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Local release of siRNA using polyplex-loaded thermosensitive hydrogels2020 Nanoscale article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Lies A. L. Fliervoet, Heyang Zhang, Emma van Groesen, Kyra Fortuin, Naut J. C. B. Duin, Katrien Remaut, +3 more
43citations -
Targeting Activated Hepatic Stellate Cells Using Collagen-Binding Chitosan Nanoparticles for siRNA Delivery to Fibrotic Livers2020 Pharmaceutics article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Menna Azzam, Sara Elsafy, Sarah A. Abdelgelil, Ralf Weiskirchen, Anastasia Asimakopoulou, Federica De Lorenzi, +3 more
40citations -
Together is Better: mRNA Co‐Encapsulation in Lipoplexes is Required to Obtain Ratiometric Co‐Delivery and Protein Expression on the Single Cell Level2021 Advanced Science article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Heyang Zhang, Jeroen Bussmann, Florian Hendric Huhnke, Joke Devoldere, An‐Katrien Minnaert, Wim Jiskoot, +6 more
37citations -
Peptide-Modified Lipid Nanoparticles Boost the Antitumor Efficacy of RNA Therapeutics2025 ACS Nano article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Gangyin Zhao, Ye Zeng, Wanli Cheng, Sofia Karkampouna, Panagiota Papadopoulou, Bochuan Hu, +7 more
37citations -
Multicompartment Polyion Complex Micelles Based on Triblock Polypept(o)ides Mediate Efficient siRNA Delivery to Cancer‐Associated Fibroblasts for Antistromal Therapy of Hepatocellular Carcinoma2024 Advanced Materials article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Paul M. Schneider, Heyang Zhang, Leon Simić, Barbara Schrörs, Özlem Akilli‐Öztürk, Lin Jian, +14 more
33citations -
On the Influence of Fabrication Methods and Materials for mRNA‐LNP Production: From Size and Morphology to Internal Structure and mRNA Delivery Performance In Vitro and In Vivo2024 Advanced Healthcare Materials article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Dongdong Bi, Christoph Wilhelmy, Dennis Unthan, Isabell Sofia Keil, Bonan Zhao, Bastian Kolb, +11 more
25citations -
The N=1 Collaborative: advancing customized nucleic acid therapies through collaboration and data sharing2025 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Jillian Belgrad, Erin M. McConnell, Nicole Nolen, Marlen C. Lauffer, Jonathan K. Watts, Timothy W. Yu, +2 more
25citations -
Biological recognition and cellular trafficking of targeted RNA-lipid nanoparticles2023 Current Opinion in Biotechnology review Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Oscar Escalona-Rayo, Panagiota Papadopoulou, Bram Slütter, Alexander Kros
25citations -
Targeting Ligand Independent Tropism of siRNA‐LNP by Small Molecules for Directed Therapy of Liver or Myeloid Immune Cells2023 Advanced Healthcare Materials article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access cited by 1 patent
Cheng Lin, Alexander Jans, Justina Clarinda Wolters, Mohamed Ramadan Mohamed, Emiel P. C. van der Vorst, Christian Trautwein, +1 more
24citations -
Development of a Combined Lipid-Based Nanoparticle Formulation for Enhanced siRNA Delivery to Vascular Endothelial Cells2022 Pharmaceutics article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access cited by 3 patents
Yutong He, Dongdong Bi, Josée A. Plantinga, Grietje Molema, Jeroen Bussmann, Jan A. A. M. Kamps
23citations -
Small interfering RNA–mediated allele-selective silencing of von Willebrand factor in vitro and in vivo2023 Blood Advances article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Yvonne K. Jongejan, Elisa Schrader Echeverri, Richard J. Dirven, Kalina Paunovska, Noa A. Linthorst, Annika de Jong, +5 more
20citations -
Cellular uptake of modified mRNA occurs via caveolae-mediated endocytosis, yielding high protein expression in slow-dividing cells2023 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Claudia Del Toro Runzer, Shivesh Anand, Carlos Mota, Lorenzo Moroni, Christian Plank, Martijn van Griensven, +1 more
