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Translational Application of the Five-Star Matrix for the Structure-Guided Optimization of a Bicyclopiperazine DEL Hit into Bcpz 1.5: A Potent Monoacylglycerol Lipase Inhibitor with Functional Inhibition in Human Brain Homogenate and Efficacy in Neuroinflammatory Models
Benjamin Brennecke, Louise Plais, Benoit Hornsperger, Martin Binder, Christian Bartelmus, Markus Bürkler, +32 more
0citations -
Prediction of the Extent of Blood–Brain Barrier Transport Using Machine Learning and Integration into the LeiCNS-PK3.0 Model2025 Pharmaceutical Research article Computer Science Computational Drug Discovery Methods Open access
Berfin Gülave, Helle W. van den Maagdenberg, Luke van Boven, Gerard J. P. van Westen, Elizabeth C. M. de Lange, J. G. Coen van Hasselt
7citations -
The coming decade of digital brain research - A vision for neuroscience at the intersection of technology and computing2022 Zenodo (CERN European Organization for Nuclear Research) article Computer Science Cognitive Computing and Networks Open access
Katrin Amunts, Markus Axer, Lise Bitsch, Jan Gunnar Bjaalie, Andrea Brovelli, Svenja Caspers, +40 more
14citations -
The coming decade of digital brain research - A vision for neuroscience at the intersection of technology and computing2023 Zenodo (CERN European Organization for Nuclear Research) article Computer Science Cognitive Computing and Networks Open access
Katrin Amunts, Markus Axer, Lise Bitsch, Jan Gunnar Bjaalie, Brauner Philipp, Andrea Brovelli, +91 more
3citations -
The coming decade of digital brain research - A vision for neuroscience at the intersection of technology and computing2022 Zenodo (CERN European Organization for Nuclear Research) article Computer Science Cognitive Computing and Networks Open access
Katrin Amunts, Markus Axer, Lise Bitsch, Jan Gunnar Bjaalie, Andrea Brovelli, Svenja Caspers, +55 more
1citations -
The coming decade of digital brain research - A vision for neuroscience at the intersection of technology and computing2022 Zenodo (CERN European Organization for Nuclear Research) article Computer Science Cognitive Computing and Networks Open access
Katrin Amunts, Markus Axer, Lise Bitsch, Jan Gunnar Bjaalie, Andrea Brovelli, Svenja Caspers, +74 more
1citations -
Fully Automatic Adaptive Meshing Based Segmentation of the Ventricular System for Augmented Reality Visualization and Navigation2021 World Neurosurgery article Computer Science Medical Image Segmentation Techniques Open access cited by 1 patent
Jesse A. M. van Doormaal, Tim Fick, Meedie Ali, M. Kollen, Vince van der Kuijp, Tristan P. C. van Doormaal
18citations -
Multi-Cohort Federated Learning Shows Synergy in Mortality Prediction for MRI-Based and Metabolomics-Based Age Scores2025 Journal of Healthcare Informatics Research article Computer Science Machine Learning in Healthcare Open access
Pedro Mateus, Swier J.F. Garst, Jing Yu, Davy Cats, Mahlet Birhanu, Marian Beekman, +15 more
2citations -
Automated Deep Learning–based Segmentation of the Dentate Nucleus Using Quantitative Susceptibility Mapping MRI2025 Radiology Artificial Intelligence article Computer Science Medical Image Segmentation Techniques Open access
Diogo H. Shiraishi, Susmita Saha, Isaac Mawusi Adanyeguh, Sirio Cocozza, Louise A. Corben, Andreas Deistung, +34 more
4citations