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Development of a Versatile Cancer Vaccine Format Targeting Antigen-Presenting Cells Using Proximity-Based Sortase A-Mediated Ligation of T-Cell Epitopes2024 Bioconjugate Chemistry article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Aru Z. Wang, Hendrik J. Brink, Rianne G. Bouma, Alsya J. Affandi, Maarten K. Nijen Twilhaar, D.A.M. Heijnen, +13 more
4citations -
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2 specific CD8 T cell responses following COVID-192021 Zenodo (CERN European Organization for Nuclear Research) article Medicine SARS-CoV-2 and COVID-19 Research Open access
Anna H.E. Roukens, Cilia R. Pothast, Marion Koning, Wesley Huisman, Renate S. Hagedoorn, Mihaela Zlei, +10 more
2citations -
Strand-specific single-cell methylomics reveals distinct modes of DNA demethylation dynamics during early mammalian development2021 Nature Communications article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Maya Sen, Dylan Mooijman, Alex Chialastri, Jean-Charles Boisset, Mina Popovic, Björn Heindryckx, +3 more
30citations -
Association Between the Magnitude of Intravenous Busulfan Exposure and Development of Hepatic Veno-Occlusive Disease in Children and Young Adults Undergoing Myeloablative Allogeneic Hematopoietic Cell Transplantation39citations
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ECM-transmitted shear stress induces apoptotic cell extrusion in early breast gland development2022 Frontiers in Cell and Developmental Biology article Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Florian Friedland, Srivalliputtur Sarath Babu, Ronald Springer, Yannick Herfs, J. Gehlen, H.-J. Krause, +3 more
9citations -
Preclinical Development of Autologous Hematopoietic Stem Cell-Based Gene Therapy for Immune Deficiencies: A Journey from Mouse Cage to Bed Side2020 Pharmaceutics article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Laura García-Pérez, Anita Ordas, Kirsten Canté-Barrett, Pauline Meij, Karin Pike‐Overzet, Arjan C. Lankester, +1 more
10citations -
Development of a high-throughput in vitro screening method for the assessment of cell-damaging activities of snake venoms2023 PLoS neglected tropical diseases article Biochemistry, Genetics and Molecular Biology Venomous Animal Envenomation and Studies Open access
Mátyás A. Bittenbinder, Liliana Capinha, Daniel Da Costa Pereira, Julien Slagboom, Bas van de Velde, Nicholas R. Casewell, +3 more
11citations -
Quantitative modeling of tumor dynamics and development of drug resistance in non‐small cell lung cancer patients treated with erlotinib2024 CPT Pharmacometrics & Systems Pharmacology article Medicine Lung Cancer Treatments and Mutations Open access
Anyue Yin, G. Veerman, J. G. Coen van Hasselt, Christi M. J. Steendam, Hendrikus Jan Dubbink, Henk‐Jan Guchelaar, +4 more
6citations -
Development and Portability of a Text Mining Algorithm for Capturing Disease Progression in Electronic Health Records of Patients With Stage IV Non–Small Cell Lung Cancer2024 JCO Clinical Cancer Informatics article Computer Science Machine Learning in Healthcare Open access
Marjon V. Verschueren, Hanieh Abedian Kalkhoran, Maarten J. Deenen, Ben E.E.M. van den Borne, J. Zwaveling, Loes E. Visser, +3 more
2citations -
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development2021 Atherosclerosis article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Ana Quiles‐Jiménez, Ida Gregersen, Filip M. Segers, Tonje Skarpengland, Penelope Kroustallaki, Kuan Yang, +24 more
19citations -
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-192021 Nature Immunology article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 4 patents
Anna H.E. Roukens, Cilia R. Pothast, Marion H. König, Wesley Huisman, Tim J. Dalebout, Tamar Tak, +71 more
129citations -
Development of DuoMYC: a synthetic cell penetrant miniprotein that efficiently inhibits the oncogenic transcription factor MYC2024 Angewandte Chemie International Edition article Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Brecht D. Ellenbroek, Jan Pascal Kahler, Damiano Arella, Cherina Lin, Willem Jespers, Eliane Ann-Katrin Züger, +2 more
10citations -
Development of DuoMYC: a synthetic cell penetrant miniprotein that efficiently inhibits the oncogenic transcription factor MYC2024 Angewandte Chemie article Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Brecht D. Ellenbroek, Jan Pascal Kahler, Damiano Arella, Cherina Lin, Willem Jespers, Eliane Ann-Katrin Züger, +2 more
0citations -
Development and validation of a supervised deep learning algorithm for automated whole‐slide programmed death‐ligand 1 tumour proportion score assessment in non‐small cell lung cancer
Liesbeth M. Hondelink, Melek Hüyük, Pieter E. Postmus, Vincent T.H.B.M. Smit, Sami Blom, Jan H. von der Thüsen, +1 more
49citations -
Endogenous auxin maintains embryonic cell identity and promotes somatic embryo development in Arabidopsis2022 The Plant Journal article Agricultural and Biological Sciences Plant Molecular Biology Research Open access
Cheryl Philipsen, Arezoo Rahimi, Annisa Ratna Nurillah, Kim Boutilier, Remko Offringa
60citations -
Retinoic acid‐loaded liposomes induce human mucosal CD103 + dendritic cells that inhibit Th17 cells and drive regulatory T‐cell development in vitro2024 European Journal of Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Noémi Anna Nagy, Florianne Hafkamp, Rinske Sparrius, Rico Bas, Fernando Lozano Vigario, Toni M.M. van Capel, +5 more
11citations -
Development and characterization of a robust in vitro disease cell line to study tauopathies2023 Alzheimer s & Dementia article Medicine Alzheimer's disease research and treatments Open access
Laila Ritsma, Malika Bsibsi, Ludovico Buti, Fleur Stevenhagen, Sara Compte-Sancerni, Esther de Kraa, +5 more
1citations