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Adverse Drug Reactions in the Emergency Department: Is There a Role for Pharmacogenomic Profiles at Risk?—Results from the ADRED Study2020 Journal of Clinical Medicine article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Katja Susanne Just, Harald Dormann, Marlen Schurig, Miriam Böhme, Jochen Fracowiak, Michael Steffens, +5 more
19citations -
Dutch pharmacogenetics working group guideline for the gene-drug interaction of ABCG2, HLA-B and Allopurinol, and MTHFR, folic acid and methotrexate2022 European Journal of Human Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Karel H. van der Pol, Marga Nijenhuis, Bianca Soree, Nienke J. de Boer‐Veger, Anne Marie Buunk, Henk‐Jan Guchelaar, +9 more
37citations -
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6, CYP2C19 and non-SSRI/non-TCA antidepressants2024 European Journal of Human Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Lianne Beunk, Marga Nijenhuis, Bianca Soree, Nienke J. de Boer‐Veger, Anne‐Marie Buunk, Henk‐Jan Guchelaar, +8 more
24citations -
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene–drug interaction between CYP2D6 and CYP2C19 and tricyclic antidepressants2026 European Journal of Human Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Kristian Kleine Schaars, Marga Nijenhuis, Bianca Soree, Nienke J. de Boer‐Veger, Anne‐Marie Buunk, Henk‐Jan Guchelaar, +8 more
8citations -
Challenges associated with dapsone for leprosy treatment in Indonesia - urgent need for access to alternative antimicrobial drugs2025 The Lancet Regional Health - Southeast Asia article Medicine Leprosy Research and Treatment Open access
Hana Krismawati, Maria Harianja, Antonius Oktavian, Claus Bøgh, Messe R Ataupah, Ruth D Laiskodat, +7 more
4citations -
Pharmacogenomics-guided personalized medicine in a clinical setting: real-world data2025 Pharmacogenetics and Genomics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Jiayi Liang, Rikje Ruiter, Pieter Willem Smit, Cornelis F. Vos, Joris J. B. van der Vlugt, Ismaïl Aarab, +3 more
2citations -
Pharmacogenetics-guided dalcetrapib therapy after an acute coronary syndrome: the dal-GenE trial2022 European Heart Journal article Medicine Lipoproteins and Cardiovascular Health Open access cited by 1 patent
Jean‐Claude Tardif, Marc Alan Pfeffer, Simon Kouz, Wolfgang Köenig, Aldo Pietro Maggioni, John J.V. McMurray, +11 more
39citations -
Genetic Susceptibility to Clozapine-Induced Agranulocytosis/Neutropenia Across Ethnicities: Results From a New Cohort of Turkish and Other Caucasian Participants, and Meta-Analysis2020 Schizophrenia Bulletin Open article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Cynthia Okhuijsen‐Pfeifer, Yavuz Ayhan, Bochao Danae Lin, Kristel R. van Eijk, Erwin Bekema, Lindy Kool, +27 more
9citations -
Multinational cost-utility analysis of panel-based pharmacogenetics-guided treatment of patients enrolled in the U-PGx PREPARE study2025 EClinicalMedicine article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Vasileios Fragoulakis, Jesse Joachim Swen, Margarita-Ioanna Koufaki, Kathrin Blagec, Tanja Blagus, Stefan Böhringer, +35 more
7citations -
Generating evidence for precision medicine: considerations made by the Ubiquitous Pharmacogenomics Consortium when designing and operationalizing the PREPARE study2020 Pharmacogenetics and Genomics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Cathelijne H. van der Wouden, Stefan Böhringer, Erika Cecchin, Ka-Chun Cheung, Cristina Lucía Dávila-Fajardo, Vera H.M. Deneer, +20 more
44citations -
CYP2B6 Functional Variability in Drug Metabolism and Exposure Across Populations—Implication for Drug Safety, Dosing, and Individualized Therapy2021 Frontiers in Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Immaculate Mbongo Langmia, Katja Susanne Just, Sabrina Yamoune, Jürgen Brockmöller, Collen Mutowembwa Masimirembwa, Julia Stingl
95citations -
The impact of CYP2C19 genotype on phenoconversion by concomitant medication2023 Frontiers in Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Laura M. de Jong, Soukayna Boussallami, Martin A. Giera, Maarten E. Tushuizen, Menno Hoekstra, Lukas J.A.C. Hawinkels, +3 more
31citations -
Nutrimetric Validation of Solanidine as Dietary‐Derived CYP2D6 Activity Marker In Vivo2023 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Julian Peter Müller, Jens Andreas Sarömba, Patrick Ziegler, Roman Tremmel, Jens Rengelshausen, Elke Schaeffeler, +4 more
15citations -
Precision Treatment of Patients With GI Cancer Using Pre-emptive DPYD Genotyping/Phenotyping Plus Pharmacokinetic-Guided Dosing of 5-Fluorouracil2025 JCO Precision Oncology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Helle-Brit Fiebrich-Westra, Christina Haroun, Daphne den Besten-Bertholee, Maarten J. Deenen, Dirk Jan A. R. Moes, Pierre M. Bet, +4 more
11citations -
Design characteristics of mass balance studies conducted for protein kinase inhibitors2026 Cancer Chemotherapy and Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Benthe Riechelman, Ramon Bolks, Thijs H. Oude Munnink, Jesse Joachim Swen, Frank G. A. Jansman, Frank Klont
0citations -
Editorial: Innovations in pharmacogenomics: embracing diversity and clinical application2026 Frontiers in Pharmacology editorial Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Maaike van der Lee, Sarah Cargnin, Elena Peruzzi, Claudia Pisanu, Rossana Roncato
0citations -
DPYD c.85 T > C, DPYD c.496 A>G, and DPYD c.2194 G>A and severe toxicity to fluoropyrimidines in PREPARE and Alpe-DPD trials. An original study and meta-analysis2026 Pharmacological Research article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Elena De Mattia, Jerry Polesel, Maaike van der Lee, Stefan Böhringer, Martina Gambron, Samantha Perfler, +12 more
0citations