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Axin2/Conductin Is Required for Normal Haematopoiesis and T Lymphopoiesis2022 Cells article Biochemistry, Genetics and Molecular Biology Wnt/β-catenin signaling in development and cancer Open access
Jolanda J. D. de Roo, Amiet R. Chhatta, Laura García-Pérez, Brigitta A. E. Naber, Sandra A. Vloemans, Daniela C. F. Salvatori, +3 more
5citations -
Mutational scanning reveals oncogenic CTNNB1 mutations have diverse effects on signaling2026 Nature Genetics article Biochemistry, Genetics and Molecular Biology Wnt/β-catenin signaling in development and cancer Open access
Anagha Krishna, Alison M. Meynert, Karamjit Singh Dolt, Martijn J. E. Kelder, Agavni Mesropian, Ailith Ewing, +21 more
13citations -
Cigarette smoke restricts the ability of mesenchymal cells to support lung epithelial organoid formation2023 Frontiers in Cell and Developmental Biology article Medicine Chronic Obstructive Pulmonary Disease (COPD) Research Open access
Padmini P. S. J. Khedoe, W. A. A. M. van Schadewijk, Max Schwiening, J. P. Ng-Blichfeldt, Stefan John Marciniak, Jan N Stolk, +2 more
14citations -
Lrp5 Mutant and Crispant Zebrafish Faithfully Model Human Osteoporosis, Establishing the Zebrafish as a Platform for CRISPR-Based Functional Screening of Osteoporosis Candidate Genes2020 Journal of Bone and Mineral Research article Biochemistry, Genetics and Molecular Biology Zebrafish Biomedical Research Applications Open access
Jan Willem Bek, Chen Shochat, Adelbert De Clercq, Hanna De Saffel, Annekatrien Boel, Juriaan R. Metz, +4 more
44citations -
Lrp5 mutant and crispant zebrafish faithfully model human osteoporosis, establishing the zebrafish as a platform for CRISPR-based functional screening of osteoporosis candidate genes2021 Bone Reports article Biochemistry, Genetics and Molecular Biology Zebrafish Biomedical Research Applications Open access
Jan Willem Bek, Chen Shochat, Adelbert De Clercq, Hanna De Saffel, Annekatrien Boel, Juriaan R. Metz, +4 more
4citations -
A Mosaic Variant in CTNNB1/β-catenin as a Novel Cause for Osteopathia Striata With Cranial Sclerosis2024 The Journal of Clinical Endocrinology & Metabolism article Biochemistry, Genetics and Molecular Biology Dermatological and Skeletal Disorders Open access
Yentl Huybrechts, Natasha M. Appelman‐Dijkstra, Ellen Steenackers, Wouter Van Beylen, Geert R. Mortier, Gretl Hendrickx, +1 more
3citations -
Identification of Compound Heterozygous Variants in LRP4 Demonstrates That a Pathogenic Variant outside the Third β-Propeller Domain Can Cause Sclerosteosis2021 Genes article Biochemistry, Genetics and Molecular Biology Dermatological and Skeletal Disorders Open access
Yentl Huybrechts, Eveline Boudin, Gretl Hendrickx, Ellen Steenackers, Neveen A. T. Hamdy, Geert R. Mortier, +4 more
9citations -
Histone lactylation-driven feedback loop modulates pyrimidine metabolism to promote oral carcinogenesis2026 Cell Death and Disease article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Yanting Wang, Yanlin Geng, Yannan Chen, Haowen Zhang, Jingyu Liu, Yulin Song, +3 more
5citations -
Pulmonary Microvascular Endothelial Cells Support Alveolar Epithelial Growth via Bone Morphogenetic Protein 6 Secretion2025 American Journal of Respiratory Cell and Molecular Biology article Medicine Neonatal Respiratory Health Research Open access
Luke van der Koog, Dyan F. Nugraha, Abilash Ravi, Justina Clarinda Wolters, Peter L. Horvatovich, Ken R. Bracke, +6 more
5citations -
The genetic architecture of the human cerebral cortex2020 Science article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Katrina L. Grasby, Neda Jahanshad, Jodie N. Painter, Lucía Colodro‐Conde, Janita Bralten, Derrek Paul Hibar, +93 more
863citations -
Oncogenic states dictate the prognostic and predictive connotations of intratumoral immune response2020 Journal for ImmunoTherapy of Cancer article Medicine Cancer Immunotherapy and Biomarkers Open access
Jessica P Roelands, Wouter Hendrickx, Gabriele M. Zoppoli, Raghvendra Mall, Mohamad Saad, Kyle D. Halliwill, +17 more
109citations -
Identical twins carry a persistent epigenetic signature of early genome programming2021 Nature Communications article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Jenny van Dongen, Scott D. Gordon, Allan F. McRae, Veronika V. Odintsova, Hamdi Mbarek, Charles E. Breeze, +29 more
63citations -
In vitro modelling of alveolar repair at the air-liquid interface using alveolar epithelial cells derived from human induced pluripotent stem cells2020 Scientific Reports article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 2 patents
Sander van Riet, Dennis K. Ninaber, Harald M. M. Mikkers, Teresa D. Tetley, Carolina R. Jost, Aat A. Mulder, +8 more
55citations -
Comparative genomic profiling of glandular bladder tumours2020 Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin article Medicine Urinary and Genital Oncology Studies Open access
Angela Maurer, Nadina Ortiz-Bruechle, Karolína Guricová, Michael Rose, Ronja Morsch, Stefan Garczyk, +12 more
44citations -
The Role of Small Molecules and Their Effect on the Molecular Mechanisms of Early Retinal Organoid Development2021 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access cited by 2 patents
Ellie L. Wagstaff, Andrea Heredero Berzal, Camiel J. F. Boon, Peter M. J. Quinn, Anneloor L.M.A. ten Asbroek, Arthur A B Bergen
42citations -
Single-Cell Transcriptomics Analysis of Human Small Antral Follicles2021 International Journal of Molecular Sciences article Medicine Reproductive Biology and Fertility Open access
Xueying Fan, Ioannis Moustakas, Monika Bialecka, Julieta S. del Valle, Arend W. Overeem, Leoni A. Louwé, +4 more
35citations -
A gastruloid model of the interaction between embryonic and extra-embryonic cell types2022 Journal of Tissue Engineering article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Noémie M. L. P. Bérenger-Currias, Maria Mircea, Esmée Adegeest, Patrick R. van den Berg, Marleen Feliksik, Mazène Hochane, +3 more
26citations -
Ligand–Receptor Interactions Elucidate Sex-Specific Pathways in the Trajectory From Primordial Germ Cells to Gonia During Human Development2021 Frontiers in Cell and Developmental Biology article Biochemistry, Genetics and Molecular Biology Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities Open access cited by 1 patent
Arend W. Overeem, Yolanda W. Chang, Jeroen Spruit, Celine M. Roelse, Susana M. Chuva de Sousa Lopes
23citations