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Linalool in cancer pharmacology: pharmacokinetic limitations and preclinical cytotoxic evidence for translational development2026 Frontiers in Pharmacology article Agricultural and Biological Sciences Essential Oils and Antimicrobial Activity Open access
Asad Abbas, Fatima Jafar, Ralf Weiskirchen, Adnan Amjad, Muhammad Khurram Afzal, Sawaira Bibi, +4 more
0citations -
Healthy volunteers in first‐in‐human oncology drug development for small molecules2021 British Journal of Clinical Pharmacology article Mathematics Statistical Methods in Clinical Trials Open access
Begoña de las Heras, Dalila Bouyoucef‐Cherchalli, Lesley Reeve, Andreas Reichl, Debra Mandarino, Stephen D. Flach, +3 more
18citations -
Severe drug-associated anaphylaxis: a complementary descriptive analyses of registry cases and spontaneous reports2025 European Journal of Clinical Pharmacology article Medicine Drug-Induced Adverse Reactions Open access
Patrick Christ, Diana Dubrall, Sabine Dölle-Bierke, Wojciech Francuzik, Matthias C. Schmid, Bernhardt Sachs, +1 more
4citations -
Biotin-decorated all-HPMA polymeric micelles for paclitaxel delivery2020 Journal of Controlled Release article Materials Science Nanoparticle-Based Drug Delivery Open access
Yan Wang, Mies J. van Steenbergen, Nataliia Beztsinna, Yang Mei Shi, Twan Lammers, Cornelus F. van Nostrum, +1 more
67citations -
Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes2020 BMC Bioinformatics article Biochemistry, Genetics and Molecular Biology Cell Image Analysis Techniques Open access
Lu Cao, Andries D. van der Meer, Fons J. Verbeek, Robert C. J. J. Passier
14citations -
Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities2026 Angewandte Chemie International Edition article Medicine Microbial Natural Products and Biosynthesis Open access
Rongbin Wang, Heli Tirkkonen, Sabina Y. van der Zanden, Larissa V. Ponomareva, Isaline Fagon, Leslie Fève, +10 more
0citations -
CYP2B6 Functional Variability in Drug Metabolism and Exposure Across Populations—Implication for Drug Safety, Dosing, and Individualized Therapy2021 Frontiers in Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Immaculate Mbongo Langmia, Katja Susanne Just, Sabrina Yamoune, Jürgen Brockmöller, Collen Mutowembwa Masimirembwa, Julia Stingl
95citations -
Primary therapy and relative survival in patients with lymphoplasmacytic lymphoma/Waldenström macroglobulinaemia: a population‐based study in the Netherlands, 1989–20182021 British Journal of Haematology article Medicine Chronic Lymphocytic Leukemia Research Open access
Karima Amaador, Marie José Kersten, Otto J. Visser, Mirian Brink, Eduardus F. M. Posthuma, Monique C. Minnema, +2 more
11citations -
The Extension of the LeiCNS-PK3.0 Model in Combination with the “Handshake” Approach to Understand Brain Tumor Pathophysiology2022 Pharmaceutical Research article Neuroscience Barrier Structure and Function Studies Open access
Makoto Hirasawa, Mohammed A. A. Saleh, Elizabeth C. M. de Lange
7citations -
Identification and comparison of sex‐specific serious adverse drug reactions in spontaneous reports and systematically collected reports (ADRED)2023 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacovigilance and Adverse Drug Reactions Open access
Patrick Christ, Diana Dubrall, Katja Susanne Just, Britta R. Lewke, Maike Below, Julia Stingl, +2 more
3citations -
Reducing administrative burden in cardio-oncology: an LLM-powered approach for automated summarization of oncology and cardiotoxicity histories in dutch medical records2025 European Heart Journal Supplements article Medicine Artificial Intelligence in Healthcare and Education Open access
Julius Cornelis Heemelaar, Meena Fatah, Cees J.J. Westermann, Marieke Meija van Buchem, J. Wouter Jukema, M. Louisa Antoni
1citations -
DNA Damage Independent Inhibition of NF-κB Transcription by Anthracyclines2021 SSRN Electronic Journal preprint Biochemistry, Genetics and Molecular Biology NF-κB Signaling Pathways Open access
Ângelo Ferreira Chora, Dora C. S. Pedroso, Eleni Kyriakou, Nadja Pejanovic, Henrique G. Colaço, Raffaella Gozzelino, +20 more
0citations -
Abstract 464: Allicin, a potent new ornithine decarboxylase inhibitor in neuroblastoma2020 Cancer Research conference-abstract Biochemistry, Genetics and Molecular Biology Polyamine Metabolism and Applications
Chad R. Schultz, Martin C. H. Gruhlke, Alan John Slusarenko, André S. Bachmann
0citations -
Discovery and Optimization of a Novel Series of Pyrazolopyrimidines as Spermine Oxidase Inhibitors2025 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Polyamine Metabolism and Applications
Josep Llaveria, Suraj Adhikary, Christophe Buyck, Santiago Cañellas, Jose Maria Cid, Ben Danna, +14 more
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Natural products in drug discovery: advances and opportunities2021 Nature Reviews Drug Discovery review Medicine Microbial Natural Products and Biosynthesis Open access cited by 8 patents
Atanas G. Atanasov, Sergey B. Zotchev, Verena Maria Dirsch, İlkay Erdoğan Orhan, Maciej Banach, Judith Maria Rollinger, +66 more
5,478citations -
Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity2020 Nature Communications article Medicine Chemotherapy-induced cardiotoxicity and mitigation Open access
J. G. Coen van Hasselt, Rayees Rahman, Jens Hansen, Alan D. Stern, Jaehee V. Shim, Yuguang Xiong, +10 more
52citations -
Piperazine squaric acid diamides, a novel class of allosteric P2X7 receptor antagonists2021 European Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling Open access
Marius Patberg, Andreas Isaak, Friederike T. Füsser, Natalia V. Ortiz Zacarı́as, Laura Vinnenberg, Janine Schulte, +8 more
14citations