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Dravet variant SCN1A A1783V impairs interneuron firing predominantly by altered channel activation2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Nikolas Layer, Lukas Sonnenberg, Emilio Pardo González, Jan Benda, Holger Lerche, Henner Koch, +1 more
0citations -
The Concise Guide to PHARMACOLOGY 2023/24: Ion channels2023 British Journal of Pharmacology article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
S P H Alexander, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jörg Striessnig, Eamonn Kelly, +64 more
198citations -
High-throughput electrophysiology reveals subtype specific temperature dependence of sodium channel activation and inactivation2022 Biophysical Journal article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Sophia Kriegeskorte, Raya Bott, Ralf Hausmann, Angelika Lampert
1citations -
Loss-of-function variants in the KCNQ5 gene are associated with genetic generalized epilepsies2021 medRxiv preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Johanna Krüger, Julian Schubert, Josua Kegele, Audrey Labalme, Miaomiao Mao, Jacqueline Heighway, +15 more
3citations -
Gain-of-function mutation in SCN11A causes itch and affects neurogenic inflammation and muscle function in Scn11a+/L799P mice2020 PLoS ONE article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Matthias Ebbinghaus, Lorena P. N. Tuchscherr, Gisela Segond von Banchet, Lutz Liebmann, Volker Adams, Mieczyslaw R. Gajda, +3 more
16citations -
Uncoupling sodium channel dimers restores the phenotype of a pain‐linked Na v 1.7 channel mutation2020 British Journal of Pharmacology article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Annika H. Rühlmann, Jannis Körner, Ralf Hausmann, Nikolay Bebrivenski, Christian Neuhof, Silvia Detro‐Dassen, +6 more
29citations -
Protein semisynthesis underscores role of a conserved lysine in activation and desensitization of acid-sensing ion channels2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Ion Channels and Receptors Open access
Debayan Sarkar, Iacopo Galleano, Stephanie Andrea Heusser, Sofie Yuewei Ou, Gül Refika Uzun, Keith K. Khoo, +3 more
1citations -
Electrophysiological characterization of schizophrenia-associated variants in NaV1.2 sodium channel2022 European Psychiatry article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
M. Suslova, Petra A. I. Hautvast, Arnim Johannes Gaebler, Angelika Lampert
0citations -
Protein semi-synthesis enables real-time optical tracking of intracellular conformational changes during sodium channel inactivation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Laurie Peverini, Michelle Nilsson, Iacopo Galleano, Vita Sereika-Bejder, Emma Krindel Beyer, Lukas Fagerlund, +4 more
0citations -
A conserved peptide-binding pocket in HyNaC/ASIC ion channels2024 Proceedings of the National Academy of Sciences article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Audrey Ortega-Ramírez, Simone Albani, Michèle Bachmann, Axel Schmidt, Manuela Pinoé-Schmidt, Marc Assmann, +3 more
7citations -
Dravet Variant SCN1AA1783V Impairs Interneuron Firing Predominantly by Altered Channel Activation2021 Frontiers in Cellular Neuroscience article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Nikolas Layer, Lukas Sonnenberg, Emilio Pardo González, Jan Benda, Ulrike B. S. Hedrich, Holger Lerche, +2 more
17citations -
Dataset of electrophysiological patch-clamp recordings of the effect of the compounds deltamethrin, ATx-II and β4-peptide on human cardiac Nav1.5 sodium channel gating properties2020 Data in Brief data-paper Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Sarah Thull, Cristian Neacsu, Andrias O. O’Reilly, Stefanie Bothe, Ralf Hausmann, Tobias Huth, +2 more
6citations -
Phosphorylation of a chronic pain mutation in the voltage-gated sodium channel Nav1.7 increases voltage sensitivity2020 Journal of Biological Chemistry article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Clara M. Kerth, Petra A. I. Hautvast, Jannis Körner, Angelika Lampert, Jannis Meents
18citations -
The Effects of Repetitive Use and Pathological Remodeling on Channelrhodopsin Function in Cardiomyocytes2021 Frontiers in Physiology article Neuroscience Photoreceptor and optogenetics research Open access
Balázs Ördög, Alexander S Teplenin, Tim De Coster, Cindy I. Bart, Sven O. Dekker, Juan Zhang, +3 more
9citations -
Functional analysis in a model sea anemone reveals phylogenetic complexity and a role in cnidocyte discharge of DEG/ENaC ion channels2023 Communications Biology article Earth and Planetary Sciences Marine Invertebrate Physiology and Ecology Open access
José María Aguilar-Camacho, Katharina Foreman, Adrian Jaimes‐Becerra, Reuven Aharoni, Stefan Gründer, Yehu Moran
26citations -
Targeting the Kv11.1 (hERG) channel with allosteric modulators. Synthesis and biological evaluation of three novel series of LUF7346 derivatives2020 European Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Jacobus P. D. van Veldhoven, Giulia Campostrini, Constantijn J.E. van Gessel, Dorien Ward‐van Oostwaard, Rongfang Liu, Christine L. Mummery, +2 more
7citations -
Cold and warmth intensify pain-linked sodium channel gating effects and persistent currents2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Sophia Kriegeskorte, Raya Bott, Alon Korngreen, Ralf Hausmann, Angelika Lampert
0citations