchenne Muscular Dystrophy2022 Human Gene Therapy article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Karen Anthony, Pierpaolo Ala, Francesco Catapano, Jinhong Meng, Joana Domingos, Mark M. Perry, +15 more
12citations -
Deciphering non-canonical ubiquitin signaling: biology and methodology2024 Frontiers in Molecular Biosciences article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Nila K. van Overbeek, Tim Aguirre, Gerbrand J. van der Heden van Noort, Blagoy Blagoev, Alfred C.O. Vertegaal
11citations -
Deubiquitinases in muscle physiology and disorders2024 Biochemical Society Transactions article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Cyriel Sebastiaan Olie, Darragh Patrick O'Brien, Hannah B. L. Jones, Zhu Liang, Andreas Damianou, İlknur Sur‐Erdem, +3 more
8citations