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In utero barcoding of mouse mesoderm reveals the clonal architecture of organ mesenchyme2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access
Jingyan He, Johan Lorentz, Agustín A. Corbat, Sergey V. Isaev, Raphaël Mauron, Sandra de Haan, +16 more
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A Novel FNDC1-NAMPT-NAD axis is Implicated in Small and Large-vessel Arterial Disease and Drives Vascular Calcification2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Parathyroid Disorders and Treatments Open access
Sujin Lee, Yugene Y. Guo, Lova Prasadareddy Kajuluri, Kangsan Roh, Kuldeep Singh, Wanlin Jiang, +28 more
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Oncogenic Ras-Src-cortactin signaling rewires actin-generated forces to drive basement membrane rupture and initiate breast cancer invasion2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Eric Platz‐Baudin, Julian Eschenbruch, Yannick Herfs, Georg Dreissen, Ronald Wein, Emiel P. C. van der Vorst, +3 more
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Multimodal single-cell analysis uncovers transcription factor networks underlying T-cell aging2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Mina Shaigan, Deepika Puri, Giulia Fornero, René Krüger, Mara Steiger, Hannes Klump, +4 more
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Oncostatin M cytokine promotes breast cancer progression by remodelling the extracellular matrix and activating integrin signalling in cancer cells2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cell Adhesion Molecules Research Open access
Peio Azcoaga, Andrea Abaurrea, Uxue Alvarez-Huesa, Paula Duch, Angela M. Araujo, Joanna I. López-Velazco, +12 more
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Mixed acid fermentation products from Lachnospira eligens counteract myotube atrophy2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Sophie Lecop, Edwige Piron, Audrey M. Neyrinck, Axelle E. Loriot, Sarah A. Pötgens, Raphaël Helaers, +12 more
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Physiologically relevant Multi-Omics Flux Analysis Reveals Metabolic Mechanisms of drug-Induced Liver Toxicity2026 Research Square preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Zita I. T. A. Soons, Ahenk Zeynep Sayin, Lars M. Blank, Adrian B. Roth, Marco Oldiges, Henrik Cordes, +1 more
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Single-cell and spatial transcriptomics resolve airway obliteration in bronchiolitis obliterans syndrome2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Transplantation: Methods and Outcomes Open access
Jannik Ruwisch, Hande Yilmaz, Leonard Christian, Lavinia Neubert, Lena Maureen Leiber, Annalea Brüggemann, +29 more
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Melatonin nanoparticles inhibit mutant hematopoiesis & restore bone marrow architecture in myeloproliferative neoplasms2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Siddharth Gupta, Alessandro Motta, Sara Elsafy, Shiva Khorshid, Alessia Nucci, Vishrutha Sampath, +22 more
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A Framework for NGN1-Induced Sensory Neuron Differentiation for Disease Modelling and Drug Screening2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Anika Neureiter, Marlene Menke, Veronica Donde, Cedric Guenther, Lennart Mueller, Florian Kraft, +10 more
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PCA3 Responsive Molecular Imaging Enables Spatial Visualization of Prostate Cancer2026 Research Square preprint Biochemistry, Genetics and Molecular Biology Advanced biosensing and bioanalysis techniques Open access
Sven Gerlach, Thomas Frank Ermler, Krisztina Percze, Dirk Mayer, Jennifer Kranz, Radu Alexa, +16 more
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In vitro programming and pseudounipolarization of human iPSC-derived sensory neurons2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Pascal Röderer, Ana Catarina Costa, Martha Lürkens, Fiona Roll, Franziska Buck, Luzia Heidrich, +19 more
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Multimodal evidence for impaired glymphatic brain clearance as a mediator of “inflammaging” in schizophrenia – integrating insights from in vivo neuroimaging, omics, and post-mortem single nucleus-RNA-Seq data2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Cerebrospinal fluid and hydrocephalus Open access
Xiaolin Tan, Malte Simon, Daniel Rosebrock, Mariia M Firulyova, Doris Gruber-Schoffnegger, Marisa Fuerst, +7 more
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Towards biomarkers for outcomes after pancreatic ductal adenocarcinoma and ischemic stroke, with focus on (co-)morbidity and aging / cellular senescence (SASKit): protocol for a prospective cohort study
Larissa Henze, Uwe Walter, Hugo Murua Escobar, Christian Junghanß, Robert Jaster, Rüdiger Köhling, +9 more
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