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Anti-tumor vaccine efficacy depends on adjuvant type and associates with induced IgG subclass and glycosylation profiles2025 Experimental Hematology and Oncology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Selina Lehrian, Anna Wasynczuk, Janina Petry, Melanie Guderian, Jan Nouta, Jana Sophia Buhre, +9 more
0citations -
IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming2020 The Journal of Immunology article Medicine Monoclonal and Polyclonal Antibodies Research Open access
Willianne Hoepel, Sona Allahverdiyeva, Haneen Harbiye, Steven W. de Taeye, Alwin J. van der Ham, Leonie de Boer, +7 more
21citations -
Definition of IgG Subclass-Specific Glycopatterns in Idiopathic Membranous Nephropathy: Aberrant IgG Glycoforms in Blood2022 International Journal of Molecular Sciences article Medicine Renal Diseases and Glomerulopathies Open access
Clizia Chinello, Noortje de Haan, Giulia Capitoli, Barbara Trezzi, Antonella Radice, Lisa Pagani, +6 more
20citations -
MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N-Glycosylation2020 Frontiers in Immunology article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Thomas Sénard, Andrea Gargano, David Falck, Steven W. de Taeye, Theo T. Rispens, Gestur Vidarsson, +3 more
294citations -
A robust nanoscale RP HPLC-MS approach for sensitive Fc proteoform profiling of IgG allotypes2023 Analytica Chimica Acta article Medicine Monoclonal and Polyclonal Antibodies Research Open access
Constantin Blöchl, Christoph Gstöttner, Thomas Sénard, Eva Maria Stork, Hans Ulrich Scherer, René E. M. Toes, +2 more
8citations -
FcγR Binding and ADCC Activity of Human IgG Allotypes2020 Frontiers in Immunology article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 9 patents
Steven W. de Taeye, Arthur E. H. Bentlage, Mirjam M. Mebius, Joyce I. Meesters, Suzanne N. Lissenberg‐Thunnissen, David Falck, +6 more
216citations -
Neutrophil Depletion Changes the N-Glycosylation Pattern of IgG in Experimental Murine Sepsis2024 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Kürşat Oğuz Yaykaşlı, Karin Anna van Schie, René E. M. Toes, Manfred Wuhrer, Carolien A. M. Koeleman, Galyna Bila, +5 more
7citations -
A functional spleen contributes to afucosylated IgG in humans2021 Scientific Reports article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Iwona Wójcik, David E. Schmidt, Lisa A. de Neef, Minke A.E. Rab, Bob Meek, Okke de Weerdt, +6 more
10citations -
C1q binding to surface-bound IgG is stabilized by C1r 2 s 2 proteases2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Complement system in diseases Open access
Seline A. Zwarthoff, Kevin Widmer, Annemarie Kuipers, Jürgen Strasser, Maartje Ruyken, Piet C. Aerts, +12 more
1citations -
Fc proteoforms of ACPA IgG discriminate autoimmune responses in plasma and synovial fluid of rheumatoid arthritis patients and associate with disease activity2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Rheumatoid Arthritis Research and Therapies Open access
Constantin Blöchl, Eva Maria Stork, Hans Ulrich Scherer, René E. M. Toes, Manfred Wuhrer, Elena Domínguez‐Vega
2citations -
Comprehensive overview of autoantibody isotype and subclass distribution2022 Journal of Allergy and Clinical Immunology article Medicine Systemic Lupus Erythematosus Research Open access
Mikhail Volkov, Mariateresa Coppola, Ruth Huizinga, Filip Eftimov, Tom W. J. Huizinga, Anneke J. van der Kooi, +10 more
56citations -
Differences in IgG autoantibody Fab glycosylation across autoimmune diseases2023 Journal of Allergy and Clinical Immunology article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Jana Koers, Rocco Sciarrillo, Ninotska I. L. Derksen, Esther M. Vletter, Yvonne E. Fillié‐Grijpma, Elisabeth Raveling‐Eelsing, +33 more
47citations -
Assessment of IgG‐Fc glycosylation from individual RhD‐specific B cell clones reveals regulation at clonal rather than clonotypic level2023 Immunology article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Erik L. de Graaf, Mads Delbo Larsen, Nieke van der Bolt, Remco Visser, Onno J. H. M. Verhagen, Agnes L. Hipgrave Ederveen, +4 more
3citations -
Direct measurement and reconstruction of intact polyclonal IgG repertoires to preserve molecular and functional connectivity2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Monoclonal and Polyclonal Antibodies Research Open access
Thomas Holmark, Despoina Mavridou, Ziran Zhai, Annika A. M. van der Zon, Constantin Blöchl, Elena Domínguez‐Vega, +1 more
0citations -
mRNA vaccines against SARS-CoV-2 induce comparably low long-term IgG Fc galactosylation and sialylation levels but increasing long-term IgG4 responses compared to an adenovirus-based vaccine
Jana Sophia Buhre, Tamás Pongrácz, Inga Künsting, Anne Sophie Lixenfeld, Wenjun Wang, Jan Nouta, +14 more
91citations -
IgG Fc sialylation is regulated during the germinal center reaction following immunization with different adjuvants2020 Journal of Allergy and Clinical Immunology article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Yannic C. Bartsch, Simon Eschweiler, Alexei Leliavski, Hanna B. Lunding, Sander Wagt, Janina Petry, +32 more
67citations