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Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication2023 Cellular and Molecular Life Sciences article Medicine Mosquito-borne diseases and control Open access
Sarah Krieg, Fabian Pott, Laura Potthoff, Maud Verheirstraeten, Mareike Bütepage, Alexandra Golzmann, +4 more
39citations -
Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis2023 PLoS Pathogens article Agricultural and Biological Sciences Animal Virus Infections Studies Open access
Ben A. Bailey-Elkin, Robert C. M. Knaap, Anuradha De Silva, Ilse M. Boekhoud, Sandra TM Mous, Niek van Vught, +4 more
10citations -
Vaccines based on replication incompetent Ad26 viral vectors: Standardized template with key considerations for a risk/benefit assessment2020 Vaccine article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 2 patents
Jerome H. H. V. Custers, Denny Kim, Maarten Leyssen, Marc Gurwith, Frank L. Tomaka, James S. Robertson, +10 more
84citations -
6′-β-Fluoro-Homoaristeromycin and 6′-Fluoro-Homoneplanocin A Are Potent Inhibitors of Chikungunya Virus Replication through Their Direct Effect on Viral Nonstructural Protein 12020 Antimicrobial Agents and Chemotherapy article Medicine Mosquito-borne diseases and control Open access
Bas M. Morren, Ali Taş, Irina C. Albulescu, Robin van Rijswijk, Dnyandev B. Jarhad, Young Sup Shin, +6 more
35citations -
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology2020 Journal of General Virology article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 17 patents
Natacha S. Ogando, Tim J. Dalebout, Jessika C. Zevenhoven-Dobbe, Ronald W.A.L. Limpens, Leon Caly, Julian D Druce, +5 more
557citations -
Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies2023 PLoS Computational Biology article Medicine Mathematical and Theoretical Epidemiology and Ecology Models Open access
Carolin Zitzmann, Christopher Dächert, Bianca Schmid, Hilde M. van der Schaar, Martijn J. van Hemert, Alan S. Perelson, +4 more
14citations -
Conserved structural features of RNA export pores spanning the double membrane of arterivirus and coronavirus replication organelles2026 Journal of Virology article Agricultural and Biological Sciences Animal Virus Infections Studies Open access
Nina L. de Beijer, Ronald W.A.L. Limpens, Montserrat Bárcena, Eric J. Snijder
0citations -
Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo
Mariska van Huizen, Jonna R. Bloeme - ter Horst, Heidi L. M. De Gruyter, Paul P. Geurink, Gerbrand J. van der Heden van Noort, Robert C. M. Knaap, +8 more
23citations -
Glucocorticoids Do Not Enhance BK Polyomavirus Replication in Human Renal Proximal Tubular Epithelial Cells In Vitro2026 Clinical and Translational Science article Medicine Polyomavirus and related diseases Open access
Wouter T. Moest, Reshma A. Lalai, Jurriën Prins, Aiko P. J. de Vries, Els Wessels, Cees van Kooten, +2 more
0citations -
Macrophage-augmented intestinal organoids model virus-host interactions in enteric viral diseases and facilitate therapeutic development2025 Nature Communications article Medicine Viral gastroenteritis research and epidemiology Open access
Guige Xu, Yining Wang, Theano Tsikari, Qin Fang, Francijna E. van den Hil, Patrick P.C. Boor, +13 more
20citations -
Tomatidine reduces Chikungunya virus progeny release by controlling viral protein expression2021 PLoS neglected tropical diseases article Medicine Mosquito-borne diseases and control Open access
Berit Troost-Kind, Martijn J. van Hemert, Denise P.I. van de Pol, Heidi H. van der Ende-Metselaar, Andres Merits, Malte Borggrewe, +2 more
18citations -
Compounds derived from Humulus lupulus inhibit SARS-CoV-2 papain-like protease and virus replication2023 Phytomedicine article Pharmacology, Toxicology and Pharmaceutics Hops Chemistry and Applications Open access
Anna-Maria Herzog, Katharina Göbel, Luigi Marongiu, Natalia Ruétalo, Marta Campos Alonso, Christian Leischner, +8 more
14citations -
Acute cigarette smoke exposure leads to higher viral infection in human bronchial epithelial cultures by altering interferon, glycolysis and GDF15-related pathways2023 Respiratory Research article Medicine Chronic Obstructive Pulmonary Disease (COPD) Research Open access
Ying Wang, Dennis K. Ninaber, Alen Faiz, Abraham C. van der Linden, Annemarie M. van Schadewijk, René Lutter, +3 more
13citations -
Suramin Inhibits SARS-CoV-2 Infection in Cell Culture by Interfering with Early Steps of the Replication Cycle2020 Antimicrobial Agents and Chemotherapy article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 3 patents
Clarisse Salgado‐Benvindo, Melissa Thaler, Ali Taş, Natacha S. Ogando, Peter J. Bredenbeek, Dennis K. Ninaber, +4 more
112citations -
Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery2020 Antimicrobial Agents and Chemotherapy article Medicine Mosquito-borne diseases and control Open access
Rana Abdelnabi, Julia Moesslacher, Kim Donckers, Verena Battisti, Pieter Leyssen, Thierry Langer, +11 more
29citations -
Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation2020 PLoS Computational Biology article Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Simon Dirmeier, Christopher Dächert, Martijn J. van Hemert, Ali Taş, Natacha S. Ogando, Frank J. M. van Kuppeveld, +4 more
23citations -
Synthesis of a guanylylated peptide derived from norovirus VPg as a molecular tool for studying norovirus replication2026 RSC Chemical Biology article Medicine Viral gastroenteritis research and epidemiology Open access
Bob van Puffelen, Leandro Xavier Neves, Roy Steneker, Nico J. Meeuwenoord, Edward Emmott, Dmitri V. Filippov
0citations