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Nucleotide excision repair leaves a mark on chromatin: DNA damage detection in nucleosomes2021 Cellular and Molecular Life Sciences article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Katja Apelt, Hannes Lans, Orlando D. Schärer, Martijn S. Luijsterburg
43citations -
The selection process of licensing a DNA mismatch for repair2021 Nature Structural & Molecular Biology article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Rafael Fernández-Leiro, Doreth Bhairosing-Kok, Vladislav Kunetsky, Charlie Laffeber, Herrie H. K. Winterwerp, Flora S. Groothuizen, +5 more
42citations -
ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination2022 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Katja Apelt, Seong-Ok Lee, Hsin‐Ru Chan, Martijn S. Luijsterburg, Justin W. C. Leung, Kyle M. Miller
39citations -
Small tandem DNA duplications result from CST-guided Pol α-primase action at DNA break termini2021 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Joost Schimmel, Núria Muñoz-Subirana, Hanneke Kool, Robin van Schendel, Marcel Tijsterman
38citations -
ERCC1mutations impede DNA damage repair and cause liver and kidney dysfunction in patients2020 The Journal of Experimental Medicine article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Katja Apelt, Susan M. White, Hyun Suk Kim, Jung-Eun Yeo, Annelotte P. Wondergem, Martin A. Rooimans, +13 more
36citations -
Helicase Q promotes homology-driven DNA double-strand break repair and prevents tandem duplications2021 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access cited by 1 patent
Juliette A. Kamp, Bennie B. L. G. Lemmens, Ron J Romeijn, S. C. Changoer, Robin van Schendel, Marcel Tijsterman
35citations -
PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks2020 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Ignacio Alonso‐de Vega, Maria Cristina Paz‐Cabrera, Magdalena B. Rother, Wouter W. Wiegant, Cintia Checa-Rodríguez, Juan Ramon Hernandez-Fernaud, +4 more
35citations -
The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks2024 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Bert van de Kooij, Fenna J. van der Wal, Magdalena B. Rother, Wouter W. Wiegant, Pau Creixell, Merula Stout, +6 more
29citations -
XPC–PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair2022 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Charlotte Blessing, Katja Apelt, Diana van den Heuvel, Claudia Gonzalez-Leal, Magdalena B. Rother, Melanie van der Woude, +16 more
28citations -
BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis2024 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Daniel Salas‐Lloret, Néstor García‐Rodríguez, Emily Soto-Hidalgo, Lourdes González-Vinceiro, Carmen Espejo-Serrano, Lisanne Giebel, +6 more
26citations -
RNF212B E3 ligase is essential for crossover designation and maturation during male and female meiosis in the mouse2024 Proceedings of the National Academy of Sciences article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Yazmine B. Condezo, Raquel Sainz-Urruela, Laura Gómez-H, Daniel Salas‐Lloret, Natalia Felipe‐Medina, Rachel A. Bradley, +11 more
25citations -
Physical interactions between MCM and Rad51 facilitate replication fork lesion bypass and ssDNA gap filling by non-recombinogenic functions2021 Cell Reports article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Maria Jose Cabello-Lobato, Cristina González‐Garrido, María I. Cano-Linares, Ronald P.C. Wong, Aurora Yáñez‐Vilches, Macarena Morillo‐Huesca, +5 more
23citations -
A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair2023 Proceedings of the National Academy of Sciences article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Diana van den Heuvel, Mihyun Kim, Annelotte P. Wondergem, Paula J. van der Meer, Myrèse Witkamp, Ferdy Lambregtse, +10 more
21citations -
Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair2022 Nature Structural & Molecular Biology article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Alessandro Borsellini, Vladislav Kunetsky, Peter Friedhoff, Meindert Hugo Lamers
21citations -
SCAI promotes error‐free repair of DNA interstrand crosslinks via the Fanconi anemia pathway2022 EMBO Reports article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Lisa A. Schubert, Ivo Alexander Hendriks, Emil Peter Thrane Hertz, Wei Wu, Selene Sellés‐Baiget, Saskia Hoffmann, +13 more
19citations -
The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics2024 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Diana A. Llerena Schiffmacher, Shun-Hsiao Lee, Katarzyna W. Kliza, Arjan F. Theil, Masaki Akita, Angela Helfricht, +14 more
19citations -
Translesion synthesis polymerases are dispensable for C. elegans reproduction but suppress genome scarring by polymerase theta-mediated end joining2020 PLoS Genetics article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Ivo van Bostelen, Robin van Schendel, Ron J Romeijn, Marcel Tijsterman
18citations