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Elevated MPS1 converts the fibrous corona into a source of chromosomal instability in colon cancer2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microtubule and mitosis dynamics Open access
Ana Pinto-Teixeira, André Oliveira, Gonçalo Gouveia, Ana Sousa, Jessica P Roelands, Marco Grillo, +15 more
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Benchmarking Imputation Methods for Single-Cell RNA Sequencing Data Using Peripheral Blood Mononuclear Cells from Acute Myocardial Infarction Patients0citations
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AtlasOT - The Fused Unbalanced Gromov-Wasserstein for Multimodal Integration of Disease Atlases2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Kai Peng, Mayra L. Ruiz Tejada Segura, Barthélémy Caron, Christoph Kuppe, James Shiniti Nagai, Ivan G. Costa
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T-cell distribution in the dorsal root ganglion across species, sex, and age2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Pain Mechanisms and Treatments Open access
Jayden A. O'Brien, Nishka Kuttanna, Khadijah Mazhar, Marisol Mancilla Moreno, Asta Arendt-Tranholm, Joseph B. Lesnak, +12 more
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A global AOP network for genotoxicity to drive the integration of NAMs2025 preprint Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Emmanuel Demuynck, Tamara Vanhaecke, Anouck Thienpont, Davie Cappoen, Freddy Van Goethem, Levi M. T. Winkelman, +14 more
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The Human Pancreas Cell Atlas defines a healthy reference framework for disease contextualization and translational benchmarking2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics
Shrey Parikh, Daniel C. Strobl, Sara Jiménez, Julia Beckmann, Lucas Arnoldt, Eljas Roellin, +19 more
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Adaptive laboratory evolution rewires Pseudomonas putida for resource-efficient acetate assimilation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Nicolás Gurdo, Aparajitha Srinivasan, Tommaso Tagliani, Melanie Filbig, Nicolas T. Wirth, Josefin Johnsen, +13 more
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The Brugada syndrome associated gene WT1 impacts on SCN5A expression and cardiac conduction2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cardiac electrophysiology and arrhythmias Open access
E. Madelief Marsman, Joost Allard Offerhaus, Thomas Stervinou, Leander Beekman, Simona Casini, T J Streef, +11 more
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Multi-omics reveals global signaling rewiring and identifies Activin A-induced dysregulation of FOS/Activator Protein 1 as a novel target in Fibrodysplasia ossificans progressiva2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Heterotopic Ossification and Related Conditions Open access
Marius Wits, Nerea Gomez-Suarez, Alexandre Deber, Nicole Farfán, Fjodor T. Bekedam, Bharath K. Sampadi, +8 more
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Single-myofiber RNA-sequencing reveals myofiber-level transcriptomic heterogeneity and DUX4 activation in FSHD muscle biopsies2025 Research Square preprint Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Silvère M. van der Maarel, Anita van den Heuvel, Dongxu Zheng, Svetlana Pasteuning-Vuhman, Joke W. Boertje-van der Meulen, Emile de Meijer, +2 more
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Randomized HyperSteiner: A Stochastic Delaunay Triangulation Heuristic for the Hyperbolic Steiner Minimal Tree2025 UvA-DARE (University of Amsterdam) preprint Computer Science Computational Geometry and Mesh Generation Open access
Aniss Aiman Medbouhi, Alejandro García-Castellanos, Giovanni Luca Marchetti, Daniël M. Pelt, Erik J. Bekkers, Danica Kragić
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Interleukin-6 restricts pre-thymic T cell lineage commitment of progenitors driving loss of SIV control2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology HIV Research and Treatment Open access
Saleem Anwar, Naseem Sadek, Christian Michel Beusch, Ahmet F. Coskun, Mohamed S. Abdel-Hakeem, R. Paul Johnson, +8 more
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Morphoelectric Diversity and Specialization of Neuronal Cell Types in the Primate Striatum2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Xiao-Ping Liu, Rachel A. Dalley, Nelson Johansen, Agata Budzillo, Julian Thijssen, Jeremy A. Miller, +86 more
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Multi-omics characterization of breast cancer metabolism identifies new metabolic targets2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Hanneke Leegwater, Xiaobing Zhang, Luojiao Huang, Christine Hoegen, Xuesong Wang, Agnieszka B. Wegrzyn, +6 more
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Cell DiffErential Expression by Pooling (CellDEEP) highlights issues in differential gene expression in scRNA-seq2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Yiyi Cheng, Toby Kettlewell, Ross F Laidlaw, Olympia M Hardy, Andrew McCluskey, Thomas D. Otto, +1 more
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Loss of ABCA4 from photoreceptor discs triggers changes in glial cell homeostasis2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Rossella Valenzano, Andrew J. McDonald, Carmen Gallego, Charlotte A. Andriessen, Ioannis Moustakas, Aat A. Mulder, +4 more
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Context-dependent molecular responses to heterogeneous metabolic disease traits2026 medRxiv preprint Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Theodora-Dafni Michalettou, Sapna Sharma, Natalie N. Atabaki, Juan J. Fernandez-Tajes, Mun‐Gwan Hong, Jonathan Adam, +34 more
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Ageing of the Upper Airway Epithelial Niche Limits Tissue-Resident T Cell Immunity2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Wesley Huisman, Lisa A. King, Youvika Singh, Alicia C. de Kroon, Rosanne A. M. Steenbergen, Iris van der Valk, +20 more
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