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The Extension of the LeiCNS-PK3.0 Model in Combination with the “Handshake” Approach to Understand Brain Tumor Pathophysiology2022 Pharmaceutical Research article Neuroscience Barrier Structure and Function Studies Open access
Makoto Hirasawa, Mohammed A. A. Saleh, Elizabeth C. M. de Lange
7citations -
Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice2023 Pharmaceutical Research article Neuroscience Barrier Structure and Function Studies Open access
Mohammed A. A. Saleh, Berfin Gülave, Olivia Campagne, Clinton F. Stewart, Jeroen Elassaiss‐Schaap, Elizabeth C. M. de Lange
5citations -
Sparser and Less Efficient Hippocampal-Prefrontal Projections account for Developmental Network Dysfunction in a Model of Psychiatric Risk Mediated by Gene-Environment Interaction2021 Journal of Neuroscience article Neuroscience Neuroscience and Neuropharmacology Research Open access
Lingzhen Song, Xiaxia Xu, Peggy Putthoff, David Fleck, Marc Spehr, Ileana L. Hanganu‐Opatz
14citations -
Sparser and Less Efficient Hippocampal-Prefrontal Projections account for Developmental Network Dysfunction in a Model of Psychiatric Risk Mediated by Gene-Environment Interaction2022 Zenodo (CERN European Organization for Nuclear Research) article Neuroscience Neuroscience and Neuropharmacology Research Open access
Lingzhen Song, Xiaxia Xu, Peggy Putthoff, David Spehr, Ileana L. Hanganu‐Opatz
0citations -
Exploring Kp,uu,BBB values smaller than unity in remoxipride: A physiologically-based CNS model approach highlighting brain metabolism in drugs with passive blood-brain barrier transport2024 European Journal of Pharmaceutical Sciences article Neuroscience Barrier Structure and Function Studies Open access
Mengxu Zhang, Ilona M. Vuist, Vivi Rottschäfer, Elizabeth C. M. de Lange
3citations -
Non-invasive characterization of pericyte dysfunction in mouse brain using functional ultrasound localization microscopy2025 Nature Biomedical Engineering article Neuroscience Barrier Structure and Function Studies Open access
Jérémy H. Thalgott, Nicolas Zucker, Thomas Deffieux, Marit S Koopman, Alexandre Dizeux, M. Cristina Avramut, +5 more
11citations -
Safety, Tolerability and Pharmacokinetic-Pharmacodynamic Relationship of NX210c Peptide in Healthy Elderly Volunteers: Randomized, Placebo-Controlled, Double-Blind, Multiple Ascending Dose Study
Annette Janus, Juliette Le Douce, Sébastien Marie, Giuseppe Pasculli, Pauline Bambury, Sighild Lemarchant, +2 more
4citations