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Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment2024 ALTEX article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Steven J. Kunnen, Emma Arnesdotter, Christian Tobias Willenbockel, Mathieu Vinken, Bob van de Water
5citations -
Hypotaurine Reduces Glucose‐Mediated Vascular Calcification2025 Acta Physiologica article Biochemistry, Genetics and Molecular Biology Aldose Reductase and Taurine Open access
Marina Augusto Heuschkel, Armand M. G. Jaminon, Steffen Gräber, Anna Artati, Jerzy Adamski, Joachim Jankowski, +4 more
5citations -
Targeting Modulated Vascular Smooth Muscle Cells in Atherosclerosis via FAP-Directed Immunotherapy2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Junedh Amrute, In‐Hyuk Jung, Tracy Yamawaki, Andrea L. Bredemeyer, Johanna Diekmann, Sikander Hayat, +28 more
5citations -
Pulmonary Microvascular Endothelial Cells Support Alveolar Epithelial Growth via Bone Morphogenetic Protein 6 Secretion2025 American Journal of Respiratory Cell and Molecular Biology article Medicine Neonatal Respiratory Health Research Open access
Luke van der Koog, Dyan F. Nugraha, Abilash Ravi, Justina Clarinda Wolters, Peter L. Horvatovich, Ken R. Bracke, +6 more
5citations -
Aberrant and ectopic cell populations in restrictive allograft syndrome after lung transplantation2026 European Respiratory Journal article Medicine Transplantation: Methods and Outcomes Open access
Lena Maureen Leiber, Leonard Christian, Lavinia Neubert, Jannik Ruwisch, Hande Yilmaz, Edith Katharina Plucinski, +25 more
4citations -
MASI enables fast model-free standardization and integration of single-cell transcriptomics data2023 Communications Biology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Yang Xu, Rafael Kramann, Rachel Patton McCord, Sikander Hayat
4citations -
Patient‐derived xenograft mouse models to investigate tropism to the central nervous system and retina of primary and secondary central nervous system lymphoma2023 Neuropathology and Applied Neurobiology article Medicine CNS Lymphoma Diagnosis and Treatment Open access
Lisa Kristina Isbell, Cordula Tschuch, Soroush Doostkam, Silvia Waldeck, Geoffroy Andrieux, Khalid Shoumariyeh, +15 more
4citations -
Intersecting single-cell transcriptomics and genome-wide association studies identifies crucial cell populations and candidate genes for atherosclerosis2021 medRxiv preprint Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Lotte Slenders, Lennart P. L. Landsmeer, Kai Cui, Marie A.C. Depuydt, Maarten C. Verwer, Joost M. Mekke, +17 more
4citations -
Epigenetic and Transcriptional Shifts in Human Neural Stem Cells after Reprogramming into Induced Pluripotent Stem Cells and Subsequent Redifferentiation2024 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Carolin Haubenreich, Andreas Schuppert, Michael Peitz, Philipp Koch, Martin Zenke, Oliver Brüstle
4citations -
Claudin-1 Is a Therapeutic Target for Crescentic Glomerulonephritis2023 Journal of the American Society of Nephrology conference-abstract Medicine Renal Diseases and Glomerulopathies
Geoffrey Teixeira, Jean‐Daniel Delbet, Vincent Anquetil, Alberto Toso, Stephen Toovey, Luigi Manenti, +11 more
4citations -
GRIDGENE: Guided Region Identification based on Density of GENEs – a transcript density-based approach to characterize tissues by spatial transcriptomics2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Ana Marta Sequeira, Marieke E. Ijsselsteijn, Miguel Rocha, Jessica P Roelands, Noel F.C.C. de Miranda
3citations -
Unraveling the spatial landscape of dystrophinopathies: a transcriptomic approach to Becker and Duchenne muscular dystrophies2026 The Journal of Pathology article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
L. Heezen, Stefan Nicolau, Claudio Novella-Rausell, Julia van der Weerd, Jan Kueckelhaus, Jordi Díaz‐Manera, +7 more
3citations -
Transcriptomic mapping of the inter-individual variability of cellular stress response activation in primary human hepatocytes2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Marije Niemeijer, Witold Więcek, Suzanna Huppelschoten, Peter Bouwman, Audrey Baze, Celine Parmentier, +4 more
3citations -
Cytotoxic T cell recognition of α-synuclein drives pathogenic immune responses in multiple system atrophy2026 Proceedings of the National Academy of Sciences article Medicine Parkinson's Disease Mechanisms and Treatments Open access
Jae‐Seung Moon, Salvinaz Islam Moutusy, Mengrui Zhang, Alain Ndayisaba, Diego Rodriguez, Daniel N. El Kodsi, +12 more
3citations -
CEACAM6 Promotes Lung MetastasisviaEnhancing Proliferation, Migration and Suppressing Apoptosis of Prostate Cancer Cells2024 Cancer Genomics & Proteomics article Medicine Prostate Cancer Treatment and Research Open access
Alireza Azizi Saraji, Janine Stegmann-Frehse, Duan Kang, Anne Offermann, GEVORG SHAGHOYAN, Danny David Jonigk, +4 more
3citations -
Immunomodulatory endothelial cells contribute to T-cell recruitment and activation via antigen presentation on MHC II2026 Cardiovascular Research article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases
Matteo Cartura, Blerina Aliraj, Witold G. Szymanski, C.-S. Park, Giulio Ferrario, Flávia Rezende, +15 more
3citations -
Aberrant and Ectopic Cell Populations of the Fibrotic Pushing Border in Restrictive Allograft Syndrome after Lung Transplantation2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Transplantation: Methods and Outcomes Open access
Lena Maureen Leiber, Leonard Christian, Lavinia Neubert, Jannik Ruwisch, Hande Yilmaz, Edith Katharina Plucinski, +22 more
2citations -
Spatial profiling of the spleen in mouse and human myelofibrosis reveals complement-driven immune-stromal interactions as a therapeutic target2026 Cell stem cell article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Bérénice Dugué, Pia Wanner, Mayra L. Ruiz Tejada Segura, Mohamed Saad, Lucas Greven, Katrin Götz, +33 more
2citations