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Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes2020 BMC Bioinformatics article Biochemistry, Genetics and Molecular Biology Cell Image Analysis Techniques Open access
Lu Cao, Andries D. van der Meer, Fons J. Verbeek, Robert C. J. J. Passier
14citations -
Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities2026 Angewandte Chemie International Edition article Medicine Microbial Natural Products and Biosynthesis Open access
Rongbin Wang, Heli Tirkkonen, Sabina Y. van der Zanden, Larissa V. Ponomareva, Isaline Fagon, Leslie Fève, +10 more
0citations -
CYP2B6 Functional Variability in Drug Metabolism and Exposure Across Populations—Implication for Drug Safety, Dosing, and Individualized Therapy2021 Frontiers in Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Immaculate Mbongo Langmia, Katja Susanne Just, Sabrina Yamoune, Jürgen Brockmöller, Collen Mutowembwa Masimirembwa, Julia Stingl
95citations -
Primary therapy and relative survival in patients with lymphoplasmacytic lymphoma/Waldenström macroglobulinaemia: a population‐based study in the Netherlands, 1989–20182021 British Journal of Haematology article Medicine Chronic Lymphocytic Leukemia Research Open access
Karima Amaador, Marie José Kersten, Otto J. Visser, Mirian Brink, Eduardus F. M. Posthuma, Monique C. Minnema, +2 more
11citations -
The Extension of the LeiCNS-PK3.0 Model in Combination with the “Handshake” Approach to Understand Brain Tumor Pathophysiology2022 Pharmaceutical Research article Neuroscience Barrier Structure and Function Studies Open access
Makoto Hirasawa, Mohammed A. A. Saleh, Elizabeth C. M. de Lange
7citations -
Identification and comparison of sex‐specific serious adverse drug reactions in spontaneous reports and systematically collected reports (ADRED)2023 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacovigilance and Adverse Drug Reactions Open access
Patrick Christ, Diana Dubrall, Katja Susanne Just, Britta R. Lewke, Maike Below, Julia Stingl, +2 more
3citations -
Reducing administrative burden in cardio-oncology: an LLM-powered approach for automated summarization of oncology and cardiotoxicity histories in dutch medical records2025 European Heart Journal Supplements article Medicine Artificial Intelligence in Healthcare and Education Open access
Julius Cornelis Heemelaar, Meena Fatah, Cees J.J. Westermann, Marieke Meija van Buchem, J. Wouter Jukema, M. Louisa Antoni
1citations -
Discovery and Optimization of a Novel Series of Pyrazolopyrimidines as Spermine Oxidase Inhibitors2025 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Polyamine Metabolism and Applications
Josep Llaveria, Suraj Adhikary, Christophe Buyck, Santiago Cañellas, Jose Maria Cid, Ben Danna, +14 more
0citations -
Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity2020 Nature Communications article Medicine Chemotherapy-induced cardiotoxicity and mitigation Open access
J. G. Coen van Hasselt, Rayees Rahman, Jens Hansen, Alan D. Stern, Jaehee V. Shim, Yuguang Xiong, +10 more
52citations -
Cucurbitacin E and I target the JAK/STAT pathway and induce apoptosis in Sézary cells2020 Biochemistry and Biophysics Reports article Medicine Cutaneous lymphoproliferative disorders research Open access
Isabella J. Brouwer, Jacoba J. Out‐Luiting, Maarten H. Vermeer, Cornelis P. Tensen
14citations -
Solid-State Formation of a Potential Melphalan Delivery Nanosystem Based on β-Cyclodextrin and Silver Nanoparticles2023 International Journal of Molecular Sciences article Pharmacology, Toxicology and Pharmaceutics Drug Solubulity and Delivery Systems Open access
Rodrigo Sierpe, Orlando Donoso-González, Erika Lang, Michael Noyong, Ulrich Simon, Marcelo Javier Kogan, +1 more
14citations -
Piperazine squaric acid diamides, a novel class of allosteric P2X7 receptor antagonists2021 European Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling Open access
Marius Patberg, Andreas Isaak, Friederike T. Füsser, Natalia V. Ortiz Zacarı́as, Laura Vinnenberg, Janine Schulte, +8 more
14citations -
Microwave-Assisted Synthesis, Structure, and Preliminary Biological Evaluation of Novel 6-Methoxy-5,6-dihydro-5-azapurines2023 ACS Omega article Chemistry Synthesis and Characterization of Heterocyclic Compounds Open access
Alena I. Siutkina, Svetlana A. Kalinina, Rongfang Liu, Laura H. Heitman, Anna Junker, Constantin Gabriel Daniliuc, +1 more
7citations -
Synthesis, structure and in vitro biological properties of a new copper(II) complex with 4-{[3-(pyridin-2-yl)-1H-pyrazol-1-yl]methyl}benzoic acid2021 Acta Crystallographica Section C Structural Chemistry article Chemistry Crystal structures of chemical compounds
Xinhua Li, Mengyuan Niu, Ai Wang, Liping Lu, Ulli Englert, Sisi Feng, +2 more
3citations -
731P The impact of proton pump inhibitors on pazopanib exposure2020 Annals of Oncology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Stefanie D. Krens, Floor J.E. Lubberman, Frank G. A. Jansman, David Marinus Burger, Paul Hamberg, Walter L. Vervenne, +4 more
0citations -
ALK and ERBB2 Protein Inhibition is Involved in the Prevention of Lung Cancer Development by Vincamine2023 Anti-Cancer Agents in Medicinal Chemistry article Computer Science Computational Drug Discovery Methods
Aarti Verma, Poonam Yadav, Sonu Rajput, Saloni Verma, Sahil Arora, Raj Kumar, +3 more
5citations -
Identification of acetylshikonin as a novel tubulin polymerization inhibitor with antitumor activity in human hepatocellular carcinoma cells2023 Journal of Gastrointestinal Oncology article Biochemistry, Genetics and Molecular Biology Microtubule and mitosis dynamics Open access
Yongchuan Li, Junqiu Zhou, Kun Xu, Yanqing Pang, Ralf Weiskirchen, Matthias Ocker, +1 more
2citations