-
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance2021 Nature Communications article Medicine PARP inhibition in cancer therapy Open access cited by 18 patents
Diana A. Zatreanu, Helen M.R. Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, +53 more
370citations -
Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial2020 Nature Communications article Medicine Dietary Effects on Health Open access cited by 5 patents
Stefanie de Groot, Rieneke T. Lugtenberg, Danielle Cohen, Marij J.P. Welters, Ilina Ehsan, Maaike P.G. Vreeswijk, +21 more
350citations -
Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury2021 Nature Communications article Medicine Ferroptosis and cancer prognosis Open access cited by 4 patents
Wulf Tonnus, Claudia Meyer, Christian Steinebach, Alexia Belavgeni, Anne von Mäßenhausen, Nadia Zamora Gonzalez, +26 more
269citations -
Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome2021 Nature Communications article Medicine Parkinson's Disease Mechanisms and Treatments Open access cited by 1 patent
Catherine S. Storm, Demis A. Kia, Mona Mohammad Almramhi, Sara Bandrés Ciga, Chris Finan, Alastair John Noyce, +94 more
209citations -
Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance2020 Nature Communications article Medicine Liver Disease Diagnosis and Treatment Open access cited by 3 patents
Kay H. M. Roumans, Lucas Lindeboom, Pandichelvam Veeraiah, Carlijn M. E. Remie, Esther Phielix, Bas Havekes, +11 more
146citations -
The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution2020 Nature Communications article Medicine Genetic factors in colorectal cancer Open access cited by 1 patent
Alexej Ballhausen, Moritz Jakob Przybilla, Michael Adrian Jendrusch, Saskia Haupt, Elisabeth Pfaffendorf, Florian Seidler, +24 more
138citations -
Plasmid-mediated metronidazole resistance in Clostridioides difficile2020 Nature Communications article Medicine Clostridium difficile and Clostridium perfringens research Open access
Ilse M. Boekhoud, Bastian Volker Helmut Hornung, Eloísa Sevilla, Céline Harmanus, Ingrid M. J. G. Bos-Sanders, Elisabeth M. Terveer, +4 more
137citations -
Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity2021 Nature Communications article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 12 patents
Cyrielle E. Fougeroux, Louise Goksøyr, Manja Idorn, Vladislav Soroka, Sebenzile K. Myeni, Robert Dagil, +41 more
132citations -
Large language models streamline automated machine learning for clinical studies2024 Nature Communications article Medicine Artificial Intelligence in Healthcare and Education Open access
Soroosh Tayebi Arasteh, Tianyu Han, Mahshad Lotfinia, Christiane Katharina Kuhl, Jakob Nikolas Kather, Daniel Truhn, +1 more
115citations -
Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment2023 Nature Communications article Medicine Cancer Immunotherapy and Biomarkers Open access cited by 2 patents
Markus Haake, Beatrice Haack, Tina Schäfer, Patrick N. Harter, Greta Mattavelli, Patrick Eiring, +47 more
108citations -
Microbiota-based markers predictive of development of Clostridioides difficile infection2021 Nature Communications article Medicine Clostridium difficile and Clostridium perfringens research Open access cited by 1 patent
Matilda Berkell, Mohamed Mysara, Basil Britto Xavier, Cornelis H. van Werkhoven, Pieter Monsieurs, Christine Lammens, +50 more
93citations -
CD229 CAR T cells eliminate multiple myeloma and tumor propagating cells without fratricide2020 Nature Communications article Medicine CAR-T cell therapy research Open access cited by 4 patents
Sabarinath Venniyil Radhakrishnan, Tim Luetkens, Sandra D. Scherer, Patricia M. Davis, Erica R. Vander Mause, Michael Olson, +8 more
79citations