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Drug Distribution in Brain and Cerebrospinal Fluids in Relation to IC50 Values in Aging and Alzheimer’s Disease, Using the Physiologically Based LeiCNS-PK3.0 Model2022 Pharmaceutical Research article Medicine Cholinesterase and Neurodegenerative Diseases Open access
Mohammed A. A. Saleh, Julia S. Bloemberg, Jeroen Elassaiss‐Schaap, Elizabeth C. M. de Lange
8citations -
Normothermic Machine Perfusion in a Porcine Donation After Brain Death Autotransplantation Model with the Fully Synthetic Perfusate Omnisol: A Feasibility Study2026 American Journal of Transplantation article Medicine Organ Transplantation Techniques and Outcomes
L. Ernst, A. Zare, W. Liu, J. Knorr, Christian Bleilevens, Oliver Beetz, +7 more
0citations -
Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice2023 Pharmaceutical Research article Neuroscience Barrier Structure and Function Studies Open access
Mohammed A. A. Saleh, Berfin Gülave, Olivia Campagne, Clinton F. Stewart, Jeroen Elassaiss‐Schaap, Elizabeth C. M. de Lange
5citations -
Normative modelling of brain morphometry across the lifespan with CentileBrain: algorithm benchmarking and model optimisation2024 The Lancet Digital Health article Neuroscience Functional Brain Connectivity Studies Open access
Ruiyang Ge, Yuetong Yu, Yi Xuan Qi, Yunan Vera Fan, Shiyu Chen, Chuntong Gao, +38 more
118citations -
Ensemble graph neural network model for classification of major depressive disorder using whole-brain functional connectivity2023 Frontiers in Psychiatry article Neuroscience Functional Brain Connectivity Studies Open access cited by 1 patent
Sujitha Venkatapathy, Mikhail Votinov, Lisa Wagels, SangYun Kim, Munseob Lee, Ute Habel, +2 more
44citations -
Do Brain Extracellular Fluid Concentrations Predict PET ‐Inferred Receptor Occupancy in Human CNS ? A Mechanistic Model‐Based Analysis of Dopamine D2 Receptor Ligands2026 Clinical Pharmacology & Therapeutics article Neuroscience Neurotransmitter Receptor Influence on Behavior Open access
Divakar Budda, J. G. Coen van Hasselt, Elizabeth C. M. de Lange
0citations -
Normative Modeling of Brain Morphometry Across the Lifespan Using CentileBrain: Algorithm Benchmarking and Model Optimization2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Functional Brain Connectivity Studies Open access
Ruiyang Ge, Yuetong Yu, Yi Xuan Qi, Yunan Vera Fan, Shiyu Chen, Chuntong Gao, +92 more
21citations -
Prediction of the Extent of Blood–Brain Barrier Transport Using Machine Learning and Integration into the LeiCNS-PK3.0 Model2025 Pharmaceutical Research article Computer Science Computational Drug Discovery Methods Open access
Berfin Gülave, Helle W. van den Maagdenberg, Luke van Boven, Gerard J. P. van Westen, Elizabeth C. M. de Lange, J. G. Coen van Hasselt
7citations -
Multimodal imaging of hair follicle bulge-derived stem cells in a mouse model of traumatic brain injury2020 Cell and Tissue Research article Medicine Traumatic Brain Injury and Neurovascular Disturbances Open access
Timo Schomann, Juvita Delancy Iljas, Ivo Que, Yuedan Li, Ernst Suidgeest, Luis Javier Cruz, +5 more
4citations -
Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy2021 Nature Communications article Immunology and Microbiology interferon and immune responses Open access
Matthias Kettwig, Katharina Ternka, Kristin Wendland, Silvia Zampar, Charlotte Schob, Jonas Franz, +20 more
40citations -
From injury to degeneration: delayed lipid-mediated neurotoxicity in a human astrocyte traumatic brain injury in-a-dish model2026 Cell Death and Disease article Medicine Traumatic Brain Injury and Neurovascular Disturbances Open access
Luise Schlotterose, Michel A. Struwe, Axel J. Scheidig, Niek Blomberg, Martin A. Giera, Kirsten Hattermann, +1 more
0citations -
Gut microbiota and brain alterations in a translational anorexia nervosa rat model2020 Journal of Psychiatric Research article Biochemistry, Genetics and Molecular Biology Gut microbiota and health
Stefanie Trinh, Vanessa Kogel, Clara Voelz, Constanze Schwenzer, Johanna Kabbert, Nicole Maria Heussen, +4 more
40citations -
Neuroprotective Effects Of The Inert Gas Argon Onexperimental Traumatic Brain Injury In Vivo With The Controlled Cortical Impact Model In Mice2021 Research Square preprint Medicine Traumatic Brain Injury and Neurovascular Disturbances Open access
Fritz I. Schneider, Sandro Manuel Krieg, Ute Lindauer, Michael Hubert Stoffel, Yu‐Mi Ryang
0citations -
NOTCH3 active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cerebrovascular and genetic disorders Open access
Daniel V. Oliveira, Kirsten Coupland, Shaobo Jin, Francesca Del Gaudio, Sailan Wang, Rhys Fox, +6 more
0citations