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Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains2023 Nature Communications article Immunology and Microbiology Complement system in diseases Open access cited by 2 patents
Leoni Abendstein, Douwe J. Dijkstra, Rayman T.N. Tjokrodirijo, Peter A. van Veelen, Leendert Adrianus Trouw, Paul J. Hensbergen, +1 more
50citations -
Simultaneous Immunoglobulin A and G Glycopeptide Profiling for High-Throughput Applications2020 Analytical Chemistry article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Ana Momčilović, Noortje de Haan, Agnes L. Hipgrave Ederveen, Albert Bondt, Carolien A. M. Koeleman, David Falck, +6 more
50citations -
Glycoform-resolved pharmacokinetic studies in a rat model employing glycoengineered variants of a therapeutic monoclonal antibody2020 mAbs article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 2 patents
David Falck, Marco Thomann, Martin Lechmann, Carolien A. M. Koeleman, Sebastian Malik, Cordula Jany, +2 more
42citations -
IFN-Stimulated Gene 15 Is an Alarmin that Boosts the CTL Response via an Innate, NK Cell–Dependent Route2020 The Journal of Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Victoria Iglesias‐Guimarais, Tomasz Ahrends, Evert de Vries, Klaus‐Peter Knobeloch, Andriy Volkov, Jannie G. Borst
38citations -
TEAD4 regulates trophectoderm differentiation upstream of CDX2 in a GATA3-independent manner in the human preimplantation embryo2022 Human Reproduction article Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access
Panagiotis Stamatiadis, Gwenny Cosemans, Annekatrien Boel, Björn Menten, Petra De Sutter, Dominic Stoop, +4 more
37citations -
Immunosuppression Has Long-Lasting Effects on Circulating Follicular Regulatory T Cells in Kidney Transplant Recipients2020 Frontiers in Immunology article Medicine Renal Transplantation Outcomes and Treatments Open access
Qian Niu, Aleixandra Mendoza Rojas, Dave L. Roelen, Marian C. Clahsen‐van Groningen, Lanlan Wang, Teun van Gelder, +3 more
29citations -
Killer to cure: Expression and production costs calculation of tobacco plant‐made cancer‐immune checkpoint inhibitors2023 Plant Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access
Laura A. Ridgley, Nicole Falci Finardi, Benjamin Bruno Gengenbach, Patrick Opdensteinen, Zack Croxford, Julian K‐C., +3 more
28citations -
Recognition of S100 proteins by Signal Inhibitory Receptor on Leukocytes‐1 negatively regulates human neutrophils2021 European Journal of Immunology article Biochemistry, Genetics and Molecular Biology S100 Proteins and Annexins Open access
Matevž Rumpret, Helen J. von Richthofen, Maarten van der Linden, Geertje H. A. Westerlaken, Cami M. P. Talavera Ormeño, Teck Yew Low, +2 more
28citations -
Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation2021 Cell Reports article Biochemistry, Genetics and Molecular Biology Microtubule and mitosis dynamics Open access
Stanislau Yatskevich, Jessie S. Kroonen, Claudio Alfieri, Thomas Tischer, Anna C. Howes, Linda Clijsters, +5 more
25citations -
Integrative dynamic structural biology unveils conformers essential for the oligomerization of a large GTPase2023 eLife article Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Thomas-Otavio Peulen, Carola S. Hengstenberg, Ralf Biehl, Mykola Dimura, Charlotte Lorenz, Alessandro Valeri, +9 more
24citations -
Safety, pharmacokinetics (PK), pharmacodynamics (PD) and preliminary efficacy of AZD2936, a bispecific antibody targeting PD-1 and TIGIT, in checkpoint inhibitor (CPI)-experienced advanced/metastatic non-small-cell lung cancer (NSCLC): First report of ARTEMIDE-01.2023 Journal of Clinical Oncology conference-abstract Medicine Cancer Immunotherapy and Biomarkers Open access
Kristoffer Staal Rohrberg, Mariana Brandão, Eduardo Castañón Álvarez, Enriqueta Felip, Eelke Hiddo Gort, T. Jeroen N. Hiltermann, +14 more
22citations -
TEIPP-vaccination in checkpoint-resistant non-small cell lung cancer: a first-in-human phase I/II dose-escalation study2025 Nature Communications article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Mitchell Emmers, Marij J.P. Welters, Michelle V. Dietz, Saskia J A M Santegoets, Sanne Boekesteijn, Anouk Stolk, +12 more
19citations -
Enhancing complement activation by therapeutic anti-tumor antibodies: Mechanisms, strategies, and engineering approaches2024 Seminars in Immunology article Immunology and Microbiology Complement system in diseases Open access
Vitalijs Ovcinnikovs, Karin Dijkman, Gijs G. Zom, Frank J M Beurskens, Leendert Adrianus Trouw
18citations -
Human anti-C1q autoantibodies bind specifically to solid-phase C1q and enhance phagocytosis but not complement activation2023 Proceedings of the National Academy of Sciences article Medicine Systemic Lupus Erythematosus Research Open access cited by 3 patents
Douwe J. Dijkstra, Fleur S. van de Bovenkamp, Leoni Abendstein, Rob Zuijderduijn, Jos Pool, Cynthia S. M. Kramer, +10 more
18citations -
Afucosylated broadly neutralizing antibodies enhance clearance of HIV-1 infected cells through cell-mediated killing2024 Communications Biology article Immunology and Microbiology HIV Research and Treatment Open access
Steven W. de Taeye, Angela I. Schriek, Jeffrey C. Umotoy, Marloes Grobben, Judith A. Burger, Rogier W. Sanders, +5 more
17citations -
YAP1 is essential for self-organized differentiation of pluripotent stem cells2023 Biomaterials Advances article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Kira Zeevaert, Roman Goetzke, Mohamed H. Elsafi Mabrouk, Catharina Maaßen, Ann-Christine Henneke, Chao He, +3 more
15citations