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DNA nanostructure-templated antibody complexes provide insights into the geometric requirements of human complement cascade activation2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Complement system in diseases Open access
Leoni Abendstein, Willem E. M. Noteborn, Luc S. Veenman, Douwe J. Dijkstra, Fleur S. van de Bovenkamp, Leendert Adrianus Trouw, +1 more
0citations -
Long-term effects of combined B-cell immunomodulation with rituximab and belimumab in severe, refractory systemic lupus erythematosus: 2-year results2020 Nephrology Dialysis Transplantation article Medicine Systemic Lupus Erythematosus Research Open access
Tineke Kraaij, Eline J. Arends, Laura S. van Dam, Sylvia W.A. Kamerling, Paul L. A. van Daele, Obbo W Bredewold, +7 more
90citations -
Logic-gated antibody pairs that selectively act on cells co-expressing two antigens2022 Nature Biotechnology article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 7 patents
Simone C. Oostindie, Derek A. Rinaldi, Gijs G. Zom, Michael J. Wester, Desiree Paulet, Kusai Al-Tamimi, +14 more
49citations -
PTX3 structure determination using a hybrid cryoelectron microscopy and AlphaFold approach offers insights into ligand binding and complement activation2022 Proceedings of the National Academy of Sciences article Immunology and Microbiology Biomarkers in Disease Mechanisms Open access
Dylan P. Noone, Douwe J. Dijkstra, Teun T. van der Klugt, Peter A. van Veelen, Arnoud H. de Ru, Paul J. Hensbergen, +2 more
45citations -
The role of complement activation in autoimmune liver disease2020 Autoimmunity Reviews article Medicine Liver Diseases and Immunity Open access cited by 1 patent
Maaike Biewenga, Arantza Fariña Sarasqueta, Maarten E. Tushuizen, Eveline S. M. de Jonge‐Muller, Bart van Hoek, Leendert Adrianus Trouw
35citations -
Killer to cure: Expression and production costs calculation of tobacco plant‐made cancer‐immune checkpoint inhibitors2023 Plant Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access
Laura A. Ridgley, Nicole Falci Finardi, Benjamin Bruno Gengenbach, Patrick Opdensteinen, Zack Croxford, Julian K‐C., +3 more
28citations -
Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein19citations
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Non-professional efferocytosis of Salmonella -infected intestinal epithelial cells in the neonatal host2024 The Journal of Experimental Medicine article Immunology and Microbiology Phagocytosis and Immune Regulation Open access
Kaiyi Zhang, Urška Repnik, Nour Diab, Daniel Friske, Narasimha Murthy Keshava Prasad Gubbi, Michael Hensel, +4 more
17citations -
P127 Long-term effects of combined B-cell immunomodulation with rituximab and belimumab in severe, refractory SLE: two year results rituximab and belimumab combination for severe SLE2020 Poster presentations conference-abstract Medicine Systemic Lupus Erythematosus Research Open access
Tineke Kraaij, Eline J. Arends, Laura S. van Dam, Sylvia W.A. Kamerling, Paul L. A. van Daele, Obbo W Bredewold, +7 more
3citations -
Successful pharmacological intervention at different levels of the complement system in an in vitro complement fixation model for bullous pemphigoid
Jenny Giang, Martijn B. A. van Doorn, Gilles F.H. Diercks, Santiago Rodrı́guez de Córdoba, Thierry P. P. van den Bosch, Marco W.J. Schreurs, +2 more
3citations -
Classical Monocyte-Derived and Lipid-Associated TREM2+ Macrophages Orchestrate Inflammatory and Fibrotic Processes in ANCA-Associated Glomerulonephritis2023 Journal of the American Society of Nephrology conference-abstract Medicine Vasculitis and related conditions
Yosta Vegting, Aldo Jongejan, Annette E. Neele, Nike Claessen, Jesper Kers, Joris J. T. H. Roelofs, +7 more
0citations -
Lectin and alternative complement pathway activation in cutaneous manifestations of IgA-vasculitis: A new target for therapy?2022 Molecular Immunology article Immunology and Microbiology Complement system in diseases Open access
Jeffrey J. Damman, Antien L. Mooyaart, Thierry P. P. van den Bosch, Marc A. Seelen, Martijn B. van Doorn
20citations -
Enhancing complement activation by therapeutic anti-tumor antibodies: Mechanisms, strategies, and engineering approaches2024 Seminars in Immunology article Immunology and Microbiology Complement system in diseases Open access
Vitalijs Ovcinnikovs, Karin Dijkman, Gijs G. Zom, Frank J M Beurskens, Leendert Adrianus Trouw
18citations -
Targeting transthyretin ‐ Mechanism‐based treatment approaches and future perspectives in hereditary amyloidosis2020 Journal of Neurochemistry article Biochemistry, Genetics and Molecular Biology Amyloidosis: Diagnosis, Treatment, Outcomes Open access cited by 1 patent
Maike Franziska Dohrn, Sandra Michaela Ihne-Schubert, Ute Hegenbart, Jessica Medina, Stephan L. Zuchner, Teresa Coelho, +1 more
39citations -
Placental Complement Activation in Fetal and Neonatal Alloimmune Thrombocytopenia: An Observational Study2021 International Journal of Molecular Sciences article Medicine Blood groups and transfusion Open access
Thijs W. de Vos, Dian Winkelhorst, Hans J. Baelde, Kyra L. Dijkstra, Rianne D. M. van Bergen, Lotte E. van der Meeren, +13 more
23citations -
Infiltrative classical monocyte-derived and SPP1 lipid-associated macrophages mediate inflammation and fibrosis in ANCA-associated glomerulonephritis2024 Nephrology Dialysis Transplantation article Medicine Vasculitis and related conditions Open access
Yosta Vegting, Aldo Jongejan, Annette E. Neele, Nike Claessen, Gal Sela, Koen H.M. Prange, +10 more
18citations -
Infiltrative classical monocyte-derived and SPP1 lipid-associated macrophages mediate inflammation and fibrosis in ANCA-associated glomerulonephritis2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Vasculitis and related conditions Open access
Yosta Vegting, Aldo Jongejan, Annette E. Neele, Nike Claessen, Gal Sela, Koen H.M. Prange, +10 more
2citations