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Utilizing protein structure graph embeddings to predict the pathogenicity of missense variants2025 NAR Genomics and Bioinformatics article Biochemistry, Genetics and Molecular Biology Genomics and Rare Diseases Open access
Martin Danner, Matthias Begemann, Miriam Elbracht, Ingo Kurth, Jeremias Krause
2citations -
Unsupervised protein embeddings outperform hand-crafted sequence and structure features at predicting molecular function2020 Bioinformatics article Biochemistry, Genetics and Molecular Biology Machine Learning in Bioinformatics Open access cited by 2 patents
Amelia Villegas-Morcillo, Stavros Makrodimitris, Roeland C. H. J. van Ham, Angel Manuel Gomez, Marcel J. T. Reinders
137citations -
Isotope Decluttering Reduces Spectral Complexity while Maintaining Protein Structure2026 Analytical Chemistry article Chemistry Mass Spectrometry Techniques and Applications Open access
Sneha Hakke, Willem E. M. Noteborn, Birol Cabukusta, Ye Gao, Kèvin Knoops, Carmen López‐Iglesias, +4 more
0citations -
The Crystal Structure of the Defense Conferring Rice Protein OsJAC1 Reveals a Carbohydrate Binding Site on the Dirigent-like Domain2022 Biomolecules article Agricultural and Biological Sciences Plant-Microbe Interactions and Immunity Open access
Nikolai Huwa, Oliver H. Weiergräber, Alexander Veljko Fejzagić, Christian Kirsch, Ulrich Schaffrath, Thomas Claßen
12citations -
Critical assessment of structure-based approaches to improve protein resistance in aqueous ionic liquids by enzyme-wide saturation mutagenesis2021 Computational and Structural Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access
Till El Harrar, Mehdi D. Davari, Karl‐Erich Jaeger, Ulrich Schwaneberg, Holger Gohlke
14citations -
Bone morphogenetic protein receptors: Structure, function and targeting by selective small molecule kinase inhibitors2020 Bone article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access cited by 13 patents
Gonzalo Sánchez‐Duffhues, Eleanor Williams, Marie‐José Goumans, Carl‐Henrik Heldin, Peter ten Dijke
118citations -
In Cellulo Cysteine Umpolung for Protein Structure Probing2025 Journal of the American Chemical Society article Chemistry Click Chemistry and Applications Open access
Philipp Hartmann, Kostiantyn Bohdan, Lara Vogelsang, Dario Marchionni, Christian Preisinger, Alessandro Vetere, +2 more
11citations -
Application of a novel RNA-protein interaction assay to develop inhibitors blocking RNA-binding of the HuR protein2025 Frontiers in Genetics article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Larissa Filcenkova, Annika Reisbitzer, Benjamin Philipp Joseph, Verena Weber, Paolo Carloni, Giulia Rossetti, +1 more
0citations -
ProteinCT: An implementation of the protein circuit topology framework2022 MethodsX article Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Duane Moes, Seyedeh Elnaz Banijamali, Vahid Sheikhhassani, Barbara Scalvini, Jaie C. Woodard, Alireza Mashaghi
7citations -
Structure, Functions, and Implications of Selected Lipocalins in Human Disease2024 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Protein Interaction Studies and Fluorescence Analysis Open access
Preethi Chandrasekaran, Sabine Weiskirchen, Ralf Weiskirchen
39citations -
PTX3 structure determination using a hybrid cryoelectron microscopy and AlphaFold approach offers insights into ligand binding and complement activation2022 Proceedings of the National Academy of Sciences article Immunology and Microbiology Biomarkers in Disease Mechanisms Open access
Dylan P. Noone, Douwe J. Dijkstra, Teun T. van der Klugt, Peter A. van Veelen, Arnoud H. de Ru, Paul J. Hensbergen, +2 more
45citations -
Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein19citations
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Transition between protein-like and polymer-like dynamic behavior: Internal friction in unfolded apomyoglobin depends on denaturing conditions2020 Scientific Reports article Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Livia Balacescu, Tobias E. Schrader, Aurel Rădulescu, Piotr A. Zolnierczuk, Olaf Holderer, Stefano Pasini, +2 more
14citations -
Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions2022 Proceedings of the National Academy of Sciences article Medicine Influenza Virus Research Studies Open access cited by 9 patents
Fin Milder, Mandy A. C. Jongeneelen, Tina Ritschel, Pascale Bouchier, Ilona J. M. Bisschop, Martijn de Man, +7 more
61citations