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A modular Uba1-nanobody fusion enables selective ubiquitin transfer to tagged E2 enzymes2025 Journal of Biological Chemistry article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Charlotte Wijne, Francesca D’Amico, David A. Pérez Berrocal, Monique P. C. Mulder, Hidde L. Ploegh
1citations -
β- d -Arabinofuranose-configured Cyclitol Aziridines as Selective, Brain-penetrant Covalent GBA2 Inhibitors2026 Journal of the American Chemical Society article Medicine Lysosomal Storage Disorders Research Open access
Rob F. Lammers, Qin Su, Laura Mazo, Wendy A. Offen, Roelof Ottenhoff, Mats J. Bulterman, +16 more
0citations -
β-D-Arabinofuranose-configured cyclitol aziridines as selective, brain-penetrant covalent GBA2 inhibitors2026 White Rose Research Online (University of Leeds, The University of Sheffield, University of York) article Medicine Lysosomal Storage Disorders Research Open access
Rob F. Lammers, Qin Su, Laura Mazo, Wendy A. Offen, Roelof Ottenhoff, Mats J. Bulterman, +16 more
0citations -
Chemoproteomic mapping of active glycan-processing networks in a defined gut microbiome2026 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Isabelle B. Pickles, Thamy Lívia Ribeiro Côrrea, Qinnan Yang, Yurong Chen, Zirui Li, Nicole M. Koropatkin, +3 more
0citations -
Skin barrier lipid enzyme activity in Netherton patients is associated with protease activity and ceramide abnormalities2020 Journal of Lipid Research article Biochemistry, Genetics and Molecular Biology Genetic and rare skin diseases. Open access cited by 1 patent
Jeroen van Smeden, Hanin Al-Khakany, Yichen Wang, Dani Visscher, Samira Absalah, Herman S. Overkleeft, +3 more
29citations -
PhenoSelection Manuscript 16S amplicons2023 OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) article Environmental Science Microbial Community Ecology and Physiology Open access
Nicholas J. Reichart, Andrea K. Steiger, Elise M. Van Fossen, Ryan McClure, Herman S Overkleeftf, Aaron Wright
0citations -
Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA2022 Journal of the American Chemical Society article Medicine Antimicrobial Resistance in Staphylococcus Open access
Alexander T. Bakker, Ioli Kotsogianni, Liza Mirenda, Verena M. Straub, Mariana Ávalos, Richard J. B. H. N. van den Berg, +5 more
39citations -
Biochemical and Cellular Characterization of the Function of Fluorophosphonate-Binding Hydrolase H (FphH) in Staphylococcus aureus Support a Role in Bacterial Stress Response2023 ACS Infectious Diseases article Biochemistry, Genetics and Molecular Biology Bacterial Genetics and Biotechnology Open access
Matthias Fellner, Stephen Dela Ahator, Nadia Aftab, Eng Wui Tan, Alexander T. Bakker, Nathaniel I. Martin, +2 more
16citations -
HEPES‐buffering of bicarbonate‐containing culture medium perturbs lysosomal glucocerebrosidase activity2022 Journal of Cellular Biochemistry article Medicine Lysosomal Storage Disorders Research Open access
Martijn J. C. van der Lienden, Jan Aten, Rolf G. Boot, Marco van Eijk, Johannes M. F. G. Aerts, C.J. Kuo
6citations -
High Immunoproteasome Activity and sXBP1 in Pediatric Precursor B-ALL Predicts Sensitivity towards Proteasome Inhibitors2021 Cells article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Lenka Bešše, Andrej Bešše, Marianne Kraus, Elmer Maurits, Herman S. Overkleeft, Beat C. Bornhauser, +2 more
7citations -
Complementary chemical probes and substrates reveal split subsite specificity in a fungal GH12 glucanase2026 ChemRxiv preprint Agricultural and Biological Sciences Polysaccharides and Plant Cell Walls Open access
Thamy L R Corrêa, Nicholas G. S. McGregor, Casper de Boer, Sybrin P. Schröder, Quentin P. O. Foucart, Lianne I. Willems, +4 more
0citations -
Inhibiting UCH-L5: Rational Design of a Cyclic Ubiquitin-Based Peptide Inhibitor2022 Frontiers in Molecular Biosciences article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Dharjath S. Hameed, Huib Ovaa, Gerbrand J. van der Heden van Noort, Ayşegül Sapmaz
2citations -
Bacteroides fragilis fucosidases facilitate growth and invasion of Campylobacter jejuni in the presence of mucins2020 Cellular Microbiology article Agricultural and Biological Sciences Salmonella and Campylobacter epidemiology Open access
Yvette M. C. A. Luijkx, N Bleumink, Jianbing Jiang, Herman S. Overkleeft, Marc M. S. M. Wösten, Karin Strijbis, +1 more
32citations -
Cultured Macrophage Models for the Investigation of Lysosomal Glucocerebrosidase and Gaucher Disease2025 International Journal of Molecular Sciences article Medicine Lysosomal Storage Disorders Research Open access
Max Louwerse, Kateryna O. Bila, Martijn J. C. van der Lienden, Arnout Jan de Beaufort, Rolf G. Boot, Marta Artola, +2 more
7citations -
LIMP-2 deficiency-associated glycolipid abnormalities in mice2025 Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids article Medicine Lysosomal Storage Disorders Research Open access
Paulo Gaspar, André R. A. Marques, Maria J. Ferraz, Markus Daμμe, Gertjan Kramer, Mina Mirzaian, +9 more
0citations -
Ubiquitin ligation to F-box protein targets by SCF–RBR E3–E3 super-assembly2021 Nature article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access cited by 1 patent
Daniel Horn‐Ghetko, David T. Krist, Jesuraj Rajan Prabu, Kheewoong Baek, Monique P. C. Mulder, Maren Klügel, +4 more
205citations -
USP16 is an ISG15 cross-reactive deubiquitinase targeting a subset of metabolic pathway-related proteins2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Adán Pinto-Fernández, Dennis Flierman, Jimmy J.L.L. Akkermans, Darragh Patrick O'Brien, Helene Greenwood, Hannah Claire Scott, +8 more
3citations