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Papers matching “T cell receptor engineering” 67

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Combinatorial T cell engineering eliminates on-target off-tumor toxicity of CD229 CAR T cells while maintaining anti-tumor activity
2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine CAR-T cell therapy research

Erica R. Vander Mause, Kenneth A. Dietze, Sabarinath Venniyil Radhakrishnan, Thierry Iraguha, Patricia M. Davis, Jens Panse, +7 more

1

citations
Immunoglobulin constant domains as targets for T-cell receptor–based treatment of multiple myeloma
2026 Blood article Medicine CAR-T cell therapy research

Miranda H. Meeuwsen, Anne K. Wouters, Johannes C. Wellershoff, Tassilo L A Wachsmann, Dennis F.G. Remst, Renate S. Hagedoorn, +9 more

1

citations
HA-1H T-Cell Receptor Gene Transfer to Redirect Virus-Specific T Cells for Treatment of Hematological Malignancies After Allogeneic Stem Cell Transplantation: A Phase 1 Clinical Study
2020 Frontiers in Immunology article Medicine Hematopoietic Stem Cell Transplantation Open access

Peter van Balen, Inge Jedema, Marleen M. van Loenen, Renate de Boer, H.M. van Egmond, Renate S. Hagedoorn, +9 more

42

citations
Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance
2021 Frontiers in Immunology article Medicine CAR-T cell therapy research Open access cited by 6 patents

Yannick D. Müller, Leonardo M. R. Ferreira, Émilie Ronin, Patrick Ho, Vinh Q. Nguyen, Gaetano Faleo, +10 more

109

citations
Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance
2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine CAR-T cell therapy research Open access cited by 6 patents

Yannick D. Müller, Leonardo M. R. Ferreira, Émilie Ronin, Patrick Ho, Vinh Q. Nguyen, Gaetano Faleo, +10 more

11

citations
Targeting epigenetic regulation and post-translational modification with 5-Aza-2’ deoxycytidine and SUMO E1 inhibition augments T-cell receptor therapy
2024 Journal for ImmunoTherapy of Cancer article Medicine CAR-T cell therapy research Open access

Jessie S. Kroonen, Anne K. Wouters, Ilona J. de Graaf, Dennis F.G. Remst, Sumit Kumar, Tassilo L A Wachsmann, +6 more

9

citations
Abstract 4058: In vitro binding, efficacy and safety studies to support engineered T cell therapies
2023 Cancer Research conference-abstract Medicine CAR-T cell therapy research

Sophie Vermond, Benita Quist, Monique Hazenoot, Rene J. McLaughlin, David Cobeta Lopez, Namrata Jayanth, +5 more

0

citations
Abstract 3232: In vitro cell based cytotoxicity and T cell activation assays to assess safety and efficacy of engineered T cell therapies
2020 Cancer Research conference-abstract Medicine CAR-T cell therapy research

Sanne L. Holt, Sophie Vermond, Monique Hazenoot, Jeroen Paardekooper Overman, Jamil Aarbiou, Jeroen DeGroot

0

citations
Chimeric HLA antibody receptor T cell therapy for humoral transplant rejection
2024 Nephrology Dialysis Transplantation article Medicine Renal Transplantation Outcomes and Treatments Open access

Carolt Arana, Ainhoa García‐Busquets, M Nicoli, Sergi Betriu, Ilse Gille, Mirjam H.M. Heemskerk, +4 more

10

citations
CAR-mediated target recognition limits TCR-mediated target recognition of TCR- and CAR-dual-receptor-edited T cells
2025 Molecular Therapy article Medicine CAR-T cell therapy research Open access

Tassilo L A Wachsmann, Teuntje Poortvliet, Miranda H. Meeuwsen, Dennis F.G. Remst, Marijke F Toes, Anne K. Wouters, +3 more

9

citations
Abstract 1373: Primary or iPSC-derived cell-based cytotoxicity assays to assess potential safety risks of engineered T cell therapies in vitro
2021 Cancer Research conference-abstract Medicine CAR-T cell therapy research

Sanne L. Holt, Sophie Vermond, Monique Hazenoot, Rene J. McLaughlin, Marco Guadagnoli, Marijn Vlaming

0

citations
Comparing CAR and TCR engineered T cell performance as a function of tumor cell exposure
2022 OncoImmunology article Medicine CAR-T cell therapy research Open access cited by 2 patents

Tassilo L A Wachsmann, Anne K. Wouters, Dennis F.G. Remst, Renate S. Hagedoorn, Miranda H. Meeuwsen, Eline van Diest, +4 more