19citations -
Delivery of siHIF‐1α to Reconstruct Tumor Normoxic Microenvironment for Effective Chemotherapeutic and Photodynamic Anticancer Treatments2021 Small article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Xiaobing Chen, Rongrong Jin, Qian Jiang, Qunjie Bi, Ting He, Xu Song, +4 more
19citations -
OSWG Recommended Approaches to the Nonclinical Pharmacokinetic (ADME) Characterization of Therapeutic Oligonucleotides2023 Nucleic Acid Therapeutics article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Madeleine Antonsson, Sándor Bátkai, Sieto Bosgra, Girish Rajmal Chopda, Wouter H. P. Driessen, Jeffrey W.-D. Foy, +8 more
18citations -
A novel targeted co-delivery system for transfer of epirubicin and antimiR-10b into cancer cells through a linear DNA nanostructure consisting of FOXM1 and AS1411 aptamers2021 Journal of Drug Delivery Science and Technology article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery
Elnaz Yaghoobi, Saeed Shojaee, Mohammad Ramezani, Mona Alibolandi, Fahimeh Charbgoo, Morteza Alinezhad Nameghi, +4 more
17citations -
NANOSPRESSO: toward personalized, locally produced nucleic acid nanomedicines2025 Frontiers in Science article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Mariona Estapé Sentí, Alexandre Ceccaldi, Nadine Saber, Paul J. L. Schürmann, Maurits Geerlings, Peter Hölig, +15 more
16citations -
The application of M12L24 nanocages as cell-specific siRNA delivery agents in vitro2023 Chem article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Eduard O. Bobylev, Ye Zeng, Kevin Weijgertse, Emma Koelman, Bas de Bruin, Alexander Kros, +1 more
16citations -
Efficient Downregulation of Alk4 in Skeletal Muscle After Systemic Treatment with Conjugated siRNAs in a Mouse Model for Duchenne Muscular Dystrophy2022 Nucleic Acid Therapeutics article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Sarah Engelbeen, Svetlana Pasteuning-Vuhman, Rubina Giare Parmar, Klaus Charissé, Laura Sepp‐Lorenzino, Muthiah A. Manoharan, +2 more
14citations -
Divergent Delivery and Expression Kinetics of Lipid and Polymeric Nanoparticles across mRNA Modalities2025 Advanced Science article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Irafasha C. Casmil, Josh J. Friesen, Nuthan Vikas Bathula, Anneke Strumpel, Chia-Hao Ho, Ilana Guez, +7 more
12citations -
Cross‐Linkable Polyion Complex Micelles from Polypept(o)ide‐Based ABC‐Triblock Copolymers for siRNA Delivery2021 Macromolecular Rapid Communications article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Leon Capelôa, Mina Yazdi, Heyang Zhang, Xiaobing Chen, Yu Nie, Ernst Wagner, +2 more
12citations -
Integrated and dual-responsive lipopeptide nanovector with parallel effect to tumor and micro-environment regulation by efficient gene and drug co-delivery2022 Chinese Chemical Letters article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Xiaobing Chen, Huan Yang, Xu Song, Hong Liang, Yu Wei, Jiao Lu, +3 more
11citations -
Culture medium used during small interfering RNA (siRNA) transfection determines the maturation status of dendritic cells2020 Journal of Immunological Methods article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Mieke F. van Essen, Nicole Schlagwein, Daniëlle J. van Gijlswijk‐Janssen, Jacqueline D.H. Anholts, Michael Eikmans, Jurjen M. Ruben, +1 more
11citations -
Targeted Delivery of Anti-TGF-β 1 -siRNA Using PDGFR-β Peptide-Modified Chitosan Nanoparticles for the Treatment of Liver Fibrosis2025 Molecular Pharmaceutics article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery
Maryam A. Shetab Boushehri, Aya A. Ezzat, Ralf Weiskirchen, Alf Lamprecht, Samar Mansour, Salma Nabil Tammam
10citations