60

citations
Chimeric HLA antibody receptor T cells to target HLA ‐specific B cells in solid organ transplantation
2023 HLA article Medicine CAR-T cell therapy research Open access cited by 2 patents

Ilse Gille, Renate S. Hagedoorn, Ellen M. W. van der Meer‐Prins, Mirjam H.M. Heemskerk, Sebastiaan Heidt

15

citations
Abstract 5576: In vitro efficacy and safety studies to support engineered T cell therapies
2022 Cancer Research conference-abstract Medicine CAR-T cell therapy research

Sophie Vermond, Benita Quist, Sabrina de Munnik, Monique Hazenoot, Madalina Avramescu, Rene J. McLaughlin, +2 more

0

citations
Abstract 294: In vitro efficacy studies to support engineered T cell therapies
2021 Cancer Research conference-abstract Medicine CAR-T cell therapy research

Sanne L. Holt, Sophie Vermond, Monique Hazenoot, Rene J. McLaughlin, Marco Guadagnoli, Marijn Vlaming

0

citations
Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia
2022 Science Translational Medicine article Medicine CAR-T cell therapy research Open access cited by 2 patents

Giorgio Ottaviano, Christos Georgiadis, Soragia Athina Gkazi, Farhatullah Syed, Hong Zhan, Annie Etuk, +52 more

204

citations
T-cell receptors targeting distinct FLT3-D835Y neoantigens display differential reactivity toward acute myeloid leukemia
2026 Blood Immunology & Cellular Therapy article Medicine Acute Myeloid Leukemia Research Open access

Nadine Struckman, M. Willy Honders, Georgia Koutsoumpli, Rob C. M. de Jong, Dyantha I. van der Lee, Michel G.D. Kester, +11 more

0

citations
Identification of Functional HLA-A*01:01–Restricted Epstein-Barr Latent Membrane Protein 2–Specific T-Cell Receptors
2020 The Journal of Infectious Diseases article Medicine CAR-T cell therapy research Open access

Wesley Huisman, Ilse Gille, Lieve E. van der Maarel, Lois Hageman, Laura T. Morton, Rob C. M. de Jong, +4 more

11

citations
Abstract 4802: CAR-T cell therapy workflow for discovery and development
2025 Cancer Research conference-abstract Medicine CAR-T cell therapy research

David Cobeta Lopez, Benita Quist, Sara Compte-Sancerni, Sophie Vermond, Namrata Jayanth, Monika Hiller, +10 more

0

citations
148 Primary or iPSC-derived cell-based cytotoxicity assays to assess potential safety risks of engineered T cell therapies in vitro
2021 Regular and Young Investigator Award Abstracts conference-abstract Medicine CAR-T cell therapy research Open access

Sophie Vermond, Monique Hazenoot, Rene J. McLaughlin, Sabrina de Munnik, Marco Guadagnoli, Gemma Moiset, +2 more

0

citations
PB1703: MODELING T-CELL DEVELOPMENT AND T-ALL INITIATION
2023 HemaSphere article Medicine Acute Lymphoblastic Leukemia research Open access

Advaita M Dick, Erika Tsingos, Narges Aghaallaei, Julia Skokowa, Baubak Bajoghli

0

citations
CD103 and CD39 coexpression identifies neoantigen-specific cytotoxic T cells in colorectal cancers with low mutation burden
2023 Journal for ImmunoTherapy of Cancer article Medicine Cancer Immunotherapy and Biomarkers Open access

Jitske van den Bulk, Manon van der Ploeg, Marieke E. Ijsselsteijn, Dina Ruano, Ruud van der Breggen, Rebekka Duhen, +6 more

29

citations
Automated manufacture of ΔNPM1 TCR-engineered T cells for AML therapy
2024 Molecular Therapy — Methods & Clinical Development article Medicine CAR-T cell therapy research Open access

Isabella Elias Yonezawa Ogusuku, Vera Herbel, Simon Lennartz, Caroline Brandes, Eva M. Argiro, C. Fabian, +12 more

8

citations
Advances in preclinical TCR characterization: leveraging cell avidity to identify functional TCRs
2024 Biological Chemistry article Medicine CAR-T cell therapy research

Andreas Carr, Laura Marlene Mateyka, Sebastian J. C. Scheu, Ana Bici, Joris Paijmans, Rogier M. Reijmers, +6 more

9

citations
Quantitative Clinical Pharmacology of CAR T‐Cell Therapy
2022 Clinical Pharmacology & Therapeutics article Medicine CAR-T cell therapy research Open access

Sarah A. Holstein, Karthik Venkatakrishnan, Piet H. van der Graaf

5

citations